JP2022514253A5 - - Google Patents
Info
- Publication number
- JP2022514253A5 JP2022514253A5 JP2021534200A JP2021534200A JP2022514253A5 JP 2022514253 A5 JP2022514253 A5 JP 2022514253A5 JP 2021534200 A JP2021534200 A JP 2021534200A JP 2021534200 A JP2021534200 A JP 2021534200A JP 2022514253 A5 JP2022514253 A5 JP 2022514253A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- pyridine
- sulfonyl
- methylphenoxy
- cyclopropane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862781139P | 2018-12-18 | 2018-12-18 | |
| US62/781,139 | 2018-12-18 | ||
| PCT/IB2019/060801 WO2020128768A1 (en) | 2018-12-18 | 2019-12-13 | N-(pyridin-2-ylsulfonyl)cyclopropanecarboxamide derivatives and their use in the treatment of a cftr mediated disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022514253A JP2022514253A (ja) | 2022-02-10 |
| JP2022514253A5 true JP2022514253A5 (enExample) | 2022-12-19 |
Family
ID=69143626
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021534200A Pending JP2022514253A (ja) | 2018-12-18 | 2019-12-13 | Ｎ－（ピリジン－２－イルスルホニル）シクロプロパンカルボキサミド誘導体及びｃｆｔｒ媒介疾患の処置におけるその使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20220033407A1 (enExample) |
| EP (1) | EP3897832B1 (enExample) |
| JP (1) | JP2022514253A (enExample) |
| CN (1) | CN113226464A (enExample) |
| WO (1) | WO2020128768A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UY38806A (es) * | 2019-08-01 | 2021-02-26 | Novartis Ag | Compuestos inhibidores tricíclicos de kars dependientes de akr1c3, composiciones y sus usos |
| WO2022194399A1 (en) | 2020-07-13 | 2022-09-22 | Idorsia Pharmaceuticals Ltd | Macrocycles as cftr modulators |
| CN119907667A (zh) | 2022-09-15 | 2025-04-29 | 爱杜西亚药品有限公司 | 大环cftr调节剂与cftr校正剂和/或cftr增效剂的组合 |
| CA3267791A1 (en) | 2022-09-15 | 2024-03-21 | Idorsia Pharmaceuticals Ltd | CRYSTALLINE FORM OF (3S,7S,10R,13R)-13-BENZYL-20-FLUORO-7-ISOBUTYL-N-(2-(3-METHOXY-1,2,4-OXADIAZOL-5-YL)ETHYL)-6,9-DIMETHYL-1,5,8,11-TETRAOXO-10-(2,2,2-TRIFLUOROETHYL)-1,2,3,4,5,6,7,8,9,10,11,12,13,14-TETRADECAHYDRO-[1]OXA[4,7,10,14]TETRAAZACYCLOHEPTADECINO [16,17-F]QUINOLINE-3-CARBOXAMIDE |
| WO2024056798A1 (en) | 2022-09-15 | 2024-03-21 | Idorsia Pharmaceuticals Ltd | Macrocyclic cftr modulators |
| CN115616024B (zh) * | 2022-12-19 | 2023-03-21 | 苏州大学 | 一种液晶聚酯的组分分析方法 |
| WO2025087274A1 (zh) | 2023-10-27 | 2025-05-01 | 浙江海正药业股份有限公司 | 氮杂双环类衍生物及其制备方法和用途 |
| WO2025186214A1 (en) | 2024-03-05 | 2025-09-12 | Idorsia Pharmaceuticals Ltd | Macrocyclic cftr modulators |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004078163A2 (en) | 2003-02-28 | 2004-09-16 | Transform Pharmaceuticals, Inc. | Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen |
| US7776875B2 (en) * | 2007-12-19 | 2010-08-17 | Hoffman-La Roche Inc. | Spiroindolinone derivatives |
| TW202140422A (zh) * | 2014-10-06 | 2021-11-01 | 美商維泰克斯製藥公司 | 囊腫纖維化症跨膜傳導調節蛋白之調節劑 |
| ES2946970T3 (es) * | 2016-03-31 | 2023-07-28 | Vertex Pharma | Regulador de conductancia transmembrana de moduladores de fibrosis quística |
| TW201811766A (zh) * | 2016-08-29 | 2018-04-01 | 瑞士商諾華公司 | N-(吡啶-2-基)吡啶-磺醯胺衍生物及其用於疾病治療之用途 |
| US10988454B2 (en) * | 2017-09-14 | 2021-04-27 | Abbvie Overseas S.À.R.L. | Modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use |
-
2019
- 2019-12-13 CN CN201980083034.2A patent/CN113226464A/zh active Pending
- 2019-12-13 JP JP2021534200A patent/JP2022514253A/ja active Pending
- 2019-12-13 WO PCT/IB2019/060801 patent/WO2020128768A1/en not_active Ceased
- 2019-12-13 US US17/414,672 patent/US20220033407A1/en not_active Abandoned
- 2019-12-13 EP EP19832736.3A patent/EP3897832B1/en active Active
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