JP2022505877A5 - - Google Patents
Info
- Publication number
- JP2022505877A5 JP2022505877A5 JP2021522959A JP2021522959A JP2022505877A5 JP 2022505877 A5 JP2022505877 A5 JP 2022505877A5 JP 2021522959 A JP2021522959 A JP 2021522959A JP 2021522959 A JP2021522959 A JP 2021522959A JP 2022505877 A5 JP2022505877 A5 JP 2022505877A5
- Authority
- JP
- Japan
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18202986.8 | 2018-10-26 | ||
| EP18202986 | 2018-10-26 | ||
| PCT/EP2019/079358 WO2020084162A1 (en) | 2018-10-26 | 2019-10-28 | Liver-specific nucleic acid regulatory elements and methods and use thereof |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022505877A JP2022505877A (ja) | 2022-01-14 |
| JPWO2020084162A5 JPWO2020084162A5 (https=) | 2022-11-08 |
| JP2022505877A5 true JP2022505877A5 (https=) | 2022-11-08 |
| JP7529286B2 JP7529286B2 (ja) | 2024-08-06 |
Family
ID=64316267
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021522959A Active JP7529286B2 (ja) | 2018-10-26 | 2019-10-28 | 肝特異的核酸調節エレメント並びにその方法及び使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20210403948A1 (https=) |
| EP (1) | EP3870237A1 (https=) |
| JP (1) | JP7529286B2 (https=) |
| CN (1) | CN112912112B (https=) |
| WO (1) | WO2020084162A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3823985A1 (en) | 2018-07-16 | 2021-05-26 | Baxalta Incorporated | Gene therapy of hemophilia a using viral vectors encoding recombinant fviii variants with increased expression |
| GB201813528D0 (en) | 2018-08-20 | 2018-10-03 | Ucl Business Plc | Factor IX encoding nucleotides |
| TWI851647B (zh) * | 2019-01-16 | 2024-08-11 | 日商武田藥品工業股份有限公司 | 用於a型血友病基因治療之編碼表現增加之重組fviii變異體的病毒載體 |
| CN110791502B (zh) * | 2019-12-04 | 2022-07-08 | 陕西理工大学 | 人源rbp4启动子片段及其应用 |
| TW202208632A (zh) | 2020-05-27 | 2022-03-01 | 美商同源醫藥公司 | 用於恢復ｐａｈ基因功能的腺相關病毒組成物及其使用方法 |
| AU2022242921A1 (en) * | 2021-03-25 | 2023-10-19 | The Johns Hopkins University | Hydrodynamic gene delivery |
| JP2025534900A (ja) * | 2022-10-08 | 2025-10-21 | リンイ バイオテック カンパニー リミテッド | 遺伝子発現を増強するためのコンストラクト |
| WO2025092951A1 (en) * | 2023-11-03 | 2025-05-08 | Shanghai Vitalgen Biopharma Co., Ltd. | Recombinant adeno-associated viral vectors for treating fabry disease |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7351813B2 (en) | 2000-06-20 | 2008-04-01 | The Board Of Trustees Of The Leland Stanford Junior University | Liver-specific gene expression cassettes, and methods of use |
| US20070161031A1 (en) * | 2005-12-16 | 2007-07-12 | The Board Of Trustees Of The Leland Stanford Junior University | Functional arrays for high throughput characterization of gene expression regulatory elements |
| US20090018031A1 (en) * | 2006-12-07 | 2009-01-15 | Switchgear Genomics | Transcriptional regulatory elements of biological pathways tools, and methods |
| CN102618536B (zh) * | 2008-02-14 | 2013-10-16 | 财团法人牧岩生命工学研究所 | 适于表达用于基因治疗的编码序列的表达载体 |
| EP4154903A1 (en) | 2008-04-22 | 2023-03-29 | Vib Vzw | Liver-specific nucleic acid regulatory elements and methods and use thereof |
| US20100323376A1 (en) * | 2009-06-17 | 2010-12-23 | Maine Standards Company, Llc | Method for Measuring Lipoprotein-Specific Apolipoproteins |
| GB0911870D0 (en) | 2009-07-08 | 2009-08-19 | Ucl Business Plc | Optimised coding sequence and promoter |
| US8815779B2 (en) * | 2009-09-16 | 2014-08-26 | SwitchGear Genomics, Inc. | Transcription biomarkers of biological responses and methods |
| WO2011051450A1 (en) | 2009-10-29 | 2011-05-05 | Vib Vzw | Cardiac-specific nucleic acid regulatory elements and methods and use thereof |
| US20150141320A1 (en) * | 2012-05-16 | 2015-05-21 | Rana Therapeutics, Inc. | Compositions and methods for modulating gene expression |
| WO2013186398A1 (en) * | 2012-06-15 | 2013-12-19 | Fondazione Telethon | Tfeb for use in treating obesity or metabolic syndrome |
| EP2911687B1 (en) | 2012-10-26 | 2019-02-13 | Vrije Universiteit Brussel | Vector for liver-directed gene therapy of hemophilia and methods and use thereof |
| KR101429696B1 (ko) * | 2012-11-21 | 2014-08-13 | 국립암센터 | 안전성 및 항암활성이 증가된 재조합 아데노바이러스 및 이의 용도 |
| EP3270944B1 (en) | 2015-03-17 | 2019-10-23 | Vrije Universiteit Brussel | Optimized liver-specific expression systems for fviii and fix |
| CA3002524A1 (en) * | 2015-10-28 | 2017-05-04 | Sangamo Therapeutics, Inc. | Liver-specific constructs, factor viii expression cassettes and methods of use thereof |
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2019
- 2019-10-28 US US17/288,425 patent/US20210403948A1/en active Pending
- 2019-10-28 EP EP19789570.9A patent/EP3870237A1/en active Pending
- 2019-10-28 WO PCT/EP2019/079358 patent/WO2020084162A1/en not_active Ceased
- 2019-10-28 CN CN201980070613.3A patent/CN112912112B/zh active Active
- 2019-10-28 JP JP2021522959A patent/JP7529286B2/ja active Active