CN113573740A - 用于核酸递送的混合分解细胞穿透复合物 - Google Patents

用于核酸递送的混合分解细胞穿透复合物 Download PDF

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Publication number
CN113573740A
CN113573740A CN201980085871.9A CN201980085871A CN113573740A CN 113573740 A CN113573740 A CN 113573740A CN 201980085871 A CN201980085871 A CN 201980085871A CN 113573740 A CN113573740 A CN 113573740A
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T·R·布莱克
R·M·韦茂思
P·温德
R·利维
O·A·W·哈贝特
M·弗兰克
A·萨莱茨
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Leland Stanford Junior University
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CN201980085871.9A 2018-11-09 2019-11-11 用于核酸递送的混合分解细胞穿透复合物 Pending CN113573740A (zh)

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US201862758487P 2018-11-09 2018-11-09
US62/758,487 2018-11-09
PCT/US2019/060807 WO2020097614A2 (en) 2018-11-09 2019-11-11 Hybrid immolative cell-penetrating complexes for nucleic acid delivery

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US (1) US12215341B2 (enExample)
EP (1) EP3877002A4 (enExample)
JP (1) JP2022512941A (enExample)
KR (1) KR20210125979A (enExample)
CN (1) CN113573740A (enExample)
AU (1) AU2019377137B2 (enExample)
CA (1) CA3119288A1 (enExample)
IL (1) IL283037A (enExample)
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Cited By (2)

* Cited by examiner, † Cited by third party
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WO2026026974A1 (zh) * 2024-08-01 2026-02-05 苏州百递博远生物科技有限公司 功能性聚碳酸酯及其制备方法与应用
WO2026026972A1 (zh) * 2024-08-01 2026-02-05 苏州百递博远生物科技有限公司 核酸递送载体及其制备与应用

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EP4185331A4 (en) * 2020-07-24 2025-02-26 The Board of Trustees of the Leland Stanford Junior University THREE-COMPONENT VACCINE FOR COVID-19
US20250177559A1 (en) 2022-03-09 2025-06-05 The Board Of Trustees Of The Leland Stanford Junior University Branched lipid charge-altering releasable transporters for nucleic acid delivery
US20260103709A1 (en) 2022-09-29 2026-04-16 The Board Of Trustees Of The Leland Stanford Junior University C-myc-targeting charge-altering releasable transporters as anti-tumor agents for breast cancer therapy
EP4615508A1 (en) 2022-11-08 2025-09-17 The Board Of Trustees Of The Leland Stanford Junior University Charge-altering nucleic acid transporters with beta-amido carbonate backbones
WO2025034780A1 (en) * 2023-08-08 2025-02-13 The Board Of Trustees Of The Leland Stanford Junior University Statistical charge-altering releasable transporters for nucleic acid delivery
WO2025034782A1 (en) * 2023-08-08 2025-02-13 The Board Of Trustees Of The Leland Stanford Junior University Charge-altering releasable transporters from amino alcohol initiators
US20250302763A1 (en) * 2024-02-22 2025-10-02 Capstan Therapeutics, Inc. Immune engineering amplification

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WO2002088318A2 (en) * 2001-04-30 2002-11-07 Targeted Genetics Corporation Lipid-comprising drug delivery complexes and methods for their production
WO2003106636A2 (en) * 2002-06-14 2003-12-24 Mirus Corporation Novel methods for the delivery of polynucleotides to cells
US20180028688A1 (en) * 2016-07-27 2018-02-01 The Board Of Trustees Of The Leland Stanford Junior University Immolative cell-penetrating complexes for nucleic acid delivery

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US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5235033A (en) 1985-03-15 1993-08-10 Anti-Gene Development Group Alpha-morpholino ribonucleoside derivatives and polymers thereof
US9902957B2 (en) 2011-09-06 2018-02-27 The Board Of Trustees Of The Leland Stanford Junior University Amphipathic co-oligomers for the delivery of siRNA
US20150329640A1 (en) * 2012-12-20 2015-11-19 Bluebird Bio, Inc. Chimeric antigen receptors and immune cells targeting b cell malignancies
AU2016243583B2 (en) * 2015-03-27 2022-03-10 President And Fellows Of Harvard College Modified T cells and methods of making and using the same
US10654875B2 (en) 2015-11-12 2020-05-19 The Board Of Trustees Of The Leland Stanford Junior University Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery

Patent Citations (3)

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Publication number Priority date Publication date Assignee Title
WO2002088318A2 (en) * 2001-04-30 2002-11-07 Targeted Genetics Corporation Lipid-comprising drug delivery complexes and methods for their production
WO2003106636A2 (en) * 2002-06-14 2003-12-24 Mirus Corporation Novel methods for the delivery of polynucleotides to cells
US20180028688A1 (en) * 2016-07-27 2018-02-01 The Board Of Trustees Of The Leland Stanford Junior University Immolative cell-penetrating complexes for nucleic acid delivery

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026026974A1 (zh) * 2024-08-01 2026-02-05 苏州百递博远生物科技有限公司 功能性聚碳酸酯及其制备方法与应用
WO2026026972A1 (zh) * 2024-08-01 2026-02-05 苏州百递博远生物科技有限公司 核酸递送载体及其制备与应用

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US20220088163A1 (en) 2022-03-24
EP3877002A4 (en) 2022-11-02
AU2019377137A1 (en) 2021-05-27
US12215341B2 (en) 2025-02-04
EP3877002A2 (en) 2021-09-15
CA3119288A1 (en) 2020-05-14
IL283037A (en) 2021-06-30
KR20210125979A (ko) 2021-10-19
JP2022512941A (ja) 2022-02-07
WO2020097614A2 (en) 2020-05-14
AU2019377137B2 (en) 2025-12-11
WO2020097614A3 (en) 2020-06-11

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Application publication date: 20211029