JP2020532958A5 - - Google Patents
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- Publication number
- JP2020532958A5 JP2020532958A5 JP2020507679A JP2020507679A JP2020532958A5 JP 2020532958 A5 JP2020532958 A5 JP 2020532958A5 JP 2020507679 A JP2020507679 A JP 2020507679A JP 2020507679 A JP2020507679 A JP 2020507679A JP 2020532958 A5 JP2020532958 A5 JP 2020532958A5
- Authority
- JP
- Japan
- Prior art keywords
- ribonucleic acid
- acid compound
- cell
- compound according
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762544220P | 2017-08-11 | 2017-08-11 | |
| US62/544,220 | 2017-08-11 | ||
| US201862671604P | 2018-05-15 | 2018-05-15 | |
| US62/671,604 | 2018-05-15 | ||
| PCT/US2018/046343 WO2019033051A1 (en) | 2017-08-11 | 2018-08-10 | RNA APTAMERS AGAINST THE TRANSFERRIN RECEPTOR (TFR) |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020532958A JP2020532958A (ja) | 2020-11-19 |
| JP2020532958A5 true JP2020532958A5 (enExample) | 2021-09-16 |
| JP7382919B2 JP7382919B2 (ja) | 2023-11-17 |
Family
ID=65271776
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020507679A Active JP7382919B2 (ja) | 2017-08-11 | 2018-08-10 | トランスフェリン受容体（ＴｆＲ）に対するＲＮＡアプタマー |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11427826B2 (enExample) |
| EP (1) | EP3664814A4 (enExample) |
| JP (1) | JP7382919B2 (enExample) |
| KR (1) | KR20200068647A (enExample) |
| CN (2) | CN111542326B (enExample) |
| AU (1) | AU2018314236B2 (enExample) |
| CA (1) | CA3072575A1 (enExample) |
| WO (1) | WO2019033051A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3953473A1 (en) * | 2019-04-12 | 2022-02-16 | MiNA Therapeutics Limited | Sirt1-sarna compositions and methods of use |
| WO2020245198A1 (en) | 2019-06-04 | 2020-12-10 | Apterna Limited | APTAMERS AGAINST TRANSFERRIN RECEPTOR (TfR) |
| GB202019692D0 (en) | 2020-12-14 | 2021-01-27 | Apterna Ltd | Aptamer-sirna fusions |
| KR20240004937A (ko) | 2021-05-05 | 2024-01-11 | 이매틱스 바이오테크놀로지스 게엠베하 | Bma031 항원 결합 폴리펩타이드 |
| KR20260021596A (ko) | 2023-04-05 | 2026-02-13 | 아이오니스 파마수티컬즈, 인코포레이티드 | Pln 발현을 감소시키는 화합물 및 방법 |
| WO2026011165A1 (en) * | 2024-07-03 | 2026-01-08 | Creyon Bio, Inc. | Transferrin receptor (tfr) aptamers and use thereof |
| CN118879700B (zh) * | 2024-07-18 | 2025-11-07 | 四川大学 | 具有sirt1基因靶向激活功能的框架核酸药物的制备及其用途 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| US5235033A (en) | 1985-03-15 | 1993-08-10 | Anti-Gene Development Group | Alpha-morpholino ribonucleoside derivatives and polymers thereof |
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US6344321B1 (en) * | 1990-06-11 | 2002-02-05 | Gilead Sciences, Inc. | Nucleic acid ligands which bind to hepatocyte growth factor/scatter factor (HGF/SF) or its receptor c-met |
| US5830645A (en) | 1994-12-09 | 1998-11-03 | The Regents Of The University Of California | Comparative fluorescence hybridization to nucleic acid arrays |
| US20020142000A1 (en) | 1999-01-15 | 2002-10-03 | Digan Mary Ellen | Anti-CD3 immunotoxins and therapeutic uses therefor |
| AU2004242846A1 (en) | 2003-05-31 | 2004-12-09 | Micromet Ag | Pharmaceutical compositions comprising bispecific anti-CD3, anti-CD19 antibody constructs for the treatment of B-cell related disorders |
| JP2006089471A (ja) | 2004-08-26 | 2006-04-06 | National Institute Of Advanced Industrial & Technology | 癌の治療における抗モータリン２抗体と機能性核酸の使用 |
| AU2006291005A1 (en) | 2005-09-12 | 2007-03-22 | Novimmune S.A. | Anti-CD3 antibody formulations |
| WO2008119565A2 (en) | 2007-04-03 | 2008-10-09 | Micromet Ag | Cross-species-specific binding domain |
| WO2008119567A2 (en) | 2007-04-03 | 2008-10-09 | Micromet Ag | Cross-species-specific cd3-epsilon binding domain |
| PL2155788T3 (pl) | 2007-04-03 | 2013-02-28 | Amgen Res Munich Gmbh | Swoiste międzygatunkowe bispecyficzne czynniki wiążące |
| JP5142265B2 (ja) | 2007-05-28 | 2013-02-13 | 独立行政法人産業技術総合研究所 | 抗モータリン抗体のパラトープ及びエピトープ |
| WO2011071099A1 (ja) | 2009-12-10 | 2011-06-16 | 独立行政法人産業技術総合研究所 | 抗癌性抗モータリンペプチド抗体 |
| CA2817191A1 (en) * | 2010-10-08 | 2012-04-12 | Pal Saetrom | Short rna molecules |
| AU2013246419A1 (en) | 2012-04-10 | 2014-10-30 | City Of Hope | RNA aptamers for therapeutic and diagnostic delivery to pancreatic cancer cells |
| JP6636803B2 (ja) | 2013-02-05 | 2020-01-29 | エンクマフ エスアーエールエル | Ｂｃｍａに対する抗体の選択のための方法 |
| EP2976427A4 (en) | 2013-03-18 | 2017-02-22 | University Of The Witwatersrand, Johannesburg | Cd7 receptor aptamers |
| EP2789630A1 (en) | 2013-04-09 | 2014-10-15 | EngMab AG | Bispecific antibodies against CD3e and ROR1 |
| HK1214605A1 (zh) | 2013-04-19 | 2016-07-29 | Covagen Ag | 具有抗肿瘤活性的新颖的双特异性结合分子 |
| US20160326249A1 (en) | 2014-01-15 | 2016-11-10 | Zymeworks Inc. | Bi-specific cd3 and cd19 antigen-binding constructs |
| US9605266B2 (en) | 2014-07-16 | 2017-03-28 | City Of Hope | Cell-specific internalizing RNA aptamers against human CCR5 and uses therefore |
| WO2016019270A1 (en) | 2014-07-31 | 2016-02-04 | Academia Sinica | An antagonistic pd-1 aptamer and its applications in cancer therapy related applications |
| CN107106697B (zh) | 2014-10-15 | 2021-06-18 | 希望之城 | Pdgfr rna适体 |
| EP3206719B1 (en) * | 2014-10-15 | 2020-04-08 | City of Hope | Rna aptamers against transferrin receptor (tfr) |
| WO2016120325A1 (en) | 2015-01-27 | 2016-08-04 | Klinikum Rechts Der Isar Der Technischen Universität München | Quantitative assay for heat shock protein 70 (hsp70) protein in body fluids |
| JP6978317B2 (ja) | 2015-02-11 | 2021-12-08 | ディーキン・ユニバーシティー | ＥｐＣＡＭアプタマー及びそのコンジュゲート |
| WO2016161165A1 (en) | 2015-03-31 | 2016-10-06 | City Of Hope | Anti-cancer rna aptamers |
| US11219635B2 (en) | 2016-02-19 | 2022-01-11 | City Of Hope | Bi-specific aptamer |
| WO2019033050A1 (en) | 2017-08-11 | 2019-02-14 | City Of Hope | BISPECIFIC MOLECULE FOR BINDING TO ANTIGEN |
-
2018
- 2018-08-10 AU AU2018314236A patent/AU2018314236B2/en not_active Expired - Fee Related
- 2018-08-10 CA CA3072575A patent/CA3072575A1/en active Pending
- 2018-08-10 CN CN201880066428.2A patent/CN111542326B/zh active Active
- 2018-08-10 CN CN202410700060.8A patent/CN118931907A/zh active Pending
- 2018-08-10 US US16/637,679 patent/US11427826B2/en active Active
- 2018-08-10 KR KR1020207006810A patent/KR20200068647A/ko not_active Ceased
- 2018-08-10 WO PCT/US2018/046343 patent/WO2019033051A1/en not_active Ceased
- 2018-08-10 EP EP18844104.2A patent/EP3664814A4/en active Pending
- 2018-08-10 JP JP2020507679A patent/JP7382919B2/ja active Active
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