JP2022040131A5 - - Google Patents

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Publication number
JP2022040131A5
JP2022040131A5 JP2021202636A JP2021202636A JP2022040131A5 JP 2022040131 A5 JP2022040131 A5 JP 2022040131A5 JP 2021202636 A JP2021202636 A JP 2021202636A JP 2021202636 A JP2021202636 A JP 2021202636A JP 2022040131 A5 JP2022040131 A5 JP 2022040131A5
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JP
Japan
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formula
cpp
alkyl
compound
ceremony
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JP2021202636A
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English (en)
Japanese (ja)
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JP2022040131A (ja
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Priority claimed from PCT/US2015/000280 external-priority patent/WO2016108930A2/en
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Publication of JP2022040131A publication Critical patent/JP2022040131A/ja
Publication of JP2022040131A5 publication Critical patent/JP2022040131A5/ja
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JP2021202636A 2014-12-31 2021-12-14 アンチセンス抗細菌性化合物および方法 Withdrawn JP2022040131A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201462098713P 2014-12-31 2014-12-31
US62/098,713 2014-12-31
PCT/US2015/000280 WO2016108930A2 (en) 2014-12-31 2015-12-23 Antisense antibacterial compounds and methods
JP2017535019A JP6994941B2 (ja) 2014-12-31 2015-12-23 アンチセンス抗細菌性化合物および方法

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2017535019A Division JP6994941B2 (ja) 2014-12-31 2015-12-23 アンチセンス抗細菌性化合物および方法

Publications (2)

Publication Number Publication Date
JP2022040131A JP2022040131A (ja) 2022-03-10
JP2022040131A5 true JP2022040131A5 (https=) 2022-07-07

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ID=56285129

Family Applications (2)

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JP2017535019A Active JP6994941B2 (ja) 2014-12-31 2015-12-23 アンチセンス抗細菌性化合物および方法
JP2021202636A Withdrawn JP2022040131A (ja) 2014-12-31 2021-12-14 アンチセンス抗細菌性化合物および方法

Family Applications Before (1)

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JP2017535019A Active JP6994941B2 (ja) 2014-12-31 2015-12-23 アンチセンス抗細菌性化合物および方法

Country Status (7)

Country Link
US (1) US11293024B2 (https=)
EP (1) EP3240794A4 (https=)
JP (2) JP6994941B2 (https=)
AU (1) AU2015372560B2 (https=)
CA (2) CA3249464A1 (https=)
HK (1) HK1246303A1 (https=)
WO (1) WO2016108930A2 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9790495B2 (en) 2014-05-16 2017-10-17 Oregon State University Antisense antibacterial compounds and methods
AU2015264449B2 (en) 2014-05-19 2022-05-05 Board Of Regents, The University Of Texas System Antisense antibacterial compounds and methods
CA3249464A1 (en) 2014-12-31 2025-11-29 Univ Texas Antisense antibacterial compounds and methods
AU2016379402B2 (en) 2015-12-23 2023-01-12 Board Of Regents, The University Of Texas System Antisense antibacterial compounds and methods
AU2016379399B2 (en) 2015-12-23 2022-12-08 Board Of Regents, The University Of Texas System Antisense antibacterial compounds and methods
WO2020035619A1 (en) * 2018-08-17 2020-02-20 Centre National De La Recherche Scientifique (Cnrs) Rna-based biocontrol methods to protect plants against pathogenic bacteria and / or promote beneficial effects of symbiotic and commensal bacteria
GB2579253A (en) 2018-11-28 2020-06-17 Pedanius Therapeutics Ltd Antibacterial antisense agents

Family Cites Families (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5668616A (en) * 1979-11-08 1981-06-09 Yukio Kimura Preparation of antibiotic composition
US5217866A (en) 1985-03-15 1993-06-08 Anti-Gene Development Group Polynucleotide assay reagent and method
US5506337A (en) 1985-03-15 1996-04-09 Antivirals Inc. Morpholino-subunit combinatorial library and method
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US5521063A (en) 1985-03-15 1996-05-28 Antivirals Inc. Polynucleotide reagent containing chiral subunits and methods of use
US5185444A (en) 1985-03-15 1993-02-09 Anti-Gene Deveopment Group Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages
JP3022967B2 (ja) 1985-03-15 2000-03-21 アンチバイラルズ インコーポレイテッド 立体規則性ポリヌクレオチド結合ポリマー
US5166315A (en) 1989-12-20 1992-11-24 Anti-Gene Development Group Sequence-specific binding polymers for duplex nucleic acids
WO1993001286A2 (en) 1991-06-28 1993-01-21 Massachusetts Institute Of Technology Localized oligonucleotide therapy
ATE330644T1 (de) 1995-12-18 2006-07-15 Angiotech Biomaterials Corp Vernetzten polymerisatmassen und verfahren für ihre verwendung
US6245747B1 (en) 1996-03-12 2001-06-12 The Board Of Regents Of The University Of Nebraska Targeted site specific antisense oligodeoxynucleotide delivery method
WO1998050557A1 (en) * 1997-05-02 1998-11-12 University Of Guelph Proteins involved in the synthesis and assembly of core lipopolysaccharide of pseudomonas aeruginosa
WO2000015265A1 (en) * 1998-09-16 2000-03-23 Vitagenix, Inc. Compositions and methods of use of uptake mechanisms for diagnostic and therapeutic applications of oligonucleotides targeting bacteria
US20040033972A1 (en) * 2000-12-20 2004-02-19 Horwitz Marcus A. Treatment of mycobacterium tuberculosis with antisense polynucleotides
US20060241075A1 (en) 2001-05-18 2006-10-26 Sirna Therapeutics, Inc. RNA interference mediated inhibition of desmoglein gene expression using short interfering nucleic acid (siNA)
US20040029129A1 (en) 2001-10-25 2004-02-12 Liangsu Wang Identification of essential genes in microorganisms
US6965025B2 (en) 2001-12-10 2005-11-15 Isis Pharmaceuticals, Inc. Antisense modulation of connective tissue growth factor expression
AU2004231740A1 (en) 2003-04-17 2004-11-04 The Trustees Of Columbia University In The City Ofnew York Desmoglein 4 is a novel gene involved in hair growth
CA2523672C (en) 2003-04-29 2012-07-17 Avi Biopharma, Inc. Compositions for enhancing transport of molecules into cells
US20050288246A1 (en) 2004-05-24 2005-12-29 Iversen Patrick L Peptide conjugated, inosine-substituted antisense oligomer compound and method
ATE510914T1 (de) 2004-07-02 2011-06-15 Avi Biopharma Inc Antisinn antibakterielle verfahren und verbindungen
US20060263798A1 (en) 2005-02-11 2006-11-23 International Business Machines Corporation System and method for identification of MicroRNA precursor sequences and corresponding mature MicroRNA sequences from genomic sequences
US7790694B2 (en) 2005-07-13 2010-09-07 Avi Biopharma Inc. Antisense antibacterial method and compound
US8067571B2 (en) * 2005-07-13 2011-11-29 Avi Biopharma, Inc. Antibacterial antisense oligonucleotide and method
CA2614191C (en) 2005-07-13 2015-06-30 Avi Biopharma, Inc. Antisense antibacterial method and compound
WO2007025016A1 (en) 2005-08-25 2007-03-01 Texas Tech University System Inhibition of metallo-beta-lactamase by double-stranded dna
EP3443976A1 (en) * 2007-06-29 2019-02-20 Sarepta Therapeutics, Inc. Tissue specific peptide conjugates and methods
US20100016215A1 (en) * 2007-06-29 2010-01-21 Avi Biopharma, Inc. Compound and method for treating myotonic dystrophy
MX2010004955A (es) 2007-11-15 2010-06-30 Avi Biopharma Inc Metodo de sintesis de oligomeros de morfolina.
US8299206B2 (en) 2007-11-15 2012-10-30 Avi Biopharma, Inc. Method of synthesis of morpholino oligomers
US8076476B2 (en) 2007-11-15 2011-12-13 Avi Biopharma, Inc. Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits
WO2009139635A1 (en) * 2008-05-15 2009-11-19 Prosensa Technologies B.V. Polymyxin derivatives and uses thereof
WO2010134939A2 (en) * 2008-12-19 2010-11-25 Zirus, Inc. Mammalian genes involved in infection
US20110269665A1 (en) 2009-06-26 2011-11-03 Avi Biopharma, Inc. Compound and method for treating myotonic dystrophy
WO2011018798A2 (en) 2009-08-14 2011-02-17 Indian Association For The Cultivation Of Science Morpholino-based antisense agent
WO2012031243A2 (en) 2010-09-03 2012-03-08 Avi Biopharma, Inc. dsRNA MOLECULES COMPRISING OLIGONUCLEOTIDE ANALOGS HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS
RS55610B1 (sr) 2010-09-30 2017-06-30 Nippon Shinyaku Co Ltd Derivat morfolino nukleinske kiseline
EP3067420A1 (en) 2010-11-12 2016-09-14 Sarepta Therapeutics, Inc. Antisense antibacterial compounds and methods
US20120213663A1 (en) 2011-02-23 2012-08-23 King Fahd University Of Petroleum And Minerals Method of removing e. coli bacteria from an aqueous solution
US9161948B2 (en) * 2011-05-05 2015-10-20 Sarepta Therapeutics, Inc. Peptide oligonucleotide conjugates
WO2012150960A1 (en) 2011-05-05 2012-11-08 Avi Biopharma, Inc. Peptide oligonucleotide conjugates
KR101317263B1 (ko) 2011-07-05 2013-10-10 (주)지노첵 리얼타임 ｐｃｒ을 이용한 카바페넴 내성 장내균 검사 방법 및 키트
WO2013011072A1 (en) 2011-07-20 2013-01-24 INSERM (Institut National de la Santé et de la Recherche Médicale) Carbapenemase and antibacterial treatment
EA202090338A1 (ru) * 2011-11-18 2021-04-30 Сарепта Терапьютикс, Инк. Функционально-модифицированные олигонуклеотиды и их субъединицы
KR101450751B1 (ko) * 2012-07-05 2014-10-16 서강대학교산학협력단 미생물을 이용한 지방산 제조 방법
US9790495B2 (en) 2014-05-16 2017-10-17 Oregon State University Antisense antibacterial compounds and methods
AU2015264449B2 (en) 2014-05-19 2022-05-05 Board Of Regents, The University Of Texas System Antisense antibacterial compounds and methods
CA3249464A1 (en) 2014-12-31 2025-11-29 Univ Texas Antisense antibacterial compounds and methods
AU2016379399B2 (en) 2015-12-23 2022-12-08 Board Of Regents, The University Of Texas System Antisense antibacterial compounds and methods
AU2016379402B2 (en) 2015-12-23 2023-01-12 Board Of Regents, The University Of Texas System Antisense antibacterial compounds and methods

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