JP2022506687A5 - - Google Patents
Info
- Publication number
- JP2022506687A5 JP2022506687A5 JP2021524227A JP2021524227A JP2022506687A5 JP 2022506687 A5 JP2022506687 A5 JP 2022506687A5 JP 2021524227 A JP2021524227 A JP 2021524227A JP 2021524227 A JP2021524227 A JP 2021524227A JP 2022506687 A5 JP2022506687 A5 JP 2022506687A5
- Authority
- JP
- Japan
- Prior art keywords
- optionally substituted
- compound
- alkyl
- item
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2022166276A JP7429750B2 (ja) | 2018-11-06 | 2022-10-17 | ピリダジノン化合物およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862756553P | 2018-11-06 | 2018-11-06 | |
| US62/756,553 | 2018-11-06 | ||
| PCT/US2019/060157 WO2020097266A1 (en) | 2018-11-06 | 2019-11-06 | Pyridazinone compounds and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022166276A Division JP7429750B2 (ja) | 2018-11-06 | 2022-10-17 | ピリダジノン化合物およびその使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022506687A JP2022506687A (ja) | 2022-01-17 |
| JP2022506687A5 true JP2022506687A5 (https=) | 2022-05-17 |
| JP7162132B2 JP7162132B2 (ja) | 2022-10-27 |
Family
ID=69160036
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021524227A Active JP7162132B2 (ja) | 2018-11-06 | 2019-11-06 | ピリダジノン化合物およびその使用 |
| JP2022166276A Active JP7429750B2 (ja) | 2018-11-06 | 2022-10-17 | ピリダジノン化合物およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2022166276A Active JP7429750B2 (ja) | 2018-11-06 | 2022-10-17 | ピリダジノン化合物およびその使用 |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US11091464B2 (https=) |
| EP (2) | EP4248973A3 (https=) |
| JP (2) | JP7162132B2 (https=) |
| KR (1) | KR20210100094A (https=) |
| CN (2) | CN120737085A (https=) |
| AU (1) | AU2019376065B2 (https=) |
| BR (1) | BR112021008905A2 (https=) |
| CA (1) | CA3118934A1 (https=) |
| DK (1) | DK3877376T3 (https=) |
| EA (1) | EA202191084A1 (https=) |
| ES (1) | ES2958954T3 (https=) |
| FI (1) | FI3877376T3 (https=) |
| HR (1) | HRP20231389T1 (https=) |
| HU (1) | HUE063586T2 (https=) |
| IL (1) | IL282998A (https=) |
| LT (1) | LT3877376T (https=) |
| MX (2) | MX2021005350A (https=) |
| PL (1) | PL3877376T3 (https=) |
| PT (1) | PT3877376T (https=) |
| RS (1) | RS64828B1 (https=) |
| SG (1) | SG11202104713RA (https=) |
| SI (1) | SI3877376T1 (https=) |
| SM (1) | SMT202300355T1 (https=) |
| WO (1) | WO2020097266A1 (https=) |
| ZA (1) | ZA202103260B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2021514010A (ja) * | 2018-02-20 | 2021-06-03 | エッジワイズ セラピューティクス, インコーポレイテッド | 運動障害を処置するための方法および組成物 |
| HU231285B1 (hu) | 2018-04-18 | 2022-08-28 | Printnet Kereskedelmi És Szolgáltató Kft. | A miozin-2-izoformákat szelektíven gátló, gyógyászatilag hatásos vegyületek |
| EP3877052B1 (en) | 2018-11-06 | 2023-08-16 | Edgewise Therapeutics, Inc. | Pyridazinone compounds and uses thereof |
| WO2020097258A1 (en) | 2018-11-06 | 2020-05-14 | Edgewise Therapeutics, Inc. | Pyridazinone compounds and uses thereof |
| ES2958954T3 (es) | 2018-11-06 | 2024-02-16 | Edgewise Therapeutics Inc | Compuestos de piridazinona y usos de los mismos |
| WO2021231615A1 (en) * | 2020-05-13 | 2021-11-18 | Edgewise Therapeutics, Inc. | Substituted pyridazinone for use in the treatment of neuromuscular diseases |
| EP4149620B1 (en) * | 2020-05-13 | 2024-10-23 | Edgewise Therapeutics, Inc. | Pyridazinone compounds for the treatment of neuromuscular diseases |
| JP7758687B2 (ja) * | 2020-05-13 | 2025-10-22 | エッジワイズ セラピューティクス, インコーポレイテッド | 神経筋疾患の処置のためのピリダジノン化合物 |
| WO2021231630A1 (en) * | 2020-05-13 | 2021-11-18 | Edgewise Therapeutics, Inc. | Substituted pyridazinone for use in the treatment of neuromuscular diseases |
| WO2021231546A1 (en) * | 2020-05-13 | 2021-11-18 | Edgewise Therapeutics, Inc. | Substituted pyridazinone for use in the treatment of neuromuscular diseases |
| EP4433473A1 (en) * | 2021-11-17 | 2024-09-25 | Edgewise Therapeutics, Inc. | Pyridazinone compounds and uses thereof |
| EP4522599A1 (en) * | 2022-05-11 | 2025-03-19 | Edgewise Therapeutics, Inc. | Methods of manufacturing pyridazinone compounds |
| JP2025530218A (ja) | 2022-09-09 | 2025-09-11 | エッジワイズ セラピューティクス, インコーポレイテッド | 神経筋の状態の処置のためのピリダジノン組成物 |
| JP2026501712A (ja) * | 2023-01-04 | 2026-01-16 | シーザン ハイスーク ファーマシューティカル カンパニー リミテッド | ピリダジノンヘテロ環化合物Myosin II阻害剤及びその用途 |
| WO2025167826A1 (zh) * | 2024-02-06 | 2025-08-14 | 西藏海思科制药有限公司 | 三环化合物作为Myosin II抑制剂及其用途 |
| WO2025242154A1 (zh) * | 2024-05-23 | 2025-11-27 | 西藏海思科制药有限公司 | 哒嗪酮衍生物及其用途 |
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| JPS6140270A (ja) | 1984-08-01 | 1986-02-26 | Morishita Seiyaku Kk | ピリダジノン誘導体 |
| DD286354A5 (de) | 1989-08-08 | 1991-01-24 | Karl-Marx-Universitaet Leipzig,De | Verfahren zur herstellung substituierter 2-carbamoyl-methyl-4-phenyl-1,2,5,6-tetrahydro- und 1,2-dihydro-1-oxo-pyridazine |
| DE69131268T2 (de) | 1990-09-21 | 1999-12-30 | Rohm And Haas Co., Philadelphia | Dihydropyridazinone und Pyridazinone als Fungizide |
| US6334997B1 (en) | 1994-03-25 | 2002-01-01 | Isotechnika, Inc. | Method of using deuterated calcium channel blockers |
| ES2293638T3 (es) | 1994-03-25 | 2008-03-16 | Isotechnika, Inc. | Mejora de la eficacia de farmacos por deuteracion. |
| IL118631A (en) | 1995-06-27 | 2002-05-23 | Tanabe Seiyaku Co | History of pyridazinone and processes for their preparation |
| DE19629817A1 (de) | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Imino-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| NZ522882A (en) | 2000-06-05 | 2004-07-30 | Altana Pharma Bv | Pyridazinone compounds effective as beta-2-adrenoreceptor agonists as well as PDE4-inhibitors |
| WO2004022540A2 (en) | 2002-09-06 | 2004-03-18 | Fujisawa Pharmaceutical Co., Ltd. | Pyridazinone and pyridone derivatives as adenosine antagonists |
| BRPI0407519A (pt) | 2003-03-07 | 2006-02-14 | Kowa Co | derivados de benzofurano |
| WO2006095666A1 (ja) | 2005-03-07 | 2006-09-14 | Kyorin Pharmaceutical Co., Ltd. | ピラゾロピリジン-4-イルピリダジノン誘導体とその付加塩及びそれらを有効成分とするpde阻害剤 |
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| MX2009008531A (es) | 2007-02-16 | 2009-08-26 | Amgen Inc | Cetonas de heterociclilo que contienen nitrogeno y su uso como inhibidores de c-met. |
| DE102007025718A1 (de) | 2007-06-01 | 2008-12-04 | Merck Patent Gmbh | Pyridazinonderivate |
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| WO2012021707A2 (en) | 2010-08-11 | 2012-02-16 | The Regents Of The University Of California | Premature-termination-codons readthrough compounds |
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| WO2014031928A2 (en) | 2012-08-24 | 2014-02-27 | Philip Jones | Heterocyclic modulators of hif activity for treatment of disease |
| US9566310B2 (en) * | 2012-09-10 | 2017-02-14 | Board Of Regents Of The Nevada System Of Higher Education On Behalf Of The University Of Nevada, Reno | Methods of treating muscular dystrophy |
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| EP4685140A1 (en) | 2018-06-04 | 2026-01-28 | Ohio State Innovation Foundation | Eaat2 activators and methods of using thereof |
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| CN108947912B (zh) | 2018-07-31 | 2021-10-01 | 中国人民解放军总医院 | 一种靶向Neddylation通路的抗肿瘤化合物 |
| ES2958954T3 (es) | 2018-11-06 | 2024-02-16 | Edgewise Therapeutics Inc | Compuestos de piridazinona y usos de los mismos |
| EP3877052B1 (en) | 2018-11-06 | 2023-08-16 | Edgewise Therapeutics, Inc. | Pyridazinone compounds and uses thereof |
| WO2020097258A1 (en) | 2018-11-06 | 2020-05-14 | Edgewise Therapeutics, Inc. | Pyridazinone compounds and uses thereof |
| WO2021231546A1 (en) | 2020-05-13 | 2021-11-18 | Edgewise Therapeutics, Inc. | Substituted pyridazinone for use in the treatment of neuromuscular diseases |
| JP7758687B2 (ja) | 2020-05-13 | 2025-10-22 | エッジワイズ セラピューティクス, インコーポレイテッド | 神経筋疾患の処置のためのピリダジノン化合物 |
| WO2021231630A1 (en) | 2020-05-13 | 2021-11-18 | Edgewise Therapeutics, Inc. | Substituted pyridazinone for use in the treatment of neuromuscular diseases |
| EP4149620B1 (en) | 2020-05-13 | 2024-10-23 | Edgewise Therapeutics, Inc. | Pyridazinone compounds for the treatment of neuromuscular diseases |
| WO2021231615A1 (en) | 2020-05-13 | 2021-11-18 | Edgewise Therapeutics, Inc. | Substituted pyridazinone for use in the treatment of neuromuscular diseases |
| EP4433473A1 (en) | 2021-11-17 | 2024-09-25 | Edgewise Therapeutics, Inc. | Pyridazinone compounds and uses thereof |
| EP4522599A1 (en) | 2022-05-11 | 2025-03-19 | Edgewise Therapeutics, Inc. | Methods of manufacturing pyridazinone compounds |
| JP2025530218A (ja) | 2022-09-09 | 2025-09-11 | エッジワイズ セラピューティクス, インコーポレイテッド | 神経筋の状態の処置のためのピリダジノン組成物 |
-
2019
- 2019-11-06 ES ES19835997T patent/ES2958954T3/es active Active
- 2019-11-06 MX MX2021005350A patent/MX2021005350A/es unknown
- 2019-11-06 CN CN202510831147.3A patent/CN120737085A/zh active Pending
- 2019-11-06 PT PT198359978T patent/PT3877376T/pt unknown
- 2019-11-06 EP EP23189000.5A patent/EP4248973A3/en active Pending
- 2019-11-06 FI FIEP19835997.8T patent/FI3877376T3/fi active
- 2019-11-06 SG SG11202104713RA patent/SG11202104713RA/en unknown
- 2019-11-06 SI SI201930610T patent/SI3877376T1/sl unknown
- 2019-11-06 HU HUE19835997A patent/HUE063586T2/hu unknown
- 2019-11-06 EP EP19835997.8A patent/EP3877376B1/en active Active
- 2019-11-06 PL PL19835997.8T patent/PL3877376T3/pl unknown
- 2019-11-06 AU AU2019376065A patent/AU2019376065B2/en active Active
- 2019-11-06 DK DK19835997.8T patent/DK3877376T3/da active
- 2019-11-06 KR KR1020217016684A patent/KR20210100094A/ko active Pending
- 2019-11-06 JP JP2021524227A patent/JP7162132B2/ja active Active
- 2019-11-06 EA EA202191084A patent/EA202191084A1/ru unknown
- 2019-11-06 LT LTEPPCT/US2019/060157T patent/LT3877376T/lt unknown
- 2019-11-06 BR BR112021008905-5A patent/BR112021008905A2/pt unknown
- 2019-11-06 WO PCT/US2019/060157 patent/WO2020097266A1/en not_active Ceased
- 2019-11-06 SM SM20230355T patent/SMT202300355T1/it unknown
- 2019-11-06 CA CA3118934A patent/CA3118934A1/en active Pending
- 2019-11-06 HR HRP20231389TT patent/HRP20231389T1/hr unknown
- 2019-11-06 CN CN201980088114.7A patent/CN113272291B/zh active Active
- 2019-11-06 RS RS20231080A patent/RS64828B1/sr unknown
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2020
- 2020-11-03 US US17/088,469 patent/US11091464B2/en active Active
-
2021
- 2021-05-06 IL IL282998A patent/IL282998A/en unknown
- 2021-05-06 MX MX2024004531A patent/MX2024004531A/es unknown
- 2021-05-13 ZA ZA2021/03260A patent/ZA202103260B/en unknown
- 2021-06-11 US US17/345,909 patent/US12012395B2/en active Active
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2022
- 2022-10-17 JP JP2022166276A patent/JP7429750B2/ja active Active
-
2023
- 2023-09-01 US US18/460,464 patent/US12240831B2/en active Active
-
2024
- 2024-12-13 US US18/981,327 patent/US20250223278A1/en active Pending
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