JP2015520188A5 - - Google Patents
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- Publication number
- JP2015520188A5 JP2015520188A5 JP2015516010A JP2015516010A JP2015520188A5 JP 2015520188 A5 JP2015520188 A5 JP 2015520188A5 JP 2015516010 A JP2015516010 A JP 2015516010A JP 2015516010 A JP2015516010 A JP 2015516010A JP 2015520188 A5 JP2015520188 A5 JP 2015520188A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- hgh
- bolus dose
- xten
- fusion protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261689390P | 2012-06-05 | 2012-06-05 | |
| US61/689,390 | 2012-06-05 | ||
| US201261663475P | 2012-06-22 | 2012-06-22 | |
| US61/663,475 | 2012-06-22 | ||
| US201361763753P | 2013-02-12 | 2013-02-12 | |
| US61/763,753 | 2013-02-12 | ||
| PCT/US2013/031673 WO2013184216A1 (en) | 2012-06-05 | 2013-03-14 | Hgh-xten fusion protein and its use in the treatment of growth hormone deficiency |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017043512A Division JP2017125051A (ja) | 2012-06-05 | 2017-03-08 | Ｈｇｈ−ｘｔｅｎ融合タンパク質および成長ホルモン欠乏症の処置におけるその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015520188A JP2015520188A (ja) | 2015-07-16 |
| JP2015520188A5 true JP2015520188A5 (enExample) | 2016-05-12 |
Family
ID=47998551
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015516010A Pending JP2015520188A (ja) | 2012-06-05 | 2013-03-14 | Ｈｇｈ−ｘｔｅｎ融合タンパク質および成長ホルモン欠乏症の処置におけるその使用 |
| JP2017043512A Pending JP2017125051A (ja) | 2012-06-05 | 2017-03-08 | Ｈｇｈ−ｘｔｅｎ融合タンパク質および成長ホルモン欠乏症の処置におけるその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017043512A Pending JP2017125051A (ja) | 2012-06-05 | 2017-03-08 | Ｈｇｈ−ｘｔｅｎ融合タンパク質および成長ホルモン欠乏症の処置におけるその使用 |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US20140162949A1 (enExample) |
| EP (1) | EP2858664B1 (enExample) |
| JP (2) | JP2015520188A (enExample) |
| KR (1) | KR20150021072A (enExample) |
| CN (2) | CN107320719A (enExample) |
| AU (1) | AU2013272220A1 (enExample) |
| BR (1) | BR112014030404A2 (enExample) |
| CA (1) | CA2875827A1 (enExample) |
| DK (1) | DK2858664T3 (enExample) |
| ES (1) | ES2733220T3 (enExample) |
| HK (1) | HK1208629A1 (enExample) |
| IL (1) | IL236070A0 (enExample) |
| MX (1) | MX2014014927A (enExample) |
| NZ (1) | NZ702557A (enExample) |
| PH (1) | PH12014502738A1 (enExample) |
| SG (1) | SG11201408152VA (enExample) |
| WO (1) | WO2013184216A1 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7855279B2 (en) | 2005-09-27 | 2010-12-21 | Amunix Operating, Inc. | Unstructured recombinant polymers and uses thereof |
| DK3178835T3 (da) | 2009-02-03 | 2019-06-24 | Amunix Pharmaceuticals Inc | Forlængede rekombinante polypeptider og sammensætninger omfattende samme |
| US9849188B2 (en) | 2009-06-08 | 2017-12-26 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
| WO2014164568A1 (en) * | 2013-03-11 | 2014-10-09 | Amunix Operating Inc. | Treatment of pediatric growth hormone deficiency with human growth hormone analogues |
| IL319047A (en) | 2015-08-28 | 2025-04-01 | Amunix Operating Inc | Chimeric polypeptide composition and methods for its preparation and use |
| WO2017136583A1 (en) | 2016-02-02 | 2017-08-10 | Versartis, Inc. | Growth hormone treatment adherence system |
| EP3416677B1 (en) | 2016-02-17 | 2022-08-03 | Genexine, Inc. | Pharmaceutical composition comprising recombinant hgh for the treatment of growth hormone deficiency |
| WO2017142331A1 (en) * | 2016-02-17 | 2017-08-24 | Genexine, Inc. | Pharmaceutical composition comprising recombinant hgh for the treatment of growth hormone deficiency |
| WO2018022939A1 (en) * | 2016-07-27 | 2018-02-01 | Amunix Operating Inc. | Treatment of adult growth hormone deficiency with human growth hormone analogues |
| CN118105512A (zh) | 2016-08-30 | 2024-05-31 | 株式会社吉耐森 | 含有hGH融合蛋白的治疗生长激素缺乏症的药物组合物 |
| US10738338B2 (en) | 2016-10-18 | 2020-08-11 | The Research Foundation for the State University | Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate |
| KR20260039804A (ko) | 2017-12-21 | 2026-03-20 | 아뮤닉스 파마슈티컬스, 인크. | 유리 세그먼트 및 이것을 포함하는 결합 조성물 |
| MY204234A (en) | 2018-08-27 | 2024-08-16 | Regeneron Pharma | Use of raman spectroscopy in downstream purification |
| WO2021136223A1 (en) | 2019-12-31 | 2021-07-08 | Beijing Ql Biopharmaceutical Co., Ltd. | Fusion proteins of glp-1 and gdf15 and conjugates thereof |
| CN113728013B (zh) | 2020-01-11 | 2022-06-14 | 北京质肽生物医药科技有限公司 | Glp-1和fgf21的融合蛋白的缀合物 |
| CA3193453A1 (en) | 2020-09-30 | 2022-04-07 | Beijing Ql Biopharmaceutical Co., Ltd. | Polypeptide conjugates and methods of uses |
| CN116554343B (zh) * | 2022-01-30 | 2024-07-12 | 领诺(上海)医药科技有限公司 | 一种长效重组人生长激素及其应用 |
| EP4323413A4 (en) | 2022-03-30 | 2025-10-15 | Beijing Ql Biopharmaceutical Co Ltd | LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF |
| CN116003632B (zh) * | 2022-12-07 | 2026-02-24 | 北京大学 | 长效缓释型人重组生长激素融合蛋白及其药物组合物和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4898830A (en) | 1979-07-05 | 1990-02-06 | Genentech, Inc. | Human growth hormone DNA |
| US5206161A (en) | 1991-02-01 | 1993-04-27 | Genentech, Inc. | Human plasma carboxypeptidase B |
| EP0983303B1 (en) | 1997-05-21 | 2006-03-08 | Biovation Limited | Method for the production of non-immunogenic proteins |
| US6406632B1 (en) | 1998-04-03 | 2002-06-18 | Symyx Technologies, Inc. | Rapid characterization of polymers |
| GB9815157D0 (en) | 1998-07-13 | 1998-09-09 | Metron Designs Ltd | High resolution pulse width setting from relatively low frequency clocks |
| US20030228309A1 (en) | 2000-11-08 | 2003-12-11 | Theodora Salcedo | Antibodies that immunospecifically bind to TRAIL receptors |
| US6992174B2 (en) | 2001-03-30 | 2006-01-31 | Emd Lexigen Research Center Corp. | Reducing the immunogenicity of fusion proteins |
| US7294513B2 (en) | 2002-07-24 | 2007-11-13 | Wyatt Technology Corporation | Method and apparatus for characterizing solutions of small particles |
| US8680050B2 (en) * | 2009-02-03 | 2014-03-25 | Amunix Operating Inc. | Growth hormone polypeptides fused to extended recombinant polypeptides and methods of making and using same |
| US8703717B2 (en) * | 2009-02-03 | 2014-04-22 | Amunix Operating Inc. | Growth hormone polypeptides and methods of making and using same |
| DK3178835T3 (da) * | 2009-02-03 | 2019-06-24 | Amunix Pharmaceuticals Inc | Forlængede rekombinante polypeptider og sammensætninger omfattende samme |
| PE20121539A1 (es) * | 2009-06-08 | 2012-12-06 | Amunix Operating Inc | Polipeptidos de la hormona de crecimiento y metodos de preparacion |
-
2013
- 2013-03-14 CN CN201710596161.5A patent/CN107320719A/zh not_active Withdrawn
- 2013-03-14 ES ES13712656T patent/ES2733220T3/es active Active
- 2013-03-14 BR BR112014030404A patent/BR112014030404A2/pt not_active IP Right Cessation
- 2013-03-14 WO PCT/US2013/031673 patent/WO2013184216A1/en not_active Ceased
- 2013-03-14 HK HK15109368.8A patent/HK1208629A1/xx unknown
- 2013-03-14 JP JP2015516010A patent/JP2015520188A/ja active Pending
- 2013-03-14 SG SG11201408152VA patent/SG11201408152VA/en unknown
- 2013-03-14 CA CA2875827A patent/CA2875827A1/en not_active Abandoned
- 2013-03-14 NZ NZ702557A patent/NZ702557A/en not_active IP Right Cessation
- 2013-03-14 KR KR20147036167A patent/KR20150021072A/ko not_active Withdrawn
- 2013-03-14 AU AU2013272220A patent/AU2013272220A1/en not_active Abandoned
- 2013-03-14 EP EP13712656.1A patent/EP2858664B1/en active Active
- 2013-03-14 CN CN201380041556.9A patent/CN104519903A/zh active Pending
- 2013-03-14 US US13/829,369 patent/US20140162949A1/en not_active Abandoned
- 2013-03-14 MX MX2014014927A patent/MX2014014927A/es unknown
- 2013-03-14 DK DK13712656.1T patent/DK2858664T3/da active
-
2014
- 2014-12-04 IL IL236070A patent/IL236070A0/en unknown
- 2014-12-05 PH PH12014502738A patent/PH12014502738A1/en unknown
-
2017
- 2017-03-08 JP JP2017043512A patent/JP2017125051A/ja active Pending
- 2017-07-13 US US15/648,967 patent/US20180051063A1/en not_active Abandoned
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