JP2022508609A5 - - Google Patents
Info
- Publication number
- JP2022508609A5 JP2022508609A5 JP2021543970A JP2021543970A JP2022508609A5 JP 2022508609 A5 JP2022508609 A5 JP 2022508609A5 JP 2021543970 A JP2021543970 A JP 2021543970A JP 2021543970 A JP2021543970 A JP 2021543970A JP 2022508609 A5 JP2022508609 A5 JP 2022508609A5
- Authority
- JP
- Japan
- Prior art keywords
- hypertonic solution
- composition
- solution according
- interstitium
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024064529A JP2024099600A (ja) | 2018-10-04 | 2024-04-12 | 血漿浸透圧を操作することによるグリンパティック送達の改善 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862741295P | 2018-10-04 | 2018-10-04 | |
| US62/741,295 | 2018-10-04 | ||
| PCT/US2019/053808 WO2020072357A1 (en) | 2018-10-04 | 2019-09-30 | Improvement of glymphatic delivery by manipulating plasma osmolarity |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024064529A Division JP2024099600A (ja) | 2018-10-04 | 2024-04-12 | 血漿浸透圧を操作することによるグリンパティック送達の改善 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022508609A JP2022508609A (ja) | 2022-01-19 |
| JP2022508609A5 true JP2022508609A5 (enExample) | 2022-06-08 |
| JP7611149B2 JP7611149B2 (ja) | 2025-01-09 |
Family
ID=68502006
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021543970A Active JP7611149B2 (ja) | 2018-10-04 | 2019-09-30 | 血漿浸透圧を操作することによるグリンパティック送達の改善 |
| JP2024064529A Withdrawn JP2024099600A (ja) | 2018-10-04 | 2024-04-12 | 血漿浸透圧を操作することによるグリンパティック送達の改善 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024064529A Withdrawn JP2024099600A (ja) | 2018-10-04 | 2024-04-12 | 血漿浸透圧を操作することによるグリンパティック送達の改善 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US12311035B2 (enExample) |
| EP (1) | EP3860564A1 (enExample) |
| JP (2) | JP7611149B2 (enExample) |
| KR (1) | KR20210100086A (enExample) |
| CN (1) | CN113226283A (enExample) |
| AU (1) | AU2019354965B2 (enExample) |
| CA (1) | CA3115071A1 (enExample) |
| WO (1) | WO2020072357A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4175698A4 (en) * | 2020-08-03 | 2024-07-31 | Transluminal Systems, LLC | DEVICES AND METHODS FOR ARTERIAL OSMOTIC EMBOLIZATION OF PATHOLOGICAL TISSUES |
| US20250235554A1 (en) * | 2021-10-25 | 2025-07-24 | Novartis Ag | Methods for improving adeno-associated virus (aav) delivery |
| AU2024220563A1 (en) | 2023-02-16 | 2025-08-14 | University Of Rochester | Improving glymphatic-lymphatic efflux |
| US12483569B2 (en) | 2024-03-28 | 2025-11-25 | Bank Of America Corporation | System and method for identifying unauthorized data traffic in a computing network |
| WO2025250454A1 (en) * | 2024-05-28 | 2025-12-04 | University Of Rochester | Adeno-associated viruses evolved to specifically target human glial progenitor cells in vivo |
Family Cites Families (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5869248A (en) | 1994-03-07 | 1999-02-09 | Yale University | Targeted cleavage of RNA using ribonuclease P targeting and cleavage sequences |
| US5599706A (en) | 1994-09-23 | 1997-02-04 | Stinchcomb; Dan T. | Ribozymes targeted to apo(a) mRNA |
| DE69636937T3 (de) | 1995-12-15 | 2011-01-05 | Virxsys Corp. | Durch trans-spaltung erhaltene therapeutische molekule |
| US6083702A (en) | 1995-12-15 | 2000-07-04 | Intronn Holdings Llc | Methods and compositions for use in spliceosome mediated RNA trans-splicing |
| IL151378A0 (en) | 2000-02-24 | 2003-04-10 | Univ Washington | Humanized antibodies that sequester amyloid beta peptide |
| US7943129B2 (en) | 2000-05-26 | 2011-05-17 | National Research Council Of Canada | Single-domain brain-targeting antibody fragments derived from llama antibodies |
| EP2082749A3 (en) | 2000-07-07 | 2010-06-30 | Bioarctic Neuroscience AB | Prevention and treatment of Alzheimer's disease |
| TWI255272B (en) | 2000-12-06 | 2006-05-21 | Guriq Basi | Humanized antibodies that recognize beta amyloid peptide |
| JP2005500389A (ja) | 2001-08-17 | 2005-01-06 | イーライ・リリー・アンド・カンパニー | Aβに関連する病態および疾患を治療するための、可溶性Aβに高い親和性を有する抗体の使用 |
| CA2451998A1 (en) | 2001-08-17 | 2003-02-27 | Eli Lilly And Company | Anti-a.beta. antibodies |
| MY139983A (en) | 2002-03-12 | 2009-11-30 | Janssen Alzheimer Immunotherap | Humanized antibodies that recognize beta amyloid peptide |
| WO2004029629A1 (en) | 2002-09-27 | 2004-04-08 | Janssen Pharmaceutica N.V. | N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses |
| EP1633786A4 (en) | 2002-10-09 | 2007-07-25 | Rinat Neuroscience Corp | METHOD FOR TREATING ALZHEIMER DISEASE WITH ANTIBODIES TO AMYLOID BETA PEPTIDE AND COMPOSITIONS THEREOF |
| US20050142141A1 (en) | 2002-11-27 | 2005-06-30 | Pardridge William M. | Delivery of enzymes to the brain |
| EP1613657A2 (en) | 2003-03-28 | 2006-01-11 | Centocor, Inc. | Anti-amyloid antibodies, compositions, methods and uses |
| PE20050627A1 (es) | 2003-05-30 | 2005-08-10 | Wyeth Corp | Anticuerpos humanizados que reconocen el peptido beta amiloideo |
| US8801541B2 (en) | 2007-09-27 | 2014-08-12 | Taylor Made Golf Company, Inc. | Golf club |
| WO2006014638A2 (en) * | 2004-07-19 | 2006-02-09 | The General Hospital Corporation | ANTIBODIES TO CROSS-LINKED AMYLOID β OLIGOMERS |
| GEP20115195B (en) | 2004-07-30 | 2011-04-11 | Rinat Neuroscience Corp | Antibodies directed against amyloid-beta peptide and use thereof |
| EP1799260A4 (en) | 2004-09-29 | 2011-09-28 | Centocor Inc | ANTI-AMYLOID ANTIBODIES, COMPOSITIONS, TECHNIQUES AND USES |
| PE20061329A1 (es) | 2004-12-15 | 2006-12-08 | Neuralab Ltd | Anticuerpos ab humanizados para mejorar la cognicion |
| ES2396555T3 (es) | 2004-12-15 | 2013-02-22 | Janssen Alzheimer Immunotherapy | Anticuerpos que reconocen péptido beta amiloide |
| US20060257396A1 (en) | 2004-12-15 | 2006-11-16 | Jacobsen Jack S | Abeta antibodies for use in improving cognition |
| ES2259270B1 (es) | 2005-03-09 | 2007-11-01 | Consejo Superior De Investigaciones Cientificas | Metodo de diagnostico in vitro de la enfermedad de alzheimer mediante un anticuerpo monoclonal. |
| WO2009027105A2 (en) | 2007-08-31 | 2009-03-05 | Neurimmune Therapeutics Ag | Method of providing patient specific immune response in amyloidoses and protein aggregation disorders |
| BR112012000908A2 (pt) | 2009-07-14 | 2019-09-24 | Mayo Found Medical Education & Res | liberação de agentes ativos através da barreira hematoencefálica mediada por peptídeo em associação não covalente |
| HUE039033T2 (hu) | 2012-01-10 | 2018-12-28 | Biogen Ma Inc | Terápiás molekulák transzportjának fokozása a vér-agy gáton keresztül |
| JP6382232B2 (ja) * | 2013-02-21 | 2018-08-29 | ユニバ−シティ オブ ロチェスタ− | 脳全体の傍血管経路を老廃物のクリアランス機能について評価するための方法、およびそれに基づいて神経変性障害を治療するための方法 |
| JP6779876B2 (ja) | 2014-11-19 | 2020-11-04 | ジェネンテック, インコーポレイテッド | 抗トランスフェリン受容体抗体及びその使用方法 |
| AU2016206624B2 (en) | 2015-01-14 | 2020-08-06 | The University Of North Carolina At Chapel Hill | Methods and compositions for targeted gene transfer |
| JP6824535B2 (ja) | 2015-09-11 | 2021-02-03 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 脳間質内のナノ粒子分布を改善するための組成物および方法 |
| US10123969B2 (en) * | 2015-10-15 | 2018-11-13 | Wisconsin Alumni Research Foundation | Osmotic enhancement of drug/therapeutic delivery to the brain following infusion or injection into the cerebrospinal fluid |
| AU2017207818B2 (en) * | 2016-01-15 | 2024-03-28 | Regents Of The University Of Minnesota | Methods and compositions for the treatment of neurologic disease |
| WO2017210343A1 (en) * | 2016-06-01 | 2017-12-07 | The University Of Virginia Patent Foundation | Methods and compositions for modulating lymphatic vessels in the central nervous system |
| US20190282792A1 (en) * | 2016-07-20 | 2019-09-19 | P&X Medical Nv | Compounds for use in methods for treating glaucoma and retinal diseases |
| US10457717B2 (en) | 2017-02-17 | 2019-10-29 | Denali Therapeutics Inc. | Engineered polypeptides |
-
2019
- 2019-09-30 WO PCT/US2019/053808 patent/WO2020072357A1/en not_active Ceased
- 2019-09-30 CA CA3115071A patent/CA3115071A1/en active Pending
- 2019-09-30 JP JP2021543970A patent/JP7611149B2/ja active Active
- 2019-09-30 CN CN201980075683.8A patent/CN113226283A/zh active Pending
- 2019-09-30 AU AU2019354965A patent/AU2019354965B2/en active Active
- 2019-09-30 EP EP19801124.9A patent/EP3860564A1/en active Pending
- 2019-09-30 US US17/280,606 patent/US12311035B2/en active Active
- 2019-09-30 KR KR1020217013589A patent/KR20210100086A/ko active Pending
-
2024
- 2024-04-12 JP JP2024064529A patent/JP2024099600A/ja not_active Withdrawn
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