JP2022504153A5 - - Google Patents

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Publication number
JP2022504153A5
JP2022504153A5 JP2021518432A JP2021518432A JP2022504153A5 JP 2022504153 A5 JP2022504153 A5 JP 2022504153A5 JP 2021518432 A JP2021518432 A JP 2021518432A JP 2021518432 A JP2021518432 A JP 2021518432A JP 2022504153 A5 JP2022504153 A5 JP 2022504153A5
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JP
Japan
Prior art keywords
insulin
egf
gaqp
desb30
gglu
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021518432A
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English (en)
Japanese (ja)
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JP2022504153A (ja
JP7434299B2 (ja
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Application filed filed Critical
Priority claimed from PCT/EP2019/076889 external-priority patent/WO2020070276A1/en
Publication of JP2022504153A publication Critical patent/JP2022504153A/ja
Publication of JP2022504153A5 publication Critical patent/JP2022504153A5/ja
Application granted granted Critical
Publication of JP7434299B2 publication Critical patent/JP7434299B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021518432A 2018-10-05 2019-10-04 インスリンペプチドおよびegf(a)ペプチドを含む二官能性化合物 Active JP7434299B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18198892 2018-10-05
EP18198892.4 2018-10-05
PCT/EP2019/076889 WO2020070276A1 (en) 2018-10-05 2019-10-04 Bifunctional compounds comprising insulin peptides and egf(a) peptides

Publications (3)

Publication Number Publication Date
JP2022504153A JP2022504153A (ja) 2022-01-13
JP2022504153A5 true JP2022504153A5 (cg-RX-API-DMAC10.html) 2022-10-12
JP7434299B2 JP7434299B2 (ja) 2024-02-20

Family

ID=64017248

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021518432A Active JP7434299B2 (ja) 2018-10-05 2019-10-04 インスリンペプチドおよびegf(a)ペプチドを含む二官能性化合物

Country Status (8)

Country Link
US (1) US11649269B2 (cg-RX-API-DMAC10.html)
EP (1) EP3861017A1 (cg-RX-API-DMAC10.html)
JP (1) JP7434299B2 (cg-RX-API-DMAC10.html)
CN (1) CN112789289A (cg-RX-API-DMAC10.html)
AR (1) AR116605A1 (cg-RX-API-DMAC10.html)
MA (1) MA53809A (cg-RX-API-DMAC10.html)
TW (1) TW202028229A (cg-RX-API-DMAC10.html)
WO (1) WO2020070276A1 (cg-RX-API-DMAC10.html)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3939605A1 (en) 2016-12-09 2022-01-19 Akston Biosciences Corporation Insulin-fc fusions and methods of use
US11267862B2 (en) 2018-06-29 2022-03-08 Akston Biosciences Corporation Ultra-long acting insulin-Fc fusion proteins and methods of use
HUE062719T2 (hu) 2018-06-29 2023-11-28 Akston Biosciences Corp Ultra-hosszú hatású inzulin-FC fúziós fehérjék és az alkalmazási eljárások
KR102865175B1 (ko) 2019-12-19 2025-09-30 악스톤 바이오사이언시스 코퍼레이션 초-장기 작용 인슐린-fc 융합 단백질 및 사용 방법
US11186623B2 (en) 2019-12-24 2021-11-30 Akston Bioscience Corporation Ultra-long acting insulin-Fc fusion proteins and methods of use
US11192930B2 (en) 2020-04-10 2021-12-07 Askton Bioscences Corporation Ultra-long acting insulin-Fc fusion protein and methods of use
LT3972987T (lt) 2020-04-10 2023-09-25 Akston Biosciences Corporation Antigenui specifinė imunoterapija, skirta sulietiems covid-19 baltymams ir naudojimo būdai
US11198719B2 (en) 2020-04-29 2021-12-14 Akston Biosciences Corporation Ultra-long acting insulin-Fc fusion protein and methods of use
CA3193453A1 (en) 2020-09-30 2022-04-07 Beijing Ql Biopharmaceutical Co., Ltd. Polypeptide conjugates and methods of uses
US11667689B2 (en) 2021-07-23 2023-06-06 Akston Biosciences Corporation Insulin-Fc fusion proteins and methods of use to treat cancer
EP4323413A4 (en) 2022-03-30 2025-10-15 Beijing Ql Biopharmaceutical Co Ltd LIQUID PHARMACEUTICAL COMPOSITIONS OF POLYPEPTIDE CONJUGATES AND METHODS OF USE THEREOF
CN115850385B (zh) * 2022-07-04 2023-08-11 北京惠之衡生物科技有限公司 一种促表达肽及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009022006A1 (en) 2007-08-15 2009-02-19 Novo Nordisk A/S Insulins with an acyl moiety comprising repeating units of alkylene glycol containing amino acids
HUE032284T2 (en) 2008-03-18 2017-09-28 Novo Nordisk As Protease-stabilized, acylated insulin analogues
EP2296694B1 (en) 2008-04-23 2015-08-05 Amgen Inc. Neutralizing proprotein convertase subtilisin kexin type 9 (pcsk9) variants and uses thereof
GB201005005D0 (en) 2010-03-25 2010-05-12 Angeletti P Ist Richerche Bio New vaccine
KR20140041747A (ko) 2011-06-20 2014-04-04 제넨테크, 인크. Pcsk9-결합 폴리펩티드 및 사용 방법
BR112016017402A2 (pt) 2014-02-21 2017-10-17 Medimmune Ltd fusões anti-pcsk9~glp-1 e métodos para uso
CN104558199B (zh) 2014-09-05 2018-07-06 成都康弘生物科技有限公司 一种治疗高胆固醇血症的融合蛋白制备及其用途
WO2016164762A1 (en) 2015-04-08 2016-10-13 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor egf-a and intracellular domain mutants and methods of using the same
BR112018002416A2 (pt) 2015-08-25 2018-09-18 Novo Nordisk As derivados de insulina e seus usos médicos
RU2747877C2 (ru) 2016-01-13 2021-05-17 Ново Нордиск А/С Аналоги эфр(а) с заместителями - жирными кислотами

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