JP2022512941A5 - - Google Patents

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Publication number
JP2022512941A5
JP2022512941A5 JP2021524356A JP2021524356A JP2022512941A5 JP 2022512941 A5 JP2022512941 A5 JP 2022512941A5 JP 2021524356 A JP2021524356 A JP 2021524356A JP 2021524356 A JP2021524356 A JP 2021524356A JP 2022512941 A5 JP2022512941 A5 JP 2022512941A5
Authority
JP
Japan
Prior art keywords
substituted
unsubstituted
cationic amphiphilic
amphiphilic polymer
nhc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021524356A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022512941A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/060807 external-priority patent/WO2020097614A2/en
Publication of JP2022512941A publication Critical patent/JP2022512941A/ja
Publication of JP2022512941A5 publication Critical patent/JP2022512941A5/ja
Pending legal-status Critical Current

Links

JP2021524356A 2018-11-09 2019-11-11 核酸送達のためのハイブリッド犠牲細胞透過性複合体 Pending JP2022512941A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862758487P 2018-11-09 2018-11-09
US62/758,487 2018-11-09
PCT/US2019/060807 WO2020097614A2 (en) 2018-11-09 2019-11-11 Hybrid immolative cell-penetrating complexes for nucleic acid delivery

Publications (2)

Publication Number Publication Date
JP2022512941A JP2022512941A (ja) 2022-02-07
JP2022512941A5 true JP2022512941A5 (enExample) 2022-11-17

Family

ID=70612292

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021524356A Pending JP2022512941A (ja) 2018-11-09 2019-11-11 核酸送達のためのハイブリッド犠牲細胞透過性複合体

Country Status (9)

Country Link
US (1) US12215341B2 (enExample)
EP (1) EP3877002A4 (enExample)
JP (1) JP2022512941A (enExample)
KR (1) KR20210125979A (enExample)
CN (1) CN113573740A (enExample)
AU (1) AU2019377137B2 (enExample)
CA (1) CA3119288A1 (enExample)
IL (1) IL283037A (enExample)
WO (1) WO2020097614A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4185331A4 (en) * 2020-07-24 2025-02-26 The Board of Trustees of the Leland Stanford Junior University THREE-COMPONENT VACCINE FOR COVID-19
US20250177559A1 (en) 2022-03-09 2025-06-05 The Board Of Trustees Of The Leland Stanford Junior University Branched lipid charge-altering releasable transporters for nucleic acid delivery
US20260103709A1 (en) 2022-09-29 2026-04-16 The Board Of Trustees Of The Leland Stanford Junior University C-myc-targeting charge-altering releasable transporters as anti-tumor agents for breast cancer therapy
EP4615508A1 (en) 2022-11-08 2025-09-17 The Board Of Trustees Of The Leland Stanford Junior University Charge-altering nucleic acid transporters with beta-amido carbonate backbones
WO2025034780A1 (en) * 2023-08-08 2025-02-13 The Board Of Trustees Of The Leland Stanford Junior University Statistical charge-altering releasable transporters for nucleic acid delivery
WO2025034782A1 (en) * 2023-08-08 2025-02-13 The Board Of Trustees Of The Leland Stanford Junior University Charge-altering releasable transporters from amino alcohol initiators
US20250302763A1 (en) * 2024-02-22 2025-10-02 Capstan Therapeutics, Inc. Immune engineering amplification
WO2026026972A1 (zh) * 2024-08-01 2026-02-05 苏州百递博远生物科技有限公司 核酸递送载体及其制备与应用
WO2026026974A1 (zh) * 2024-08-01 2026-02-05 苏州百递博远生物科技有限公司 功能性聚碳酸酯及其制备方法与应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5235033A (en) 1985-03-15 1993-08-10 Anti-Gene Development Group Alpha-morpholino ribonucleoside derivatives and polymers thereof
JP2004535388A (ja) 2001-04-30 2004-11-25 ターゲティッド ジェネティクス コーポレイション 脂質含有薬物送達複合体およびそれらの生成方法
WO2003106636A2 (en) * 2002-06-14 2003-12-24 Mirus Corporation Novel methods for the delivery of polynucleotides to cells
US9902957B2 (en) 2011-09-06 2018-02-27 The Board Of Trustees Of The Leland Stanford Junior University Amphipathic co-oligomers for the delivery of siRNA
US20150329640A1 (en) * 2012-12-20 2015-11-19 Bluebird Bio, Inc. Chimeric antigen receptors and immune cells targeting b cell malignancies
AU2016243583B2 (en) * 2015-03-27 2022-03-10 President And Fellows Of Harvard College Modified T cells and methods of making and using the same
US10654875B2 (en) 2015-11-12 2020-05-19 The Board Of Trustees Of The Leland Stanford Junior University Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery
CN115252807A (zh) * 2016-07-27 2022-11-01 利兰斯坦福初级大学董事会 用于核酸递送的解体型细胞穿透性复合物

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