JP2022164822A5 - - Google Patents

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Publication number
JP2022164822A5
JP2022164822A5 JP2022137773A JP2022137773A JP2022164822A5 JP 2022164822 A5 JP2022164822 A5 JP 2022164822A5 JP 2022137773 A JP2022137773 A JP 2022137773A JP 2022137773 A JP2022137773 A JP 2022137773A JP 2022164822 A5 JP2022164822 A5 JP 2022164822A5
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JP
Japan
Prior art keywords
zfn
nuclease
seq
composition
cell
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JP2022137773A
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English (en)
Japanese (ja)
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JP2022164822A (ja
JP7482176B2 (ja
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Priority claimed from JP2019568660A external-priority patent/JP7419073B2/ja
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Publication of JP2022164822A publication Critical patent/JP2022164822A/ja
Publication of JP2022164822A5 publication Critical patent/JP2022164822A5/ja
Priority to JP2024017157A priority Critical patent/JP2024036610A/ja
Application granted granted Critical
Publication of JP7482176B2 publication Critical patent/JP7482176B2/ja
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JP2022137773A 2017-06-16 2022-08-31 T細胞および/またはhla受容体の標的化破壊 Active JP7482176B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024017157A JP2024036610A (ja) 2017-06-16 2024-02-07 T細胞および/またはhla受容体の標的化破壊

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201762521132P 2017-06-16 2017-06-16
US62/521,132 2017-06-16
US201762542052P 2017-08-07 2017-08-07
US62/542,052 2017-08-07
US201762573956P 2017-10-18 2017-10-18
US62/573,956 2017-10-18
JP2019568660A JP7419073B2 (ja) 2017-06-16 2018-06-15 T細胞および/またはhla受容体の標的化破壊
PCT/US2018/037844 WO2018232296A1 (en) 2017-06-16 2018-06-15 Targeted disruption of t cell and/or hla receptors

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019568660A Division JP7419073B2 (ja) 2017-06-16 2018-06-15 T細胞および/またはhla受容体の標的化破壊

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024017157A Division JP2024036610A (ja) 2017-06-16 2024-02-07 T細胞および/またはhla受容体の標的化破壊

Publications (3)

Publication Number Publication Date
JP2022164822A JP2022164822A (ja) 2022-10-27
JP2022164822A5 true JP2022164822A5 (enExample) 2023-09-19
JP7482176B2 JP7482176B2 (ja) 2024-05-13

Family

ID=64656803

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2019568660A Active JP7419073B2 (ja) 2017-06-16 2018-06-15 T細胞および/またはhla受容体の標的化破壊
JP2022137773A Active JP7482176B2 (ja) 2017-06-16 2022-08-31 T細胞および/またはhla受容体の標的化破壊
JP2024017157A Pending JP2024036610A (ja) 2017-06-16 2024-02-07 T細胞および/またはhla受容体の標的化破壊

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2019568660A Active JP7419073B2 (ja) 2017-06-16 2018-06-15 T細胞および/またはhla受容体の標的化破壊

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024017157A Pending JP2024036610A (ja) 2017-06-16 2024-02-07 T細胞および/またはhla受容体の標的化破壊

Country Status (11)

Country Link
US (1) US20230295563A1 (enExample)
EP (1) EP3638783A4 (enExample)
JP (3) JP7419073B2 (enExample)
KR (1) KR102708624B1 (enExample)
CN (1) CN110997913B (enExample)
AU (1) AU2018283310B2 (enExample)
BR (1) BR112019026622A2 (enExample)
CA (1) CA3066641A1 (enExample)
IL (1) IL271298A (enExample)
SG (1) SG11201911729SA (enExample)
WO (1) WO2018232296A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3051113A1 (en) * 2017-01-26 2018-08-02 Sangamo Therapeutics, Inc. B-cell engineering
JP2022500052A (ja) * 2018-09-18 2022-01-04 サンガモ セラピューティクス, インコーポレイテッド プログラム細胞死1(pd1)特異的ヌクレアーゼ
WO2022094154A1 (en) 2020-10-28 2022-05-05 Sangamo Therapeutics, Inc. Generation of cd4+ effector and regulatory t cells from human pluripotent stem cells
CN113846070B (zh) * 2021-10-18 2023-05-16 翌圣生物科技(上海)股份有限公司 高活性的mTET2酶突变体、其编码DNA及其应用
CN118813625B (zh) * 2024-06-17 2025-08-26 天海元祺生物科技(天津)有限公司 高度靶向人类HLA-A基因的sgRNA及应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1618218A2 (en) * 2003-04-29 2006-01-25 Wyeth Methods for prognosis and treatment of solid tumors
US8791324B2 (en) * 2008-04-21 2014-07-29 Danziger Innovations Ltd. Plant viral expression vectors and use of same for generating genotypic variations in plant genomes
JP5955871B2 (ja) * 2011-03-17 2016-07-20 ミルテニイ バイオテック ゲゼルシャフト ミット ベシュレンクテル ハフツング Tcrアルファ/ベータを枯渇させた細胞調製物
WO2012127464A2 (en) * 2011-03-23 2012-09-27 Gavish-Galilee Bio Applications Ltd Constitutively activated t cells for use in adoptive cell therapy
EP3591045B1 (en) * 2013-08-28 2024-07-17 Sangamo Therapeutics, Inc. Compositions for linking dna-binding domains and cleavage domains
KR102228828B1 (ko) * 2014-03-11 2021-03-16 셀렉티스 동종이형 이식에 양립성인 t-세포들을 만들어내는 방법
CN107405411A (zh) * 2014-05-01 2017-11-28 华盛顿大学 使用腺病毒载体的体内基因改造
AU2016291778B2 (en) * 2015-07-13 2021-05-06 Sangamo Therapeutics, Inc. Delivery methods and compositions for nuclease-mediated genome engineering
KR20180088911A (ko) * 2015-12-18 2018-08-07 상가모 테라퓨틱스, 인코포레이티드 Mhc 세포 수용체의 표적화된 붕괴
WO2017106528A2 (en) * 2015-12-18 2017-06-22 Sangamo Biosciences, Inc. Targeted disruption of the t cell receptor
IL272302B2 (en) * 2017-08-08 2025-01-01 Sangamo Therapeutics Inc Targeting T cells with genetic modifications mediated by a chimeric antigen receptor
RU2020129448A (ru) * 2018-02-08 2022-03-09 Сангамо Терапьютикс, Инк. Сконструированные специфические для мишени нуклеазы

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