JP2022506445A5 - - Google Patents
Info
- Publication number
- JP2022506445A5 JP2022506445A5 JP2021523833A JP2021523833A JP2022506445A5 JP 2022506445 A5 JP2022506445 A5 JP 2022506445A5 JP 2021523833 A JP2021523833 A JP 2021523833A JP 2021523833 A JP2021523833 A JP 2021523833A JP 2022506445 A5 JP2022506445 A5 JP 2022506445A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- groups
- alkyl
- independently
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862752414P | 2018-10-30 | 2018-10-30 | |
| US62/752,414 | 2018-10-30 | ||
| PCT/US2019/058268 WO2020092196A1 (en) | 2018-10-30 | 2019-10-28 | Amide-substituted heterocyclic compounds for the treatment of conditions related to the modulation of il-12, il-23 and/or ifn-alpha |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022506445A JP2022506445A (ja) | 2022-01-17 |
| JP2022506445A5 true JP2022506445A5 (enExample) | 2022-11-07 |
| JP7489381B2 JP7489381B2 (ja) | 2024-05-23 |
Family
ID=68582450
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021523833A Active JP7489381B2 (ja) | 2018-10-30 | 2019-10-28 | Ｉｌ－１２、ｉｌ－２３および／またはｉｆｎアルファの調節に関連する疾患を治療するためのアミド置換ヘテロ環化合物 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12240840B2 (enExample) |
| EP (1) | EP3873892A1 (enExample) |
| JP (1) | JP7489381B2 (enExample) |
| KR (1) | KR102858043B1 (enExample) |
| CN (1) | CN113227071B (enExample) |
| AU (1) | AU2019373203B2 (enExample) |
| BR (1) | BR112021007861A2 (enExample) |
| CA (1) | CA3118094A1 (enExample) |
| EA (1) | EA202191142A1 (enExample) |
| IL (1) | IL282840B2 (enExample) |
| MX (1) | MX2021004562A (enExample) |
| SG (1) | SG11202104307VA (enExample) |
| WO (1) | WO2020092196A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4118081A1 (en) | 2020-03-27 | 2023-01-18 | Landos Biopharma, Inc. | Plxdc2 ligands |
| KR20230004771A (ko) | 2020-04-28 | 2023-01-06 | 브리스톨-마이어스 스큅 컴퍼니 | Il-12, il-23 및/또는 ifn알파 조정제로서의 치환된 n-(메틸-d3)피리다진-3-카르복스아미드 또는 n-(메틸-d3)-니코틴아미드 화합물 |
| EP4146205A4 (en) | 2020-05-05 | 2024-05-29 | Nuvalent, Inc. | HETEROAROMATIC MACROCYCLIC ETHERS AS CHEMOTHERAPEUTIC AGENTS |
| IL297832A (en) | 2020-05-05 | 2023-01-01 | Nuvalent Inc | Macrocyclic heteroaromatic chemotherapeutic agents |
| CN113773262B (zh) * | 2020-06-09 | 2024-08-09 | 江苏先声药业有限公司 | 哒嗪类化合物 |
| CN114057651B (zh) * | 2020-07-31 | 2025-05-27 | 正大天晴药业集团股份有限公司 | 含酰胺基的tyk2抑制剂化合物 |
| CN116547276A (zh) * | 2020-12-08 | 2023-08-04 | 正大天晴药业集团股份有限公司 | 含酰胺基和杂环烷基的tyk2抑制剂化合物 |
| US12492184B2 (en) | 2020-12-22 | 2025-12-09 | InventisBio Co., Ltd. | Heteroaryl compounds, preparation methods and uses thereof |
| TW202233600A (zh) * | 2021-02-06 | 2022-09-01 | 大陸商正大天晴藥業集團股份有限公司 | 含聯環的ｔｙｋ２抑制劑化合物、藥物組合物及其用途 |
| CN114907326B (zh) * | 2021-02-06 | 2025-02-18 | 正大天晴药业集团股份有限公司 | 含酰胺基和联环的tyk2抑制剂化合物 |
| CA3213816A1 (en) * | 2021-03-16 | 2022-09-22 | Anrui Biomedical Technology (Guangzhou) Co., Ltd. | Amino heteroaryl compounds and compositions |
| JP2024518791A (ja) * | 2021-05-14 | 2024-05-02 | ブリストル－マイヤーズ スクイブ カンパニー | 置換ヘテロ環化合物 |
| US11884650B2 (en) | 2021-05-14 | 2024-01-30 | Bristol-Myers Squibb Company | Substituted heterocyclic compounds |
| US20240317718A1 (en) * | 2021-05-14 | 2024-09-26 | Bristol-Myers Squibb Company | Substituted heterocyclic compounds |
| WO2022253333A1 (zh) * | 2021-06-02 | 2022-12-08 | 南京明德新药研发有限公司 | 酰胺类化合物及其应用 |
| WO2022253335A1 (zh) * | 2021-06-02 | 2022-12-08 | 南京明德新药研发有限公司 | 含磺酰基的芳基类化合物及其应用 |
| CN115466289A (zh) * | 2021-06-11 | 2022-12-13 | 爱科诺生物医药(香港)有限公司 | 具有tyk2抑制活性的化合物，包含其的药物组合物，及其应用 |
| CA3223641A1 (en) * | 2021-06-22 | 2022-12-29 | Wenyuan Qian | Sulfoximine compound and use thereof |
| JP2024535865A (ja) * | 2021-07-15 | 2024-10-02 | メッドシャイン ディスカバリー インコーポレイテッド | 硫黄／リン含有アリール系化合物及びその使用 |
| WO2023027948A1 (en) * | 2021-08-21 | 2023-03-02 | Relay Therapeutics, Inc. | Jak2 inhibitors and methods of use thereof |
| TW202320768A (zh) | 2021-10-01 | 2023-06-01 | 美商努法倫特公司 | 雜芳族大環醚化合物之固體形式、醫藥組成物及製備 |
| EP4423086A1 (en) | 2021-10-25 | 2024-09-04 | Kymera Therapeutics, Inc. | Tyk2 degraders and uses thereof |
| AU2022412835A1 (en) | 2021-12-16 | 2024-06-20 | Lynk Pharmaceuticals Co. Ltd. | Tyk2 inhibitors and compositions and methods thereof |
| CN116283928A (zh) * | 2021-12-20 | 2023-06-23 | 艾立康药业股份有限公司 | 一种哒嗪类化合物、其制备方法和应用 |
| WO2023213308A1 (zh) * | 2022-05-05 | 2023-11-09 | 苏州隆博泰药业有限公司 | 酰胺取代的杂环化合物及其医药用途 |
| CN119894879A (zh) * | 2022-07-14 | 2025-04-25 | 渤健马萨诸塞州股份有限公司 | 酪氨酸激酶2抑制剂及其用途 |
| WO2024044486A1 (en) * | 2022-08-22 | 2024-02-29 | Ajax Therapeutics, Inc. | Jak2 inhibitor compounds |
| CN120152968A (zh) * | 2022-11-08 | 2025-06-13 | 百时美施贵宝公司 | 取代的杂环化合物 |
| CN120239699A (zh) * | 2022-12-22 | 2025-07-01 | 祐森健恒生物医药（上海）有限公司 | 一种吡啶多取代化合物的盐型、晶型及其制备方法 |
| WO2024174229A1 (en) * | 2023-02-24 | 2024-08-29 | Anrui Biomedical Technology (Guangzhou) Co., Ltd. | Covalent binding compounds and compositions |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102233252B1 (ko) * | 2012-11-08 | 2021-03-26 | 브리스톨-마이어스 스큅 컴퍼니 | ＩＬ-12, ＩＬ-23 및/또는 ＩＦＮα 반응의 조절제로서 유용한 알킬-아미드-치환된 피리딜 화합물 |
| LT3495358T (lt) * | 2012-11-08 | 2022-05-25 | Bristol-Myers Squibb Company | Amidais pakeisti heterocikliniai junginiai, naudingi kaip il-12, il-23 ir (arba) ifn alfa atsako moduliatoriai |
| TWI582077B (zh) * | 2013-11-07 | 2017-05-11 | 必治妥美雅史谷比公司 | 作爲ＩＬ－１２、ＩＬ－２３及／或ＩＦＮα反應調節劑之經烷基－醯胺取代之吡啶化合物 |
| CN111936486B (zh) * | 2018-03-22 | 2023-09-22 | 百时美施贵宝公司 | 用作IL-12、IL-23和/或IFNα响应的调节剂的包含吡啶的杂环化合物 |
| PE20250262A1 (es) * | 2021-05-14 | 2025-01-29 | Bristol Myers Squibb Co | Compuestos heterociclicos sustituidos |
-
2019
- 2019-10-28 AU AU2019373203A patent/AU2019373203B2/en active Active
- 2019-10-28 BR BR112021007861-4A patent/BR112021007861A2/pt unknown
- 2019-10-28 EA EA202191142A patent/EA202191142A1/ru unknown
- 2019-10-28 SG SG11202104307VA patent/SG11202104307VA/en unknown
- 2019-10-28 JP JP2021523833A patent/JP7489381B2/ja active Active
- 2019-10-28 US US17/289,269 patent/US12240840B2/en active Active
- 2019-10-28 MX MX2021004562A patent/MX2021004562A/es unknown
- 2019-10-28 WO PCT/US2019/058268 patent/WO2020092196A1/en not_active Ceased
- 2019-10-28 CN CN201980085746.8A patent/CN113227071B/zh active Active
- 2019-10-28 IL IL282840A patent/IL282840B2/en unknown
- 2019-10-28 CA CA3118094A patent/CA3118094A1/en active Pending
- 2019-10-28 EP EP19805033.8A patent/EP3873892A1/en active Pending
- 2019-10-28 KR KR1020217016043A patent/KR102858043B1/ko active Active
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