JP2022081492A5 - - Google Patents

Download PDF

Info

Publication number
JP2022081492A5
JP2022081492A5 JP2022021751A JP2022021751A JP2022081492A5 JP 2022081492 A5 JP2022081492 A5 JP 2022081492A5 JP 2022021751 A JP2022021751 A JP 2022021751A JP 2022021751 A JP2022021751 A JP 2022021751A JP 2022081492 A5 JP2022081492 A5 JP 2022081492A5
Authority
JP
Japan
Prior art keywords
cancer
vaccine
protein
fragment
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2022021751A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022081492A (ja
Filing date
Publication date
Priority claimed from PCT/EP2016/060897 external-priority patent/WO2017194170A1/en
Application filed filed Critical
Publication of JP2022081492A publication Critical patent/JP2022081492A/ja
Publication of JP2022081492A5 publication Critical patent/JP2022081492A5/ja
Priority to JP2024045130A priority Critical patent/JP2024096712A/ja
Priority to JP2024103724A priority patent/JP2024160216A/ja
Pending legal-status Critical Current

Links

JP2022021751A 2016-05-13 2022-02-16 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法 Pending JP2022081492A (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2024045130A JP2024096712A (ja) 2016-05-13 2024-03-21 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法
JP2024103724A JP2024160216A (ja) 2016-05-13 2024-06-27 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/EP2016/060897 WO2017194170A1 (en) 2016-05-13 2016-05-13 Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
EPPCT/EP2016/060897 2016-05-13
PCT/EP2017/061196 WO2017194610A1 (en) 2016-05-13 2017-05-10 Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
JP2018559794A JP7529381B2 (ja) 2016-05-13 2017-05-10 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2018559794A Division JP7529381B2 (ja) 2016-05-13 2017-05-10 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024045130A Division JP2024096712A (ja) 2016-05-13 2024-03-21 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法

Publications (2)

Publication Number Publication Date
JP2022081492A JP2022081492A (ja) 2022-05-31
JP2022081492A5 true JP2022081492A5 (https=) 2022-12-16

Family

ID=55971007

Family Applications (5)

Application Number Title Priority Date Filing Date
JP2018559794A Active JP7529381B2 (ja) 2016-05-13 2017-05-10 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法
JP2022021751A Pending JP2022081492A (ja) 2016-05-13 2022-02-16 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法
JP2024045130A Pending JP2024096712A (ja) 2016-05-13 2024-03-21 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法
JP2024069742A Pending JP2024112805A (ja) 2016-05-13 2024-04-23 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法
JP2024103724A Pending JP2024160216A (ja) 2016-05-13 2024-06-27 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2018559794A Active JP7529381B2 (ja) 2016-05-13 2017-05-10 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2024045130A Pending JP2024096712A (ja) 2016-05-13 2024-03-21 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法
JP2024069742A Pending JP2024112805A (ja) 2016-05-13 2024-04-23 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法
JP2024103724A Pending JP2024160216A (ja) 2016-05-13 2024-06-27 免疫療法に対するタンパク質又はタンパク質のフラグメントの有用性を予測するための方法

Country Status (27)

Country Link
US (2) US12153041B2 (https=)
EP (3) EP4411376A3 (https=)
JP (5) JP7529381B2 (https=)
KR (3) KR20220020993A (https=)
CN (1) CN109073637A (https=)
AU (2) AU2017264546B2 (https=)
BR (1) BR112018073221A2 (https=)
CA (1) CA3022654A1 (https=)
CY (1) CY1123520T1 (https=)
DK (2) DK3792628T3 (https=)
ES (2) ES2826480T3 (https=)
FI (1) FI3792628T3 (https=)
HR (2) HRP20240704T1 (https=)
HU (2) HUE067497T2 (https=)
IL (2) IL300841A (https=)
LT (2) LT3455625T (https=)
MA (1) MA43794B1 (https=)
MD (1) MD3455625T2 (https=)
MX (2) MX393653B (https=)
PL (2) PL3455625T3 (https=)
PT (2) PT3792628T (https=)
RS (2) RS65568B1 (https=)
SG (1) SG11201808495SA (https=)
SI (2) SI3792628T1 (https=)
SM (2) SMT202400232T1 (https=)
WO (2) WO2017194170A1 (https=)
ZA (1) ZA201805809B (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL260030B2 (en) 2016-01-08 2025-12-01 Nykode Therapeutics ASA Therapeutic anticancer neoepitope vaccine
WO2017194170A1 (en) 2016-05-13 2017-11-16 Biontech Rna Pharmaceuticals Gmbh Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
EP3933408A1 (en) 2017-05-30 2022-01-05 Nant Holdings IP LLC Circulating tumor cell enrichment using neoepitopes
JP6857930B2 (ja) * 2018-02-15 2021-04-14 国立大学法人旭川医科大学 がん抗原ペプチド
CA3106564A1 (en) 2018-07-26 2020-01-30 Frame Pharmaceuticals B.V. Cancer vaccines for breast cancer
US20220349010A1 (en) 2018-07-26 2022-11-03 Frame Pharmaceuticals B.V. Method of preparing subject-specific immunogenic compositions based on a neo open-reading-frame peptide database
CN109021062B (zh) * 2018-08-06 2021-08-20 倍而达药业(苏州)有限公司 一种肿瘤新抗原的筛选方法
CN111621564B (zh) * 2019-02-28 2022-03-25 武汉大学 一种鉴定有效肿瘤新抗原的方法
TWI894138B (zh) * 2019-03-06 2025-08-21 美商西雅圖項目公司 利用ii 類mhc 模型鑑別新抗原
CN110534156B (zh) * 2019-09-02 2022-06-17 深圳市新合生物医疗科技有限公司 一种提取免疫治疗新抗原的方法及系统
CN111487399B (zh) * 2020-03-26 2021-09-17 湖南师范大学 一种蛋白分子标记在鱼类生殖细胞发育研究中的应用
WO2023025404A1 (en) 2021-08-24 2023-03-02 BioNTech SE In vitro transcription technologies
WO2024083345A1 (en) 2022-10-21 2024-04-25 BioNTech SE Methods and uses associated with liquid compositions
WO2025202937A1 (en) 2024-03-26 2025-10-02 BioNTech SE Cancer vaccines

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2766205B1 (fr) * 1997-07-16 2002-08-30 Inst Nat Sante Rech Med Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede
DK1276896T3 (da) * 2000-04-28 2010-10-18 Mannkind Corp Epitop-synkronisering i antigen-præsenterende celler
CA2415902A1 (en) 2000-07-10 2002-01-17 Xencor Protein design automation for designing protein libraries with altered immunogenicity
JP4900884B2 (ja) * 2000-07-31 2012-03-21 株式会社グリーンペプタイド 腫瘍抗原
DE10225139A1 (de) 2002-05-29 2004-02-26 Immatics Biotechnologies Gmbh Verfahren zur Identifizierung von immunreaktiven Peptiden
TW200413539A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Genes and polypeptides relating to prostate cancers
WO2006105255A2 (en) * 2005-03-29 2006-10-05 The Board Of Trustees Of The University Of Illinois Cancer vaccines and therapeutic methods
JP2009273377A (ja) * 2008-05-12 2009-11-26 Igaku Seibutsugaku Kenkyusho:Kk Mhcクラスi分子と結合し癌細胞の表面に表出されるペプチド候補の選択方法
TW201000119A (en) * 2008-06-10 2010-01-01 Oncotherapy Science Inc MYBL2 epitope peptides and vaccines containing the same
RS53782B1 (sr) * 2008-10-01 2015-06-30 Immatics Biotechnologies Gmbh Preparati tumor-asociranih peptida i odgovarajuća antikancerska vakcina za tretman glioblastoma (gbm) i drugih kancera
CA2755983A1 (en) 2009-03-23 2010-09-30 The Walter And Eliza Hall Institute Of Medical Research Compounds and methods for modulating an immune response
AU2010310468A1 (en) * 2009-10-23 2012-05-24 Mannkind Corporation Cancer immunotherapy and method of treatment
PL3892295T3 (pl) 2011-05-24 2023-07-24 BioNTech SE Zindywidualizowane szczepionki przeciwnowotworowe
WO2012159643A1 (en) 2011-05-24 2012-11-29 Biontech Ag Individualized vaccines for cancer
EP2714730A1 (en) * 2011-06-01 2014-04-09 INSERM (Institut National de la Santé et de la Recherche Médicale) Novel antigen peptide and uses thereof
GB201319446D0 (en) 2013-11-04 2013-12-18 Immatics Biotechnologies Gmbh Personalized immunotherapy against several neuronal and brain tumors
ES2970865T3 (es) 2015-12-16 2024-05-31 Gritstone Bio Inc Identificación, fabricación y uso de neoantígenos
WO2017194170A1 (en) 2016-05-13 2017-11-16 Biontech Rna Pharmaceuticals Gmbh Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
CA3060569A1 (en) 2017-04-19 2018-10-25 Gritstone Oncology, Inc. Neoantigen identification, manufacture, and use
AU2018279627B2 (en) 2017-06-09 2023-08-10 Seattle Project Corp. Neoantigen identification, manufacture, and use
US20200363414A1 (en) 2017-09-05 2020-11-19 Gritstone Oncology, Inc. Neoantigen Identification for T-Cell Therapy
EP4576103A3 (en) 2017-10-10 2025-08-27 Gritstone bio, Inc. Neoantigen identification using hotspots
CN111630602A (zh) 2017-11-22 2020-09-04 磨石肿瘤生物技术公司 减少新抗原的接合表位呈递
EP3759131A4 (en) 2018-02-27 2021-12-01 Gritstone bio, Inc. NEOANTIGEN IDENTIFICATION WITH PAN ALLELE MODELS

Similar Documents

Publication Publication Date Title
JP2022081492A5 (https=)
Kawakami et al. Human tumor antigens recognized by T-cells
JP2021517810A5 (https=)
Kawashima et al. Identification of HLA-A3-restricted cytotoxic T lymphocyte epitopes from carcinoembryonic antigen and HER-2/neu by primary in vitro immunization with peptide-pulsed dendritic cells
JP2021036867A5 (https=)
JP2019520591A5 (https=)
IL300841A (en) Methods for predicting the usefulness of proteins or protein fragments for immunotherapy
CN109021062A (zh) 一种肿瘤新抗原的筛选方法
Willimsky et al. In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo
Aguilar-Gurrieri et al. Alanine-based spacers promote an efficient antigen processing and presentation in neoantigen polypeptide vaccines
US9720000B2 (en) Targeted identification of immunogenic peptides
CN109234283B (zh) 肿瘤相关基因cdh1突变短肽及其应用
Lown et al. Magnetic bead-immobilized mammalian cells are effective targets to enrich ligand-displaying yeast
CN107987164A (zh) 雌激素受体ER-α36抗原多肽及其单克隆抗体
Apostolopoulos et al. The immunogenicity of MUC1 peptides and fusion protein
CN109758590B (zh) 一种用于筛选人前列腺癌肿瘤抗原表位肽的方法
Durrant et al. Production of monoclonal antibodies recognising the peptide core of MUC2 intestinal mucin
Hashemzadeh et al. Novel predicted B-cell epitopes of PSMA for development of prostate cancer vaccine
CN103728456A (zh) 胸腺嘧啶核苷激酶的elisa诊断试剂盒
CN102973950B (zh) Prame、wt1双价肿瘤dna疫苗
Zahraei et al. In silico design of a multi-epitope vaccine against the triple negative breast cancer
JP2012072167A (ja) 免疫源性ペプチドの標的特異的同定方法
Xing et al. Peptide epitopes in breast cancer mucins
Dunphy et al. New approaches to identification of antigenic candidates for future prostate cancer immunotherapy
Brown et al. Recognition of carcinoembryonic antigen peptide and heteroclitic peptide by peripheral blood T lymphocytes