JP2022046676A5 - - Google Patents
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- JP2022046676A5 JP2022046676A5 JP2021212106A JP2021212106A JP2022046676A5 JP 2022046676 A5 JP2022046676 A5 JP 2022046676A5 JP 2021212106 A JP2021212106 A JP 2021212106A JP 2021212106 A JP2021212106 A JP 2021212106A JP 2022046676 A5 JP2022046676 A5 JP 2022046676A5
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- Prior art keywords
- growth factor
- protein
- factor
- therapeutic protein
- water
- Prior art date
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| US8809501B2 (en) | 2009-07-27 | 2014-08-19 | Baxter International Inc. | Nucleophilic catalysts for oxime linkage |
| DK2598172T3 (da) * | 2010-07-30 | 2019-07-01 | Baxalta GmbH | Nukleofile katalysatorer til oximforbindelse |
| EP2654794B8 (en) | 2010-12-22 | 2020-04-22 | Baxalta GmbH | Materials and methods for conjugating a water soluble fatty acid derivative to a protein |
| GB2516388A (en) * | 2012-04-16 | 2015-01-21 | Cantab Biopharmaceuticals Patents Ltd | Optimised subcutaneous therapeutic agents |
| AU2013204754C1 (en) * | 2012-05-16 | 2018-10-11 | Takeda Pharmaceutical Company Limited | Nucleophilic Catalysts for Oxime Linkage |
| MA39711A (fr) * | 2014-04-03 | 2015-10-08 | Nektar Therapeutics | Conjugués d'une fraction d'il-15 et d'un polymère |
| MX2018004296A (es) | 2015-10-08 | 2018-08-01 | Nektar Therapeutics | Combinacion de un agonista selectivo de il-2rbeta y un agonista il-15 de accion prolongada. |
| US20170349644A1 (en) * | 2015-12-03 | 2017-12-07 | Baxalta Incorporated | Factor viii with extended half-life and reduced ligand-binding properties |
| EP3487538A1 (en) | 2016-07-22 | 2019-05-29 | Nektar Therapeutics | Conjugates of a factor viii moiety having an oxime-containing linkage |
| WO2018213341A1 (en) | 2017-05-15 | 2018-11-22 | Nektar Therapeutics | Long-acting interleukin-15 receptor agonists and related immunotherapeutic compositions and methods |
| SG11202107497XA (en) | 2019-01-23 | 2021-08-30 | Regeneron Pharma | Treatment of ophthalmic conditions with angiopoietin-like 7 (angptl7) inhibitors |
| US11845989B2 (en) | 2019-01-23 | 2023-12-19 | Regeneron Pharmaceuticals, Inc. | Treatment of ophthalmic conditions with angiopoietin-like 7 (ANGPTL7) inhibitors |
| EP4298219A1 (en) | 2021-02-26 | 2024-01-03 | Regeneron Pharmaceuticals, Inc. | Treatment of inflammation with glucocorticoids and angiopoietin-like 7 (angptl7) inhibitors |
| WO2025133203A1 (en) * | 2023-12-22 | 2025-06-26 | Pam Theragnostics Gmbh | Compounds and methods for a long-lasting pam |
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