JP2022031784A5 - - Google Patents
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- JP2022031784A5 JP2022031784A5 JP2021190474A JP2021190474A JP2022031784A5 JP 2022031784 A5 JP2022031784 A5 JP 2022031784A5 JP 2021190474 A JP2021190474 A JP 2021190474A JP 2021190474 A JP2021190474 A JP 2021190474A JP 2022031784 A5 JP2022031784 A5 JP 2022031784A5
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- chimeric antigen
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Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023098770A JP2023116716A (ja) | 2018-04-12 | 2023-06-15 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
| JP2025051295A JP2025098166A (ja) | 2018-04-12 | 2025-03-26 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810326346.9A CN110372796B (zh) | 2018-04-12 | 2018-04-12 | 靶向bcma的嵌合抗原受体及其制法和应用 |
| CN201810326346.9 | 2018-04-12 | ||
| JP2020531444A JP7148611B2 (ja) | 2018-04-12 | 2019-04-02 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
| PCT/CN2019/081064 WO2019196713A1 (zh) | 2018-04-12 | 2019-04-02 | 靶向bcma的嵌合抗原受体及其制法和应用 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531444A Division JP7148611B2 (ja) | 2018-04-12 | 2019-04-02 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023098770A Division JP2023116716A (ja) | 2018-04-12 | 2023-06-15 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2022031784A JP2022031784A (ja) | 2022-02-22 |
| JP2022031784A5 true JP2022031784A5 (https=) | 2022-09-15 |
| JP7299294B2 JP7299294B2 (ja) | 2023-06-27 |
Family
ID=68162957
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531444A Active JP7148611B2 (ja) | 2018-04-12 | 2019-04-02 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
| JP2021190474A Active JP7299294B2 (ja) | 2018-04-12 | 2021-11-24 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
| JP2023098770A Pending JP2023116716A (ja) | 2018-04-12 | 2023-06-15 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
| JP2025051295A Pending JP2025098166A (ja) | 2018-04-12 | 2025-03-26 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020531444A Active JP7148611B2 (ja) | 2018-04-12 | 2019-04-02 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023098770A Pending JP2023116716A (ja) | 2018-04-12 | 2023-06-15 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
| JP2025051295A Pending JP2025098166A (ja) | 2018-04-12 | 2025-03-26 | Ｂｃｍａを標的とするキメラ抗原受容体およびその製造方法と使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US11142581B2 (https=) |
| EP (1) | EP3778651A4 (https=) |
| JP (4) | JP7148611B2 (https=) |
| KR (1) | KR20200142036A (https=) |
| CN (3) | CN116836297A (https=) |
| AU (2) | AU2019251016B2 (https=) |
| CA (1) | CA3095827A1 (https=) |
| SG (1) | SG11202009962UA (https=) |
| WO (1) | WO2019196713A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116836297A (zh) * | 2018-04-12 | 2023-10-03 | 上海赛比曼生物科技有限公司 | 靶向bcma的嵌合抗原受体及其制法和应用 |
| CN111333732B (zh) * | 2019-12-17 | 2023-02-28 | 中国药科大学 | 一种靶向人bcma且激活nk细胞的双特异性抗体的制备及其应用 |
| KR102371151B1 (ko) * | 2020-03-13 | 2022-03-07 | 주식회사 큐로셀 | 항-bcma 결합 영역, 이를 포함하는 융합단백질, 및 이를 포함하는 조성물 |
| CN112851815B (zh) * | 2020-03-17 | 2023-08-08 | 西安宇繁生物科技有限责任公司 | 抗bcma抗体或其抗原结合片段及其制备方法和应用 |
| CN113527507A (zh) * | 2020-04-16 | 2021-10-22 | 上海赛比曼生物科技有限公司 | 靶向cd22的嵌合抗原受体及其制法和应用 |
| CN113637073B (zh) * | 2020-05-11 | 2024-04-12 | 上海赛比曼生物科技有限公司 | Bcma抗体及其制备和应用 |
| CN112251412B (zh) * | 2020-10-12 | 2023-03-28 | 汤朝阳 | 一种靶向bcma的嵌合抗原受体t细胞及其应用 |
| EP4255936A4 (en) * | 2020-12-02 | 2025-01-22 | Shanghai AbelZeta Ltd. | Bcma-targeted chimeric antigen receptors |
| US20240000839A1 (en) * | 2020-12-02 | 2024-01-04 | Shanghai Cellular Biopharmaceutical Group Ltd. | Bcma-targeted chimeric antigen receptors |
| KR20230122618A (ko) | 2020-12-21 | 2023-08-22 | 알로젠 테라퓨틱스 인코포레이티드 | 프로테아제 활성화 cd45-게이트 car |
| CN113173991B (zh) * | 2020-12-31 | 2023-03-28 | 北京艺妙神州医药科技有限公司 | 一种抗bcma的抗体及其应用 |
| CA3204417A1 (en) | 2021-01-29 | 2022-08-04 | Allogene Therapeutics, Inc. | Knockdown or knockout of one or more of tap2, nlrc5, ?2m, trac, rfx5, rfxap and rfxank to mitigate t cell recognition of allogeneic cell products |
| US20240059782A1 (en) * | 2022-03-01 | 2024-02-22 | Agilent Technologies, Inc. | Anti-human b cell maturation antigen (bcma) antibodies and their use in immunohistochemistry (ihc) |
| CA3261440A1 (en) | 2022-07-29 | 2024-02-01 | Allogene Therapeutics, Inc. | MODIFIED CELLS WITH REDUCED GENE EXPRESSION TO MITIGATE RECOGNITION BY IMMUNE CELLS |
| CN116251188A (zh) * | 2023-01-09 | 2023-06-13 | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | Stat1抑制剂在制备b细胞淋巴癌放射增敏药物中的应用及该药物 |
| KR20250131823A (ko) * | 2023-03-31 | 2025-09-03 | 아벨제타 인크. | Cd20 및 bcma를 표적화하는 이중특이적 키메라 항원 수용체 |
| CN116444669B (zh) * | 2023-04-04 | 2024-02-13 | 科弈(浙江)药业科技有限公司 | 靶向bcma car-t细胞人源化抗体 |
| AU2024372734A1 (en) | 2023-10-30 | 2026-04-16 | Allogene Therapeutics, Inc. | Engineered cells |
| CN119119274A (zh) * | 2024-09-26 | 2024-12-13 | 北京昌盛鸿途生物科技有限公司 | 一种靶向bcma的cart细胞及其应用 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5703055A (en) | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5399346A (en) | 1989-06-14 | 1995-03-21 | The United States Of America As Represented By The Department Of Health And Human Services | Gene therapy |
| US5585362A (en) | 1989-08-22 | 1996-12-17 | The Regents Of The University Of Michigan | Adenovirus vectors for gene therapy |
| US5350674A (en) | 1992-09-04 | 1994-09-27 | Becton, Dickinson And Company | Intrinsic factor - horse peroxidase conjugates and a method for increasing the stability thereof |
| HK1047109A1 (zh) | 1999-10-15 | 2003-02-07 | University Of Massachusetts | 作为指定基因干预工具的rna干预轨迹基因 |
| US6326193B1 (en) | 1999-11-05 | 2001-12-04 | Cambria Biosciences, Llc | Insect control agent |
| AU2001275474A1 (en) | 2000-06-12 | 2001-12-24 | Akkadix Corporation | Materials and methods for the control of nematodes |
| KR101972446B1 (ko) * | 2011-05-27 | 2019-04-25 | 글락소 그룹 리미티드 | Ｂｃｍａ（ｃｄ２６９／ｔｎｆｒｓｆ１７）결합 단백질 |
| TWI679212B (zh) * | 2011-11-15 | 2019-12-11 | 美商安進股份有限公司 | 針對ｂｃｍａ之e3以及ｃｄ３的結合分子 |
| RU2766608C2 (ru) * | 2012-04-11 | 2022-03-15 | Дзе Юнайтед Стейтс Оф Америка, Эз Репрезентед Бай Дзе Секретари, Департмент Оф Хелс Энд Хьюман Сёрвисез | Химерные антигенные рецепторы, нацеленные на антиген созревания b-клеток |
| EP3131927B8 (en) * | 2014-04-14 | 2020-12-23 | Cellectis | Bcma (cd269) specific chimeric antigen receptors for cancer immunotherapy |
| ES2878449T3 (es) * | 2014-07-24 | 2021-11-18 | 2Seventy Bio Inc | Receptores antigénicos quiméricos de BCMA |
| HRP20191873T1 (hr) * | 2014-12-12 | 2020-01-24 | Bluebird Bio, Inc. | Kimerni antigenski receptori |
| GB201503742D0 (en) * | 2015-03-05 | 2015-04-22 | Ucl Business Plc | Chimeric antigen receptor |
| US10294304B2 (en) * | 2015-04-13 | 2019-05-21 | Pfizer Inc. | Chimeric antigen receptors targeting B-cell maturation antigen |
| WO2018028647A1 (en) * | 2016-08-10 | 2018-02-15 | Legend Biotech Usa Inc. | Chimeric antigen receptors targeting bcma and methods of use thereof |
| CN105384825B (zh) * | 2015-08-11 | 2018-06-01 | 南京传奇生物科技有限公司 | 一种基于单域抗体的双特异性嵌合抗原受体及其应用 |
| WO2017072716A1 (en) * | 2015-10-30 | 2017-05-04 | Glaxosmithkline Intellectual Property Development Limited | Prognostic method |
| KR20230148844A (ko) * | 2016-03-29 | 2023-10-25 | 유니버시티 오브 써던 캘리포니아 | 암을 표적하는 키메라 항원 수용체 |
| WO2017210617A2 (en) | 2016-06-02 | 2017-12-07 | Porter, David, L. | Therapeutic regimens for chimeric antigen receptor (car)- expressing cells |
| SG10202012157QA (en) * | 2016-06-07 | 2021-01-28 | Max Delbrueck Centrum Fuer Molekulare Medizin Helmholtz Gemeinschaft | Chimeric antigen receptor and car-t cells that bind bcma |
| CN107827989A (zh) * | 2017-10-18 | 2018-03-23 | 银丰生物工程集团有限公司 | 靶向骨髓瘤bcma抗原的转基因t细胞及其制备方法与应用 |
| CN116836297A (zh) | 2018-04-12 | 2023-10-03 | 上海赛比曼生物科技有限公司 | 靶向bcma的嵌合抗原受体及其制法和应用 |
-
2018
- 2018-04-12 CN CN202310450645.4A patent/CN116836297A/zh active Pending
- 2018-04-12 CN CN201810326346.9A patent/CN110372796B/zh active Active
- 2018-04-12 CN CN202310447932.XA patent/CN116514995A/zh active Pending
-
2019
- 2019-04-02 WO PCT/CN2019/081064 patent/WO2019196713A1/zh not_active Ceased
- 2019-04-02 KR KR1020207032269A patent/KR20200142036A/ko active Pending
- 2019-04-02 JP JP2020531444A patent/JP7148611B2/ja active Active
- 2019-04-02 SG SG11202009962UA patent/SG11202009962UA/en unknown
- 2019-04-02 EP EP19784803.9A patent/EP3778651A4/en active Pending
- 2019-04-02 AU AU2019251016A patent/AU2019251016B2/en active Active
- 2019-04-02 CA CA3095827A patent/CA3095827A1/en active Pending
-
2020
- 2020-05-22 US US16/881,668 patent/US11142581B2/en active Active
-
2021
- 2021-09-16 US US17/476,661 patent/US11498973B2/en active Active
- 2021-11-24 JP JP2021190474A patent/JP7299294B2/ja active Active
-
2022
- 2022-09-23 US US17/951,774 patent/US20230053305A1/en active Pending
-
2023
- 2023-06-15 JP JP2023098770A patent/JP2023116716A/ja active Pending
- 2023-06-29 AU AU2023204159A patent/AU2023204159B2/en active Active
-
2025
- 2025-03-26 JP JP2025051295A patent/JP2025098166A/ja active Pending
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