JP2022515838A - アラキドン酸１５－リポキシゲナーゼ（ａｌｏｘ１５）阻害剤による呼吸器障害の治療 - Google Patents

アラキドン酸１５－リポキシゲナーゼ（ａｌｏｘ１５）阻害剤による呼吸器障害の治療 Download PDF

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JP2022515838A
JP2022515838A JP2021537818A JP2021537818A JP2022515838A JP 2022515838 A JP2022515838 A JP 2022515838A JP 2021537818 A JP2021537818 A JP 2021537818A JP 2021537818 A JP2021537818 A JP 2021537818A JP 2022515838 A JP2022515838 A JP 2022515838A
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alox15
nucleic acid
seq
acid molecule
light
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JPWO2020139830A5 (https=
JP2022515838A5 (https=
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ホロウィッツ、ジュリー
バラス、アリス
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Regeneron Pharmaceuticals Inc
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    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
    • A—HUMAN NECESSITIES
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    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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    • C12Y113/11033—Arachidonate 15-lipoxygenase (1.13.11.33)
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JP2021537818A 2018-12-28 2019-12-23 アラキドン酸１５－リポキシゲナーゼ（ａｌｏｘ１５）阻害剤による呼吸器障害の治療 Pending JP2022515838A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862785899P 2018-12-28 2018-12-28
US62/785,899 2018-12-28
PCT/US2019/068328 WO2020139830A2 (en) 2018-12-28 2019-12-23 Treatment of respiratory disorders with arachidonate15-lipoxygenase (alox15) inhibitors

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JP2022515838A true JP2022515838A (ja) 2022-02-22
JPWO2020139830A5 JPWO2020139830A5 (https=) 2022-12-13
JP2022515838A5 JP2022515838A5 (https=) 2022-12-13

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JP2021537818A Pending JP2022515838A (ja) 2018-12-28 2019-12-23 アラキドン酸１５－リポキシゲナーゼ（ａｌｏｘ１５）阻害剤による呼吸器障害の治療

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US (2) US12472241B2 (https=)
EP (1) EP3902567A2 (https=)
JP (1) JP2022515838A (https=)
KR (1) KR20210110623A (https=)
CN (1) CN113423435A (https=)
AU (1) AU2019417718B2 (https=)
CA (1) CA3124670A1 (https=)
IL (1) IL284046A (https=)
MX (1) MX2021007938A (https=)
NZ (1) NZ777336A (https=)
SG (1) SG11202106517WA (https=)
WO (1) WO2020139830A2 (https=)

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EP3911632A1 (en) 2019-01-15 2021-11-24 Empirico Inc. Prodrugs of alox-15 inhibitors and methods of using the same

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SG11202106517WA (en) 2021-07-29
WO2020139830A3 (en) 2020-08-06
EP3902567A2 (en) 2021-11-03
US20260097102A1 (en) 2026-04-09
CN113423435A (zh) 2021-09-21
WO2020139830A2 (en) 2020-07-02
MX2021007938A (es) 2022-01-24
IL284046A (en) 2021-08-31
AU2019417718B2 (en) 2026-03-26
NZ777336A (en) 2026-02-27
KR20210110623A (ko) 2021-09-08
US12472241B2 (en) 2025-11-18
AU2019417718A1 (en) 2021-07-08
US20200254070A1 (en) 2020-08-13
CA3124670A1 (en) 2020-07-02

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