JP2022122913A5 - - Google Patents
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- Publication number
- JP2022122913A5 JP2022122913A5 JP2022084419A JP2022084419A JP2022122913A5 JP 2022122913 A5 JP2022122913 A5 JP 2022122913A5 JP 2022084419 A JP2022084419 A JP 2022084419A JP 2022084419 A JP2022084419 A JP 2022084419A JP 2022122913 A5 JP2022122913 A5 JP 2022122913A5
- Authority
- JP
- Japan
- Prior art keywords
- sequence
- amino acid
- tcr
- acid residues
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1606156.6 | 2016-04-08 | ||
| GB201606156 | 2016-04-08 | ||
| JP2018552775A JP7204484B2 (ja) | 2016-04-08 | 2017-04-10 | Ｔ細胞受容体 |
| PCT/EP2017/058578 WO2017174823A1 (en) | 2016-04-08 | 2017-04-10 | T cell receptors |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018552775A Division JP7204484B2 (ja) | 2016-04-08 | 2017-04-10 | Ｔ細胞受容体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022122913A JP2022122913A (ja) | 2022-08-23 |
| JP2022122913A5 true JP2022122913A5 (https=) | 2023-04-07 |
| JP7572399B2 JP7572399B2 (ja) | 2024-10-23 |
Family
ID=58536983
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018552775A Active JP7204484B2 (ja) | 2016-04-08 | 2017-04-10 | Ｔ細胞受容体 |
| JP2022084419A Active JP7572399B2 (ja) | 2016-04-08 | 2022-05-24 | Ｔ細胞受容体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018552775A Active JP7204484B2 (ja) | 2016-04-08 | 2017-04-10 | Ｔ細胞受容体 |
Country Status (15)
| Country | Link |
|---|---|
| US (3) | US20190144521A1 (https=) |
| EP (2) | EP3925972A1 (https=) |
| JP (2) | JP7204484B2 (https=) |
| KR (1) | KR20190065189A (https=) |
| CN (2) | CN116239669A (https=) |
| AU (2) | AU2017248121B2 (https=) |
| BR (1) | BR112018070637A2 (https=) |
| CA (1) | CA3020555A1 (https=) |
| ES (1) | ES2788188T5 (https=) |
| IL (1) | IL262124A (https=) |
| MX (1) | MX389173B (https=) |
| RU (1) | RU2018138837A (https=) |
| SG (1) | SG11201808750PA (https=) |
| WO (1) | WO2017174823A1 (https=) |
| ZA (1) | ZA201806862B (https=) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201501017D0 (en) | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
| MA49156A (fr) | 2014-12-23 | 2020-03-25 | Immatics Biotechnologies Gmbh | Nouveaux peptides et combinaison de peptides à utiliser dans l'immunothérapie contre le carcinome hépatocellulaire (hcc) et d'autres cancers |
| DK3440106T3 (da) | 2016-04-08 | 2021-10-04 | Adaptimmune Ltd | T-cellereceptorer |
| KR20190059874A (ko) * | 2016-04-08 | 2019-05-31 | 어댑티뮨 리미티드 | T 세포 수용체 |
| BR112018070637A2 (pt) | 2016-04-08 | 2019-02-05 | Adaptimmune Ltd | receptores de células t |
| WO2019069125A1 (en) | 2017-10-06 | 2019-04-11 | Oslo Universitetssykehus Hf | CHIMERIC ANTIGEN RECEPTORS |
| EP3747456A4 (en) * | 2018-01-31 | 2021-12-01 | Tohoku University | PROCESS FOR REGULATING THE EXPRESSION OF THE SPECIFIC MHC OF AN ANTIGEN |
| WO2019204683A1 (en) * | 2018-04-19 | 2019-10-24 | Board Of Regents, The University Of Texas System | T cell receptors with mage-b2 specificity and uses thereof |
| GB201819540D0 (en) * | 2018-11-30 | 2019-01-16 | Adaptimmune Ltd | T cell modification |
| CN110172091B (zh) * | 2019-04-28 | 2020-04-03 | 天津亨佳生物科技发展有限公司 | 一种针对egfr l858r基因突变的特异性t细胞受体及其应用 |
| PH12021553152A1 (en) * | 2019-06-18 | 2022-08-15 | Regeneron Pharma | Mage-a4 t cell receptors and methods of use thereof |
| WO2020263830A1 (en) | 2019-06-25 | 2020-12-30 | Gilead Sciences, Inc. | Flt3l-fc fusion proteins and methods of use |
| US12480958B2 (en) | 2019-08-13 | 2025-11-25 | Immatics Biotechnologies Gmbh | Method for the characterization of peptide:MHC binding polypeptides |
| AU2020327671A1 (en) | 2019-08-13 | 2022-03-03 | King's College London | Immunoresponsive cells armoured with spatiotemporally restricted activity of cytokines of the IL-1 superfamily |
| TWI890283B (zh) | 2020-02-14 | 2025-07-11 | 美商基利科學股份有限公司 | 結合ccr8之抗體及融合蛋白及其用途 |
| CA3183756A1 (en) | 2020-05-19 | 2021-11-25 | Amgen Inc. | Mageb2 binding constructs |
| CN111647069B (zh) * | 2020-06-17 | 2022-06-21 | 深圳豪石生物科技有限公司 | 一种改进的tcr及其应用 |
| TW202406932A (zh) | 2020-10-22 | 2024-02-16 | 美商基利科學股份有限公司 | 介白素2-Fc融合蛋白及使用方法 |
| AU2021410689A1 (en) * | 2020-12-22 | 2023-07-06 | Amgen Inc. | Mage-b2-specific t-cell receptors |
| US12435444B2 (en) | 2021-03-09 | 2025-10-07 | Cdr-Life Ag | Rabbit-derived antigen binding protein nucleic acid libraries and methods of making the same |
| MX2023010541A (es) | 2021-03-09 | 2023-11-24 | Cdr Life Ag | Proteinas de union al antigeno del peptido del mhc mage-a4. |
| WO2022245671A1 (en) | 2021-05-18 | 2022-11-24 | Gilead Sciences, Inc. | Methods of using flt3l-fc fusion proteins |
| AU2022375782B2 (en) | 2021-10-28 | 2026-02-26 | Gilead Sciences, Inc. | Pyridizin-3(2h)-one derivatives |
| JP7787991B2 (ja) | 2021-10-29 | 2025-12-17 | ギリアード サイエンシーズ， インコーポレイテッド | Ｃｄ７３化合物 |
| KR20240123836A (ko) | 2021-12-22 | 2024-08-14 | 길리애드 사이언시즈, 인코포레이티드 | 이카로스 아연 핑거 패밀리 분해제 및 이의 용도 |
| US12122764B2 (en) | 2021-12-22 | 2024-10-22 | Gilead Sciences, Inc. | IKAROS zinc finger family degraders and uses thereof |
| TW202340168A (zh) | 2022-01-28 | 2023-10-16 | 美商基利科學股份有限公司 | Ｐａｒｐ７抑制劑 |
| WO2023178181A1 (en) | 2022-03-17 | 2023-09-21 | Gilead Sciences, Inc. | Ikaros zinc finger family degraders and uses thereof |
| CN116836261A (zh) * | 2022-03-24 | 2023-10-03 | 香雪生命科学技术（广东）有限公司 | 一种识别mage-a4抗原的高亲和力tcr及其序列和应用 |
| CR20240451A (es) | 2022-04-21 | 2024-12-04 | Gilead Sciences Inc | Compuestos de modulación de kras g12d |
| CN117106060A (zh) * | 2022-05-17 | 2023-11-24 | 香雪生命科学技术（广东）有限公司 | 一种识别mage的高亲和力t细胞受体及其应用 |
| KR20250028371A (ko) | 2022-07-01 | 2025-02-28 | 길리애드 사이언시즈, 인코포레이티드 | Cd73 화합물 |
| CA3264474A1 (en) | 2022-09-14 | 2024-03-21 | Cdr-Life Ag | MAGE-A4 DOUBLE T LYMPHOCYTE ENGAGEMENT |
| AU2023409398A1 (en) | 2022-12-22 | 2025-06-05 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| AU2024252725A1 (en) | 2023-04-11 | 2025-11-06 | Gilead Sciences, Inc. | Kras modulating compounds |
| CR20250446A (es) | 2023-04-21 | 2025-12-02 | Gilead Sciences Inc | Inhibidores de prmt5 y usos de los mismos |
| AU2024306338A1 (en) | 2023-06-30 | 2026-01-08 | Gilead Sciences, Inc. | Kras modulating compounds |
| CN121620513A (zh) | 2023-07-26 | 2026-03-06 | 吉利德科学公司 | Parp7抑制剂 |
| KR20260046403A (ko) | 2023-07-26 | 2026-04-07 | 길리애드 사이언시즈, 인코포레이티드 | Parp7 저해제 |
| WO2025021979A1 (en) * | 2023-07-27 | 2025-01-30 | Immatics Biotechnologies Gmbh | Novel t cell receptors targeting melanoma-associated antigen (mage) b2 and immune therapy using the same |
| CN121358777A (zh) * | 2023-07-27 | 2026-01-16 | 伊玛提克斯生物技术有限公司 | 抗mageb2的抗原结合蛋白 |
| US20250101042A1 (en) | 2023-09-08 | 2025-03-27 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| US20250109147A1 (en) | 2023-09-08 | 2025-04-03 | Gilead Sciences, Inc. | Kras g12d modulating compounds |
| US20250154172A1 (en) | 2023-11-03 | 2025-05-15 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| WO2025137640A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
| WO2025245003A1 (en) | 2024-05-21 | 2025-11-27 | Gilead Sciences, Inc. | Prmt5 inhibitors and uses thereof |
| US20260098049A1 (en) | 2024-08-12 | 2026-04-09 | Gilead Sciences, Inc. | Kras modulating compounds |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6596536B1 (en) * | 1991-02-08 | 2003-07-22 | Aventis Pharma S.A. | Nucleotide sequences coding for variable regions of the alpha chains of human T lymphocyte receptors, corresponding peptide segments and the diagnostic and therapeutic uses |
| US6407063B1 (en) | 1998-10-02 | 2002-06-18 | Ludwig Institute For Cancer Research | Tumor antigens and CTL clones isolated by a novel procedure |
| WO2000020445A2 (en) | 1998-10-02 | 2000-04-13 | Ludwig Institute For Cancer Research | Tumor antigens and ctl clones isolated by a novel procedure |
| US20050053918A1 (en) | 2001-05-16 | 2005-03-10 | Technion Research & Development Foundation Ltd. | Method of identifying peptides capable of binding to MHC molecules, peptides identified thereby and their uses |
| US6867283B2 (en) * | 2001-05-16 | 2005-03-15 | Technion Research & Development Foundation Ltd. | Peptides capable of binding to MHC molecules, cells presenting such peptides, and pharmaceutical compositions comprising such peptides and/or cells |
| IL160359A0 (en) | 2001-08-31 | 2004-07-25 | Avidex Ltd | Soluble t cell receptor |
| GB0304068D0 (en) * | 2003-02-22 | 2003-03-26 | Avidex Ltd | Substances |
| US20120009162A1 (en) * | 2009-04-03 | 2012-01-12 | Masaki Yasukawa | T cell receptor and nucleic acid encoding the receptor |
| ES2533228T3 (es) | 2009-06-09 | 2015-04-08 | Vaxon Biotech | Identificación, optimización y uso de epítopos compartidos de HLA-B*0702 para inmunoterapia |
| HRP20171164T1 (hr) | 2010-09-20 | 2017-10-20 | Biontech Cell & Gene Therapies Gmbh | Antigen-specifični t stanični receptori i t stanični epitopi |
| SG11201400521PA (en) * | 2011-10-14 | 2014-08-28 | Teva Pharmaceuticals Australia Pty Ltd | ANTIBODIES TO CD1d |
| CA3051222C (en) * | 2013-06-10 | 2023-01-24 | Dana-Farber Cancer Institute, Inc. | Methods and compositions for reducing immunosupression by tumor cells |
| JP6255360B2 (ja) | 2015-03-04 | 2017-12-27 | ヴァクソン バイオテックＶａｘｏｎ Ｂｉｏｔｅｃｈ | 共有ｈｌａ−ｂ＊０７０２エピトープの同定、最適化および免疫療法のための使用 |
| KR20190059874A (ko) | 2016-04-08 | 2019-05-31 | 어댑티뮨 리미티드 | T 세포 수용체 |
| BR112018070637A2 (pt) | 2016-04-08 | 2019-02-05 | Adaptimmune Ltd | receptores de células t |
| SMT202200306T1 (it) | 2016-04-08 | 2022-09-14 | Immunocore Ltd | Recettori di cellule t |
| DK3440106T3 (da) | 2016-04-08 | 2021-10-04 | Adaptimmune Ltd | T-cellereceptorer |
-
2017
- 2017-04-10 BR BR112018070637A patent/BR112018070637A2/pt not_active Application Discontinuation
- 2017-04-10 CN CN202310214446.3A patent/CN116239669A/zh active Pending
- 2017-04-10 EP EP20020115.0A patent/EP3925972A1/en not_active Withdrawn
- 2017-04-10 WO PCT/EP2017/058578 patent/WO2017174823A1/en not_active Ceased
- 2017-04-10 SG SG11201808750PA patent/SG11201808750PA/en unknown
- 2017-04-10 CA CA3020555A patent/CA3020555A1/en active Pending
- 2017-04-10 KR KR1020187032157A patent/KR20190065189A/ko not_active Ceased
- 2017-04-10 ES ES17716871T patent/ES2788188T5/es active Active
- 2017-04-10 EP EP17716871.3A patent/EP3440104B2/en active Active
- 2017-04-10 JP JP2018552775A patent/JP7204484B2/ja active Active
- 2017-04-10 MX MX2018012268A patent/MX389173B/es unknown
- 2017-04-10 RU RU2018138837A patent/RU2018138837A/ru unknown
- 2017-04-10 CN CN201780031701.3A patent/CN109476724B/zh not_active Expired - Fee Related
- 2017-04-10 AU AU2017248121A patent/AU2017248121B2/en not_active Ceased
-
2018
- 2018-10-04 IL IL262124A patent/IL262124A/en unknown
- 2018-10-08 US US16/154,270 patent/US20190144521A1/en not_active Abandoned
- 2018-10-15 ZA ZA2018/06862A patent/ZA201806862B/en unknown
-
2021
- 2021-10-14 US US17/501,200 patent/US11753456B2/en active Active
-
2022
- 2022-05-24 JP JP2022084419A patent/JP7572399B2/ja active Active
- 2022-10-20 AU AU2022256182A patent/AU2022256182A1/en not_active Abandoned
-
2023
- 2023-08-01 US US18/363,672 patent/US12180261B2/en active Active
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