|
US5919676A
(en)
|
1993-06-24 |
1999-07-06 |
Advec, Inc. |
Adenoviral vector system comprising Cre-loxP recombination
|
|
US6379943B1
(en)
|
1999-03-05 |
2002-04-30 |
Merck & Co., Inc. |
High-efficiency Cre/loxp based system for construction of adenovirus vectors
|
|
US6228646B1
(en)
|
1996-03-07 |
2001-05-08 |
The Regents Of The University Of California |
Helper-free, totally defective adenovirus for gene therapy
|
|
EP1696036B1
(en)
|
1996-09-06 |
2010-04-21 |
The Trustees of The University of Pennsylvania |
Use of recombinant adeno-associated virus in the manufacture of a medicament for gene therapy via muscle cells
|
|
WO1998010086A1
(en)
|
1996-09-06 |
1998-03-12 |
Trustees Of The University Of Pennsylvania |
Methods using cre-lox for production of recombinant adeno-associated viruses
|
|
US6566118B1
(en)
|
1997-09-05 |
2003-05-20 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
|
DE19933719A1
(de)
|
1999-07-19 |
2001-01-25 |
Medigene Ag |
Strukturprotein in Adeno-assoziiertem Virus mit veränderten chromatographischen Eigenschaften, seine Herstellung und Verwendung
|
|
US6429001B1
(en)
|
2000-01-26 |
2002-08-06 |
Chiron Corporation |
Recombinant AAV packaging systems
|
|
US7465583B2
(en)
|
2000-06-01 |
2008-12-16 |
The University Of North Carolina At Chapel Hill |
Duplexed parvovirus vectors
|
|
US6410271B1
(en)
|
2000-06-23 |
2002-06-25 |
Genetastix Corporation |
Generation of highly diverse library of expression vectors via homologous recombination in yeast
|
|
US7749492B2
(en)
*
|
2001-01-05 |
2010-07-06 |
Nationwide Children's Hospital, Inc. |
AAV vectors and methods
|
|
US20070172460A1
(en)
|
2003-03-19 |
2007-07-26 |
Jurgen Kleinschmidt |
Random peptide library displayed on aav vectors
|
|
WO2005017101A2
(en)
|
2003-05-19 |
2005-02-24 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES, NATIONAL INSTITUTES OF HEALTH |
Avian adenoassociated virus (aaav) and uses thereof
|
|
US9233131B2
(en)
|
2003-06-30 |
2016-01-12 |
The Regents Of The University Of California |
Mutant adeno-associated virus virions and methods of use thereof
|
|
EP1668143B1
(en)
|
2003-09-30 |
2013-03-20 |
The Trustees of The University of Pennsylvania |
Adeno-associated virus (aav) clades, sequences, vectors containing same, and uses therefor
|
|
WO2006099615A2
(en)
|
2005-03-16 |
2006-09-21 |
The Johns Hopkins University |
Adenoviral fiber exchange shuttle system
|
|
US20090093403A1
(en)
|
2007-03-01 |
2009-04-09 |
Feng Zhang |
Systems, methods and compositions for optical stimulation of target cells
|
|
US7588772B2
(en)
*
|
2006-03-30 |
2009-09-15 |
Board Of Trustees Of The Leland Stamford Junior University |
AAV capsid library and AAV capsid proteins
|
|
WO2007148971A2
(en)
|
2006-06-21 |
2007-12-27 |
Amsterdam Molecular Therapeutics B.V. |
Vectors with modified initiation codon for the translation of aav-rep78 useful for production of aav in insect cells
|
|
WO2008103993A2
(en)
|
2007-02-23 |
2008-08-28 |
University Of Florida Research Foundation, Inc. |
Compositions and methods for treating glycogen storage diseases
|
|
CA2693712C
(en)
|
2007-07-14 |
2018-05-29 |
The University Of Iowa Research Foundation |
Methods and compositions for treating brain diseases
|
|
US9018138B2
(en)
|
2007-08-16 |
2015-04-28 |
The Johns Hopkins University |
Compositions and methods for generating and screening adenoviral libraries
|
|
WO2009108274A2
(en)
|
2008-02-26 |
2009-09-03 |
The University Of North Carolina At Chapel Hill |
Methods and compositions for adeno-associated virus (aav) with hi loop mutations
|
|
ES2701349T3
(es)
|
2008-04-23 |
2019-02-21 |
Univ Leland Stanford Junior |
Sistemas, métodos y composiciones para la estimulación óptica de células diana
|
|
US20110223635A1
(en)
|
2008-08-11 |
2011-09-15 |
Karl Deisseroth |
Method and Composition for Controlling Gene Expression
|
|
EP3399024A1
(en)
|
2010-03-17 |
2018-11-07 |
The Board of Trustees of The Leland Stanford Junior University |
Light-sensitive ion-passing molecules
|
|
DK2561073T3
(en)
|
2010-04-23 |
2016-12-12 |
Univ Massachusetts |
Aav vectors targeted to central nervous system and methods of use thereof
|
|
WO2012103343A1
(en)
|
2011-01-28 |
2012-08-02 |
The Board Of Trustees Of The Leland Stanford Junior University |
Functional targeted brain endoskeletonization
|
|
DK3693025T3
(da)
|
2011-04-22 |
2022-01-10 |
Univ California |
Adenoassocierede virus-virioner med variant capsid og fremgangsmåder til anvendelse heraf
|
|
EP3795581A3
(en)
|
2011-08-24 |
2021-06-09 |
The Board of Trustees of the Leland Stanford Junior University |
New avv capsid proteins for nucleic acid transfer
|
|
CA2859364C
(en)
|
2011-12-16 |
2019-05-07 |
The Board Of Trustees Of The Leland Stanford Junior University |
Opsin polypeptides and methods of use thereof
|
|
ES2628006T3
(es)
|
2012-02-21 |
2017-08-01 |
Circuit Therapeutics, Inc. |
Composiciones para el tratamiento de trastornos neurogénicos del suelo pélvico
|
|
PL2900686T3
(pl)
|
2012-09-28 |
2021-01-25 |
The University Of North Carolina At Chapel Hill |
Wektory aav ukierunkowane na oligodendrocyty
|
|
JP2016523835A
(ja)
|
2013-05-15 |
2016-08-12 |
リージェンツ オブ ザ ユニバーシティ オブ ミネソタ |
中枢神経系へのアデノ随伴ウイルスを介した遺伝子導入
|
|
EP3564379A1
(en)
*
|
2013-09-13 |
2019-11-06 |
California Institute of Technology |
Selective recovery
|
|
CN111514314A
(zh)
|
2013-09-19 |
2020-08-11 |
扬森疫苗与预防公司 |
改进的腺病毒配制品
|
|
US10794802B2
(en)
|
2013-09-20 |
2020-10-06 |
California Institute Of Technology |
Whole-body tissue stabilization and selective extractions via tissue-hydrogel hybrids for high resolution intact circuit mapping and phenotyping
|
|
US9778154B2
(en)
|
2013-09-20 |
2017-10-03 |
California Institute Of Technology |
Methods for phenotyping of intact whole tissues
|
|
WO2015127128A2
(en)
|
2014-02-19 |
2015-08-27 |
University Of Massachusetts |
Recombinant aavs having useful transcytosis properties
|
|
US10746742B2
(en)
|
2014-04-25 |
2020-08-18 |
Oregon Health & Science University |
Methods of viral neutralizing antibody epitope mapping
|
|
LT3137497T
(lt)
|
2014-05-02 |
2021-07-26 |
Genzyme Corporation |
Aav vektoriai, skirti tinklainės ir cns genų terapijai
|
|
WO2016065001A1
(en)
|
2014-10-21 |
2016-04-28 |
University Of Massachusetts |
Recombinant aav variants and uses thereof
|
|
AU2015349759B2
(en)
|
2014-11-21 |
2022-01-06 |
The University Of North Carolina At Chapel Hill |
Aav vectors targeted to the central nervous system
|
|
JP6836999B2
(ja)
|
2015-03-24 |
2021-03-03 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ |
アデノ随伴ウイルス変異体及びその使用方法
|
|
IL314171A
(en)
*
|
2015-09-28 |
2024-09-01 |
Univ Florida |
Methods and compositions for antibody-evading virus vectors
|
|
US20180230489A1
(en)
|
2015-10-28 |
2018-08-16 |
Voyager Therapeutics, Inc. |
Regulatable expression using adeno-associated virus (aav)
|
|
AU2016343979A1
(en)
|
2015-10-29 |
2018-05-10 |
Voyager Therapeutics, Inc. |
Delivery of central nervous system targeting polynucleotides
|
|
AU2016366549B2
(en)
*
|
2015-12-11 |
2022-11-10 |
California Institute Of Technology |
Targeting peptides for directing adeno-associated viruses (AAVs)
|
|
HRP20231451T1
(hr)
|
2016-02-05 |
2024-03-01 |
Emory University |
Ubrizgavanje jednolančanog ili samo-komplementarnog adeno-povezanog virusa 9 u cerebrospinalnu tekućinu
|
|
CA3014637A1
(en)
|
2016-02-16 |
2017-08-24 |
Mark A. Kay |
Novel recombinant adeno-associated virus capsids resistant to pre-existing human neutralizing antibodies
|
|
WO2017192750A1
(en)
|
2016-05-04 |
2017-11-09 |
Oregon Health & Science University |
Recombinant adeno-associated viral vectors
|
|
WO2017197355A2
(en)
|
2016-05-13 |
2017-11-16 |
4D Molecular Therapeutics Inc. |
Adeno-associated virus variant capsids and methods of use thereof
|
|
MA44546B1
(fr)
|
2016-06-15 |
2021-03-31 |
Univ California |
Virus adéno-associés variants et procédés d'utilisation
|
|
CN109640949B
(zh)
|
2016-07-29 |
2022-11-25 |
加利福尼亚大学董事会 |
具有变异衣壳的腺相关病毒病毒体和其使用方法
|
|
US9927975B2
(en)
|
2016-08-03 |
2018-03-27 |
Micron Technology, Inc. |
Hybrid memory drives, computer system, and related method for operating a multi-mode hybrid drive
|
|
WO2018045347A1
(en)
|
2016-09-02 |
2018-03-08 |
Spark Therapeutics, Inc. |
Methods and vectors for treating cns disorders
|
|
KR20190075964A
(ko)
|
2016-10-13 |
2019-07-01 |
유니버시티 오브 매사추세츠 |
Aav 캡시드 설계
|
|
US20190269797A1
(en)
|
2016-11-04 |
2019-09-05 |
The Children's Hospital Of Philadelphia |
Gene transfer compositions, methods and uses for treating neurodegenerative diseases
|
|
US20230048025A1
(en)
|
2016-12-22 |
2023-02-16 |
Oregon Health & Science University |
Adeno associated viral vectors
|
|
EP3583220A4
(en)
|
2017-02-15 |
2021-07-07 |
The University of North Carolina at Chapel Hill |
PROCEDURES AND COMPOSITIONS FOR GENERAL TRANSFER IN THE VASCULAR SYSTEM
|
|
JP2020510424A
(ja)
*
|
2017-02-28 |
2020-04-09 |
アドヴェラム バイオテクノロジーズ， インコーポレイテッド |
改変ａａｖカプシドおよびその使用
|
|
US10550405B2
(en)
*
|
2017-03-15 |
2020-02-04 |
The University Of North Carolina At Chapel Hill |
Rational polyploid adeno-associated virus vectors and methods of making and using the same
|
|
CN117821509A
(zh)
|
2017-04-03 |
2024-04-05 |
编码治疗公司 |
组织选择性转基因表达
|
|
EP3618839A4
(en)
*
|
2017-05-05 |
2021-06-09 |
Voyager Therapeutics, Inc. |
COMPOSITIONS AND METHODS OF TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS (ALS)
|
|
WO2018222503A1
(en)
|
2017-05-31 |
2018-12-06 |
The Regents Of The University Of California |
Adeno-associated virus with variant capsid and methods of use thereof
|
|
KR20250023600A
(ko)
|
2017-06-30 |
2025-02-18 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
변이체 캡시드를 보유한 아데노-부속 바이러스 비리온 및 이의 사용 방법
|
|
US11512327B2
(en)
|
2017-08-03 |
2022-11-29 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of AAV
|
|
MX2020001997A
(es)
|
2017-08-28 |
2020-07-20 |
Univ California |
Variantes de capside de virus adenoasociado y metodos de uso de estas.
|
|
DK3684423T5
(da)
|
2017-09-20 |
2024-08-26 |
4D Molecular Therapeutics Inc |
Adeno-associerede virusvariantcapsider og fremgangsmåder til anvendelse deraf
|
|
US11766489B2
(en)
|
2017-11-27 |
2023-09-26 |
4D Molecular Therapeutics, Inc. |
Adeno-associated virus variant capsids and use for inhibiting angiogenesis
|
|
EP3774853A1
(en)
|
2018-03-30 |
2021-02-17 |
The Board of Trustees of the Leland Stanford Junior University |
Novel recombinant adeno-associated virus capsids with enhanced human pancreatic tropism
|
|
CA3097375A1
(en)
|
2018-04-27 |
2019-10-31 |
Universitat Heidelberg |
Modified aav capsid polypeptides for treatment of muscular diseases
|
|
WO2019222329A1
(en)
|
2018-05-15 |
2019-11-21 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
|
US20210207167A1
(en)
|
2018-05-16 |
2021-07-08 |
Voyager Therapeutics, Inc. |
Aav serotypes for brain specific payload delivery
|
|
WO2019222444A2
(en)
|
2018-05-16 |
2019-11-21 |
Voyager Therapeutics, Inc. |
Directed evolution
|
|
EP3830107A2
(en)
|
2018-08-03 |
2021-06-09 |
Voyager Therapeutics, Inc. |
Aav variants with enhanced tropism
|
|
US11858969B2
(en)
|
2018-09-18 |
2024-01-02 |
California Institute Of Technology |
Engineered light-sensitive proteins
|
|
US11149256B2
(en)
|
2018-09-26 |
2021-10-19 |
California Institute Of Technology |
Adeno-associated virus compositions for targeted gene therapy
|
|
US20210371470A1
(en)
|
2018-10-12 |
2021-12-02 |
Voyager Therapeutics, Inc. |
Compositions and methods for delivery of aav
|
|
JP7659271B2
(ja)
|
2019-03-28 |
2025-04-09 |
ザ ジェネラル ホスピタル コーポレイション |
導入遺伝子発現のための操作されたアデノ随伴（ａａｖ）ベクター
|
|
TW202102526A
(zh)
|
2019-04-04 |
2021-01-16 |
美商銳進科斯生物股份有限公司 |
重組腺相關病毒及其用途
|
|
SG11202111249YA
(en)
|
2019-04-11 |
2021-11-29 |
California Inst Of Techn |
Virus compositions with enhanced specificity in the brain
|
|
EA202192801A1
(ru)
|
2019-04-12 |
2022-02-24 |
Инкоудид Терапьютикс, Инк. |
Композиции и способы введения лекарственных средств
|
|
CN114269926A
(zh)
|
2019-04-26 |
2022-04-01 |
美商圣加莫治疗股份有限公司 |
Aav工程化
|
|
SG11202113048SA
(en)
|
2019-05-29 |
2021-12-30 |
Encoded Therapeutics Inc |
Compositions and methods for selective gene regulation
|