KR102708624B1 - T 세포 및/또는 hla 수용체의 표적화된 파괴 - Google Patents

T 세포 및/또는 hla 수용체의 표적화된 파괴 Download PDF

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KR102708624B1
KR102708624B1 KR1020207000964A KR20207000964A KR102708624B1 KR 102708624 B1 KR102708624 B1 KR 102708624B1 KR 1020207000964 A KR1020207000964 A KR 1020207000964A KR 20207000964 A KR20207000964 A KR 20207000964A KR 102708624 B1 KR102708624 B1 KR 102708624B1
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gene
cells
cell
dna
seq
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KR20200018623A (ko
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앤서니 콘웨이
수미티 제인
개리 케이. 리
데이빗 파숀
에드워드 제이. 리바
레이 장
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상가모 테라퓨틱스, 인코포레이티드
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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KR1020207000964A 2017-06-16 2018-06-15 T 세포 및/또는 hla 수용체의 표적화된 파괴 Active KR102708624B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762521132P 2017-06-16 2017-06-16
US62/521,132 2017-06-16
US201762542052P 2017-08-07 2017-08-07
US62/542,052 2017-08-07
US201762573956P 2017-10-18 2017-10-18
US62/573,956 2017-10-18
PCT/US2018/037844 WO2018232296A1 (en) 2017-06-16 2018-06-15 Targeted disruption of t cell and/or hla receptors

Publications (2)

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KR20200018623A KR20200018623A (ko) 2020-02-19
KR102708624B1 true KR102708624B1 (ko) 2024-09-20

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US (1) US20230295563A1 (enExample)
EP (1) EP3638783A4 (enExample)
JP (3) JP7419073B2 (enExample)
KR (1) KR102708624B1 (enExample)
CN (1) CN110997913B (enExample)
AU (1) AU2018283310B2 (enExample)
BR (1) BR112019026622A2 (enExample)
CA (1) CA3066641A1 (enExample)
IL (1) IL271298A (enExample)
SG (1) SG11201911729SA (enExample)
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EP3573464A4 (en) * 2017-01-26 2020-12-30 Sangamo Therapeutics, Inc. B CELL ENGINEERING
WO2020061161A1 (en) * 2018-09-18 2020-03-26 Sangamo Therapeutics, Inc. Programmed cell death 1 (pd1) specific nucleases
CN116323921A (zh) 2020-10-28 2023-06-23 桑格摩生物治疗股份有限公司 从人多能干细胞生成cd4+效应t细胞和调节性t细胞
CN113846070B (zh) * 2021-10-18 2023-05-16 翌圣生物科技(上海)股份有限公司 高活性的mTET2酶突变体、其编码DNA及其应用
CN118813625B (zh) * 2024-06-17 2025-08-26 天海元祺生物科技(天津)有限公司 高度靶向人类HLA-A基因的sgRNA及应用

Citations (2)

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JP2016528915A (ja) * 2013-08-28 2016-09-23 サンガモ バイオサイエンシーズ， インコーポレイテッド Ｄｎａ結合ドメインと切断ドメインとを連結するための組成物
US20190241877A1 (en) * 2018-02-08 2019-08-08 Sangamo Therapeutics, Inc. Engineered target specific nucleases

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AU2004235395A1 (en) * 2003-04-29 2004-11-11 Wyeth Methods for prognosis and treatment of solid tumors
CA2721372A1 (en) * 2008-04-21 2009-10-29 Danziger Innovations Ltd. Plant viral expression vectors and use of same for generating genotypic variations in plant genomes
EP2686417B1 (de) * 2011-03-17 2016-06-08 Miltenyi Biotec GmbH Tcralpha/beta-depletierte zellpräparationen
WO2012127464A2 (en) * 2011-03-23 2012-09-27 Gavish-Galilee Bio Applications Ltd Constitutively activated t cells for use in adoptive cell therapy
ES2782125T3 (es) * 2014-03-11 2020-09-10 Cellectis Método para generar linfocitos T compatibles para trasplante alogénico
BR112016025519A2 (pt) * 2014-05-01 2018-01-16 Univ Washington engenharia genética in vivo com vetores de adenovírus
WO2017011519A1 (en) * 2015-07-13 2017-01-19 Sangamo Biosciences, Inc. Delivery methods and compositions for nuclease-mediated genome engineering
CN108699132B (zh) * 2015-12-18 2023-08-11 桑格摩生物治疗股份有限公司 Mhc细胞受体的靶向破坏
ES2983043T3 (es) * 2015-12-18 2024-10-21 Sangamo Therapeutics Inc Alteración dirigida del receptor de células T
MX2020001594A (es) * 2017-08-08 2020-12-09 Sangamo Therapeutics Inc Direccionamiento celular mediado por receptor de antigeno quimerico.

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016528915A (ja) * 2013-08-28 2016-09-23 サンガモ バイオサイエンシーズ， インコーポレイテッド Ｄｎａ結合ドメインと切断ドメインとを連結するための組成物
US20190241877A1 (en) * 2018-02-08 2019-08-08 Sangamo Therapeutics, Inc. Engineered target specific nucleases

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EP3638783A1 (en) 2020-04-22
CA3066641A1 (en) 2018-12-20
SG11201911729SA (en) 2020-01-30
EP3638783A4 (en) 2021-03-10
IL271298A (en) 2020-01-30
CN110997913A (zh) 2020-04-10
AU2018283310A1 (en) 2020-01-02
KR20200018623A (ko) 2020-02-19
JP2022164822A (ja) 2022-10-27
CN110997913B (zh) 2024-05-28
JP7419073B2 (ja) 2024-01-22
WO2018232296A1 (en) 2018-12-20
JP2024036610A (ja) 2024-03-15
US20230295563A1 (en) 2023-09-21
JP2020524994A (ja) 2020-08-27
BR112019026622A2 (pt) 2020-06-30
JP7482176B2 (ja) 2024-05-13
AU2018283310B2 (en) 2025-02-13

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