JP2023524788A5 - - Google Patents

Info

Publication number
JP2023524788A5
JP2023524788A5 JP2022567414A JP2022567414A JP2023524788A5 JP 2023524788 A5 JP2023524788 A5 JP 2023524788A5 JP 2022567414 A JP2022567414 A JP 2022567414A JP 2022567414 A JP2022567414 A JP 2022567414A JP 2023524788 A5 JP2023524788 A5 JP 2023524788A5
Authority
JP
Japan
Prior art keywords
seq
chain
specific binding
amino acid
binding molecule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2022567414A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023524788A (ja
JP7682927B2 (ja
Filing date
Publication date
Priority claimed from GBGB2006629.6A external-priority patent/GB202006629D0/en
Application filed filed Critical
Publication of JP2023524788A publication Critical patent/JP2023524788A/ja
Publication of JP2023524788A5 publication Critical patent/JP2023524788A5/ja
Application granted granted Critical
Publication of JP7682927B2 publication Critical patent/JP7682927B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2022567414A 2020-05-05 2021-05-04 特異的結合性分子 Active JP7682927B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB2006629.6A GB202006629D0 (en) 2020-05-05 2020-05-05 Specific binding molecules
GB2006629.6 2020-05-05
PCT/EP2021/061731 WO2021224261A1 (en) 2020-05-05 2021-05-04 Soluble tors and fusions to anti-cd3 recognising kras g12d for the treatment of cancer

Publications (3)

Publication Number Publication Date
JP2023524788A JP2023524788A (ja) 2023-06-13
JP2023524788A5 true JP2023524788A5 (https=) 2024-01-30
JP7682927B2 JP7682927B2 (ja) 2025-05-26

Family

ID=71080372

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022567414A Active JP7682927B2 (ja) 2020-05-05 2021-05-04 特異的結合性分子

Country Status (8)

Country Link
US (1) US20230348595A1 (https=)
EP (1) EP4146257A1 (https=)
JP (1) JP7682927B2 (https=)
CN (1) CN115867310A (https=)
AU (1) AU2021267361A1 (https=)
CA (1) CA3181362A1 (https=)
GB (1) GB202006629D0 (https=)
WO (1) WO2021224261A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201901305D0 (en) * 2019-01-30 2019-03-20 Immunocore Ltd Specific binding molecules
IL308258A (en) 2021-05-05 2024-01-01 Immatics Biotechnologies Gmbh Bma031 antigen binding polypeptides
CN115850444B (zh) * 2022-09-15 2025-01-28 重庆医科大学 Tcr或其抗原结合片段及其应用
CN118812698A (zh) * 2023-04-19 2024-10-22 香雪生命科学技术（广东）有限公司 一种识别kras突变的高亲和力t细胞受体及其应用
CN118852403A (zh) * 2023-04-26 2024-10-29 北京鼎成肽源生物技术有限公司 靶向kras突变的tcr分子和细胞及其应用
CN118852452A (zh) * 2023-04-28 2024-10-29 北京鼎成肽源生物技术有限公司 靶向kras g12突变的tcr分子和细胞及其应用
CN120157754A (zh) * 2023-12-14 2025-06-17 新景智源生物科技(苏州)有限公司 Kras_g12d突变抗原特异性tcr及其与cd8共表达重定向cd4 t细胞
WO2025189363A1 (zh) * 2024-03-12 2025-09-18 广州医科大学 一种t细胞受体(tcr)及其用途
CN120647748B (zh) * 2025-05-16 2026-03-06 浙江大学 一种活性提升的tcr及其用途

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039482A1 (en) 1997-03-07 1998-09-11 Sunol Molecular Corporation Fusion proteins comprising bacteriophage coat protein and a single-chain t cell receptor
ATE533784T1 (de) 1997-10-02 2011-12-15 Altor Bioscience Corp Lösliche, einzelkettige proteine des t- zellrezeptors
MXPA02005559A (es) 1999-12-06 2004-09-10 Univ Illinois Proteinas de tcr de alta afinidad y metodos.
EP1259601A2 (en) 2000-02-22 2002-11-27 Ahuva Nissim Chimeric and tcr phage display libraries, chimeric and tcr reagents and methods of use thereof
IL160359A0 (en) 2001-08-31 2004-07-25 Avidex Ltd Soluble t cell receptor
CA2501870C (en) 2002-10-09 2013-07-02 Avidex Limited Single chain recombinant t cell receptors
PT1558643E (pt) 2002-11-09 2009-08-24 Immunocore Ltd Apresentação de um receptor das células t
GB0908613D0 (en) 2009-05-20 2009-06-24 Immunocore Ltd T Cell Reseptors
GB0911566D0 (en) * 2009-07-03 2009-08-12 Immunocore Ltd T cell receptors
GB201223172D0 (en) 2012-12-21 2013-02-06 Immunocore Ltd Method
GB201314404D0 (en) * 2013-08-12 2013-09-25 Immunocore Ltd T Cell Receptors
GB201505305D0 (en) * 2015-03-27 2015-05-13 Immatics Biotechnologies Gmbh Novel Peptides and combination of peptides for use in immunotherapy against various tumors
US11827688B2 (en) 2016-06-02 2023-11-28 Immunocore Limited Dosing regimen for GP100-specific TCR—anti-CD3 SCFV fusion protein
LT3428194T (lt) 2017-07-14 2021-12-10 Immatics Biotechnologies Gmbh Pagerinta dvejopo savitumo polipeptido molekulė

Similar Documents

Publication Publication Date Title
JP2023524788A5 (https=)
JP2023522799A5 (https=)
JP2020530762A5 (https=)
RU2762255C2 (ru) Т-клеточные рецепторы
RU2742691C2 (ru) Cd3-связывающий домен
JP2021524267A5 (https=)
JP2019023184A5 (https=)
HRP20211744T1 (hr) Poboljšana molekula polipeptida dvostruke specifičnosti
IL308831A (en) T cell receptors
JP2022542543A5 (https=)
JP2021524268A5 (https=)
JP7682927B2 (ja) 特異的結合性分子
JP2021520831A5 (https=)
JP2024532485A5 (https=)
JP2018502050A5 (https=)
CN116789820A (zh) 一种新型免疫调节剂的开发和应用
WO2018156735A1 (en) Bispecific antibody for cancer immunotherapy
JP2022009816A5 (https=)
JP2019503686A5 (https=)
JP2024518378A5 (https=)
IL292358A (en) specific binding molecules
JP2024509910A5 (https=)
JP2021531834A5 (https=)
JP2025504909A5 (https=)
IL321809A (en) Binding molecules against a piwil1 peptide-hla complex