JP2022111148A5 - - Google Patents

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Publication number
JP2022111148A5
JP2022111148A5 JP2022084854A JP2022084854A JP2022111148A5 JP 2022111148 A5 JP2022111148 A5 JP 2022111148A5 JP 2022084854 A JP2022084854 A JP 2022084854A JP 2022084854 A JP2022084854 A JP 2022084854A JP 2022111148 A5 JP2022111148 A5 JP 2022111148A5
Authority
JP
Japan
Prior art keywords
icos
bispecific antibody
monomer
antibody
light chain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022084854A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022111148A (ja
Filing date
Publication date
Priority claimed from US15/623,314 external-priority patent/US10787518B2/en
Priority claimed from PCT/US2017/049497 external-priority patent/WO2018045110A1/en
Priority claimed from JP2019511464A external-priority patent/JP7080219B2/ja
Application filed filed Critical
Publication of JP2022111148A publication Critical patent/JP2022111148A/ja
Publication of JP2022111148A5 publication Critical patent/JP2022111148A5/ja
Pending legal-status Critical Current

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JP2022084854A 2016-08-30 2022-05-24 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 Pending JP2022111148A (ja)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US201662381239P 2016-08-30 2016-08-30
US62/381,239 2016-08-30
US201762456033P 2017-02-07 2017-02-07
US62/456,033 2017-02-07
US201762479723P 2017-03-31 2017-03-31
US62/479,723 2017-03-31
US15/623,314 2017-06-14
US15/623,314 US10787518B2 (en) 2016-06-14 2017-06-14 Bispecific checkpoint inhibitor antibodies
PCT/US2017/049497 WO2018045110A1 (en) 2016-08-30 2017-08-30 Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors
JP2019511464A JP7080219B2 (ja) 2016-08-30 2017-08-30 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2019511464A Division JP7080219B2 (ja) 2016-08-30 2017-08-30 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体

Publications (2)

Publication Number Publication Date
JP2022111148A JP2022111148A (ja) 2022-07-29
JP2022111148A5 true JP2022111148A5 (https=) 2023-02-20

Family

ID=65632988

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019511464A Active JP7080219B2 (ja) 2016-08-30 2017-08-30 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体
JP2022084854A Pending JP2022111148A (ja) 2016-08-30 2022-05-24 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2019511464A Active JP7080219B2 (ja) 2016-08-30 2017-08-30 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体

Country Status (12)

Country Link
EP (1) EP3507306B1 (https=)
JP (2) JP7080219B2 (https=)
KR (2) KR20230130174A (https=)
CN (1) CN110267990B (https=)
AU (1) AU2017321625A1 (https=)
CA (1) CA3035343A1 (https=)
DK (1) DK3507306T3 (https=)
HR (1) HRP20251424T1 (https=)
IL (1) IL265046B2 (https=)
MX (1) MX2023006786A (https=)
SG (1) SG11201901712YA (https=)
ZA (1) ZA201901752B (https=)

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RU2016107435A (ru) * 2013-09-13 2017-10-18 Дженентек, Инк. Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты
KR102170077B1 (ko) * 2018-05-21 2020-10-27 인하대학교 산학협력단 Prss14/st14의 자가분해 고리부분을 특이적으로 인식하는 단일클론항체 및 이의 용도
BR112021008060A2 (pt) * 2018-10-31 2021-11-23 Bioatla Inc Polipeptídeo, anticorpo anti-ctla4 ou fragmento de anticorpo, imunoconjugado, composição farmacêutica, dose única de composição farmacêutica, método de tratar câncer, e, kit para diagnóstico ou tratamento
AU2021256652A1 (en) * 2020-04-14 2022-11-03 Glaxosmithkline Intellectual Property Development Limited Combination treatment for cancer involving anti-ICOS and anti-PD1 antibodies, optionally further involving anti-tim3 antibodies
JP2023521227A (ja) * 2020-04-14 2023-05-23 グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド 癌の併用療法
CN116615442A (zh) * 2020-09-08 2023-08-18 优特力克斯有限公司 程序性细胞死亡1多肽变体
CN114195900B (zh) * 2020-09-17 2024-02-23 普米斯生物技术(珠海)有限公司 一种抗4-1bb/pd-l1双特异性抗体及其用途
KR102911451B1 (ko) * 2022-05-24 2026-01-09 건국대학교 글로컬산학협력단 Rps3 결합 단클론 항체 및 이의 용도

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8546543B2 (en) * 2004-11-12 2013-10-01 Xencor, Inc. Fc variants that extend antibody half-life
EP3255060A1 (en) * 2008-12-09 2017-12-13 F. Hoffmann-La Roche AG Anti-pd-l1 antibodies and their use to enhance t-cell function
US8637024B2 (en) * 2010-11-12 2014-01-28 The Rockefeller University Fusion antibodies for HIV therapy
UY34887A (es) * 2012-07-02 2013-12-31 Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos
KR102211837B1 (ko) * 2013-01-14 2021-02-03 젠코어 인코포레이티드 신규한 이형이량체 단백질
EP2970486B1 (en) * 2013-03-15 2018-05-16 Xencor, Inc. Modulation of t cells with bispecific antibodies and fc fusions
JP6594855B2 (ja) * 2013-03-15 2019-10-23 ゼンコア インコーポレイテッド ヘテロ二量体タンパク質
CN105722859B (zh) * 2013-07-25 2021-05-07 西托姆克斯治疗公司 多特异性抗体、多特异性可活化抗体及其使用方法
US10519251B2 (en) 2013-12-30 2019-12-31 Epimab Biotherapeutics, Inc. Fabs-in-tandem immunoglobulin and uses thereof
EP4245376A3 (en) * 2014-10-14 2023-12-13 Novartis AG Antibody molecules to pd-l1 and uses thereof
JP6668345B2 (ja) * 2014-11-21 2020-03-18 ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company 修飾された重鎖定常領域を含む抗体
EP3223907A2 (en) * 2014-11-26 2017-10-04 Xencor, Inc. Heterodimeric antibodies that bind cd3 and cd38
SI3242890T1 (sl) * 2015-01-08 2020-01-31 BioNTech SE Agonistična sredstva, ki vežejo receptorje TNF
CA2973720A1 (en) * 2015-01-14 2016-07-21 Compass Therapeutics Llc Multispecific immunomodulatory antigen-binding constructs
MA41414A (fr) * 2015-01-28 2017-12-05 Centre Nat Rech Scient Protéines de liaison agonistes d' icos

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