JP2022111148A5 - - Google Patents
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- Publication number
- JP2022111148A5 JP2022111148A5 JP2022084854A JP2022084854A JP2022111148A5 JP 2022111148 A5 JP2022111148 A5 JP 2022111148A5 JP 2022084854 A JP2022084854 A JP 2022084854A JP 2022084854 A JP2022084854 A JP 2022084854A JP 2022111148 A5 JP2022111148 A5 JP 2022111148A5
- Authority
- JP
- Japan
- Prior art keywords
- icos
- bispecific antibody
- monomer
- antibody
- light chain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (10)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662381239P | 2016-08-30 | 2016-08-30 | |
| US62/381,239 | 2016-08-30 | ||
| US201762456033P | 2017-02-07 | 2017-02-07 | |
| US62/456,033 | 2017-02-07 | ||
| US201762479723P | 2017-03-31 | 2017-03-31 | |
| US62/479,723 | 2017-03-31 | ||
| US15/623,314 | 2017-06-14 | ||
| US15/623,314 US10787518B2 (en) | 2016-06-14 | 2017-06-14 | Bispecific checkpoint inhibitor antibodies |
| PCT/US2017/049497 WO2018045110A1 (en) | 2016-08-30 | 2017-08-30 | Bispecific immunomodulatory antibodies that bind costimulatory and checkpoint receptors |
| JP2019511464A JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Division JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2022111148A JP2022111148A (ja) | 2022-07-29 |
| JP2022111148A5 true JP2022111148A5 (https=) | 2023-02-20 |
Family
ID=65632988
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Active JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
| JP2022084854A Pending JP2022111148A (ja) | 2016-08-30 | 2022-05-24 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019511464A Active JP7080219B2 (ja) | 2016-08-30 | 2017-08-30 | 共刺激受容体およびチェックポイント受容体に連結する二重特異性免疫調節抗体 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP3507306B1 (https=) |
| JP (2) | JP7080219B2 (https=) |
| KR (2) | KR20230130174A (https=) |
| CN (1) | CN110267990B (https=) |
| AU (1) | AU2017321625A1 (https=) |
| CA (1) | CA3035343A1 (https=) |
| DK (1) | DK3507306T3 (https=) |
| HR (1) | HRP20251424T1 (https=) |
| IL (1) | IL265046B2 (https=) |
| MX (1) | MX2023006786A (https=) |
| SG (1) | SG11201901712YA (https=) |
| ZA (1) | ZA201901752B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2016107435A (ru) * | 2013-09-13 | 2017-10-18 | Дженентек, Инк. | Композиции и способы обнаружения и количественного определения белка клеток-хозяев в клеточных линиях и рекомбинантные полипептидные продукты |
| KR102170077B1 (ko) * | 2018-05-21 | 2020-10-27 | 인하대학교 산학협력단 | Prss14/st14의 자가분해 고리부분을 특이적으로 인식하는 단일클론항체 및 이의 용도 |
| BR112021008060A2 (pt) * | 2018-10-31 | 2021-11-23 | Bioatla Inc | Polipeptídeo, anticorpo anti-ctla4 ou fragmento de anticorpo, imunoconjugado, composição farmacêutica, dose única de composição farmacêutica, método de tratar câncer, e, kit para diagnóstico ou tratamento |
| AU2021256652A1 (en) * | 2020-04-14 | 2022-11-03 | Glaxosmithkline Intellectual Property Development Limited | Combination treatment for cancer involving anti-ICOS and anti-PD1 antibodies, optionally further involving anti-tim3 antibodies |
| JP2023521227A (ja) * | 2020-04-14 | 2023-05-23 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | 癌の併用療法 |
| CN116615442A (zh) * | 2020-09-08 | 2023-08-18 | 优特力克斯有限公司 | 程序性细胞死亡1多肽变体 |
| CN114195900B (zh) * | 2020-09-17 | 2024-02-23 | 普米斯生物技术(珠海)有限公司 | 一种抗4-1bb/pd-l1双特异性抗体及其用途 |
| KR102911451B1 (ko) * | 2022-05-24 | 2026-01-09 | 건국대학교 글로컬산학협력단 | Rps3 결합 단클론 항체 및 이의 용도 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8546543B2 (en) * | 2004-11-12 | 2013-10-01 | Xencor, Inc. | Fc variants that extend antibody half-life |
| EP3255060A1 (en) * | 2008-12-09 | 2017-12-13 | F. Hoffmann-La Roche AG | Anti-pd-l1 antibodies and their use to enhance t-cell function |
| US8637024B2 (en) * | 2010-11-12 | 2014-01-28 | The Rockefeller University | Fusion antibodies for HIV therapy |
| UY34887A (es) * | 2012-07-02 | 2013-12-31 | Bristol Myers Squibb Company Una Corporacion Del Estado De Delaware | Optimización de anticuerpos que se fijan al gen de activación de linfocitos 3 (lag-3) y sus usos |
| KR102211837B1 (ko) * | 2013-01-14 | 2021-02-03 | 젠코어 인코포레이티드 | 신규한 이형이량체 단백질 |
| EP2970486B1 (en) * | 2013-03-15 | 2018-05-16 | Xencor, Inc. | Modulation of t cells with bispecific antibodies and fc fusions |
| JP6594855B2 (ja) * | 2013-03-15 | 2019-10-23 | ゼンコア インコーポレイテッド | ヘテロ二量体タンパク質 |
| CN105722859B (zh) * | 2013-07-25 | 2021-05-07 | 西托姆克斯治疗公司 | 多特异性抗体、多特异性可活化抗体及其使用方法 |
| US10519251B2 (en) | 2013-12-30 | 2019-12-31 | Epimab Biotherapeutics, Inc. | Fabs-in-tandem immunoglobulin and uses thereof |
| EP4245376A3 (en) * | 2014-10-14 | 2023-12-13 | Novartis AG | Antibody molecules to pd-l1 and uses thereof |
| JP6668345B2 (ja) * | 2014-11-21 | 2020-03-18 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | 修飾された重鎖定常領域を含む抗体 |
| EP3223907A2 (en) * | 2014-11-26 | 2017-10-04 | Xencor, Inc. | Heterodimeric antibodies that bind cd3 and cd38 |
| SI3242890T1 (sl) * | 2015-01-08 | 2020-01-31 | BioNTech SE | Agonistična sredstva, ki vežejo receptorje TNF |
| CA2973720A1 (en) * | 2015-01-14 | 2016-07-21 | Compass Therapeutics Llc | Multispecific immunomodulatory antigen-binding constructs |
| MA41414A (fr) * | 2015-01-28 | 2017-12-05 | Centre Nat Rech Scient | Protéines de liaison agonistes d' icos |
-
2017
- 2017-08-30 CN CN201780060900.7A patent/CN110267990B/zh active Active
- 2017-08-30 KR KR1020237029969A patent/KR20230130174A/ko not_active Ceased
- 2017-08-30 CA CA3035343A patent/CA3035343A1/en active Pending
- 2017-08-30 KR KR1020197009280A patent/KR102575681B1/ko active Active
- 2017-08-30 JP JP2019511464A patent/JP7080219B2/ja active Active
- 2017-08-30 IL IL265046A patent/IL265046B2/en unknown
- 2017-08-30 DK DK17765002.5T patent/DK3507306T3/da active
- 2017-08-30 HR HRP20251424TT patent/HRP20251424T1/hr unknown
- 2017-08-30 EP EP17765002.5A patent/EP3507306B1/en active Active
- 2017-08-30 SG SG11201901712YA patent/SG11201901712YA/en unknown
- 2017-08-30 AU AU2017321625A patent/AU2017321625A1/en not_active Abandoned
-
2019
- 2019-02-27 MX MX2023006786A patent/MX2023006786A/es unknown
- 2019-03-20 ZA ZA2019/01752A patent/ZA201901752B/en unknown
-
2022
- 2022-05-24 JP JP2022084854A patent/JP2022111148A/ja active Pending
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