|
CA136551A
(en)
|
1911-08-03 |
1911-10-31 |
Hedwig Heeron |
Rolling mill
|
|
US4690915A
(en)
|
1985-08-08 |
1987-09-01 |
The United States Of America As Represented By The Department Of Health And Human Services |
Adoptive immunotherapy as a treatment modality in humans
|
|
IE20030749A1
(en)
|
1991-05-03 |
2003-11-12 |
Indiana University Foundation |
Human notch and delta binding domains in torporythmic proteins, and methods based thereon
|
|
US5420032A
(en)
|
1991-12-23 |
1995-05-30 |
Universitge Laval |
Homing endonuclease which originates from chlamydomonas eugametos and recognizes and cleaves a 15, 17 or 19 degenerate double stranded nucleotide sequence
|
|
US5792632A
(en)
|
1992-05-05 |
1998-08-11 |
Institut Pasteur |
Nucleotide sequence encoding the enzyme I-SceI and the uses thereof
|
|
US5780300A
(en)
|
1995-09-29 |
1998-07-14 |
Yale University |
Manipulation of non-terminally differentiated cells using the notch pathway
|
|
WO1997034634A1
(en)
|
1996-03-20 |
1997-09-25 |
Sloan-Kettering Institute For Cancer Research |
Single chain fv constructs of anti-ganglioside gd2 antibodies
|
|
EP0942998B1
(en)
*
|
1996-11-07 |
2005-07-06 |
Lorantis Limited |
Notch
|
|
WO2000014257A1
(en)
|
1998-09-04 |
2000-03-16 |
Sloan-Kettering Institute For Cancer Research |
Fusion receptors specific for prostate-specific membrane antigen and uses thereof
|
|
CA2410510A1
(en)
|
2000-06-02 |
2001-12-13 |
Memorial Sloan-Kettering Cancer Center |
Artificial antigen presenting cells and methods of use thereof
|
|
US6984522B2
(en)
|
2000-08-03 |
2006-01-10 |
Regents Of The University Of Michigan |
Isolation and use of solid tumor stem cells
|
|
US6689744B2
(en)
|
2000-09-22 |
2004-02-10 |
Genentech, Inc. |
Notch receptor agonists and uses
|
|
US20030119771A1
(en)
|
2001-08-22 |
2003-06-26 |
Rompaey Luc Van |
Modulators of bone homeostasis identified in a high-throughput screen
|
|
JP2003093048A
(ja)
*
|
2001-09-26 |
2003-04-02 |
Asahi Kasei Corp |
新規細胞製剤製造用培養媒体
|
|
US20030170238A1
(en)
|
2002-03-07 |
2003-09-11 |
Gruenberg Micheal L. |
Re-activated T-cells for adoptive immunotherapy
|
|
AU2003215869B2
(en)
|
2002-03-15 |
2008-04-24 |
Cellectis |
Hybrid and single chain meganucleases and use thereof
|
|
EP1492816A2
(en)
*
|
2002-04-05 |
2005-01-05 |
Lorantis Limited |
Modulators of the notch signalling pathway and uses thereof in medical treatment
|
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
|
AU2003269268A1
(en)
*
|
2002-10-09 |
2004-05-04 |
Lorantis Limited |
Modulation of immune function
|
|
WO2004064863A1
(en)
*
|
2003-01-23 |
2004-08-05 |
Lorantis Limited |
Treatment of autoimmune diseases using an activator for the notch signaling pathway
|
|
AU2004208031B2
(en)
|
2003-01-28 |
2009-10-08 |
Cellectis |
Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof.
|
|
CA2589279A1
(en)
*
|
2004-11-24 |
2006-06-01 |
Val-Chum, S.E.C. |
Methods to identify, prepare, and use naive t cell recent thymic emigrants
|
|
WO2007027226A2
(en)
*
|
2005-04-28 |
2007-03-08 |
Board Of Regents, The University Of Texas System |
Systems and methods for the production of differentiated cells
|
|
EP2650366B1
(en)
|
2005-10-18 |
2017-03-22 |
Precision Biosciences |
Rationally designed meganucleases with altered sequence specificity and DNA-binding affinity
|
|
CL2007002987A1
(es)
|
2006-10-19 |
2008-06-06 |
Genentech Inc |
Anticuerpos anti-notch3; acido nucleico que los codifica; vector y celula que lo comprende; metodo de produccion; y su uso para tratar enfermedades relacionadas con notch3.
|
|
UA102061C2
(ru)
|
2006-10-19 |
2013-06-10 |
Дженентек, Інк. |
Агонистическое антитело к notch3 и его применение для лечения notch3- ассоциированных заболеваний
|
|
WO2008092445A2
(de)
*
|
2007-01-30 |
2008-08-07 |
Deutsches Rheuma-Forschungszentrum Berlin |
Verfahren zur modulation der immunantwort durch aktivierung oder inaktivierung des notch und/oder stat4 signalweges
|
|
PL2856876T3
(pl)
|
2007-03-30 |
2018-06-29 |
Memorial Sloan-Kettering Cancer Center |
Konstytutywna ekspresja ligandów kostymulujących na limfocytach T poddanych transferowi adoptywnemu
|
|
WO2010054007A1
(en)
|
2008-11-07 |
2010-05-14 |
Fabrus Llc |
Combinatorial antibody libraries and uses thereof
|
|
WO2010059543A1
(en)
|
2008-11-20 |
2010-05-27 |
Merck Sharp & Dohme Corp. |
Generation and characterization of anti-notch antibodies for therapeutic and diagnostic use
|
|
WO2010141249A2
(en)
|
2009-06-02 |
2010-12-09 |
Merck Sharp & Dohme Corp. |
Generation, characterization and uses thereof of anti-notch3 antibodies
|
|
EP3156062A1
(en)
|
2010-05-17 |
2017-04-19 |
Sangamo BioSciences, Inc. |
Novel dna-binding proteins and uses thereof
|
|
PH12013501201A1
(en)
|
2010-12-09 |
2013-07-29 |
Univ Pennsylvania |
Use of chimeric antigen receptor-modified t cells to treat cancer
|
|
WO2013126726A1
(en)
|
2012-02-22 |
2013-08-29 |
The Trustees Of The University Of Pennsylvania |
Double transgenic t cells comprising a car and a tcr and their methods of use
|
|
LT3401400T
(lt)
|
2012-05-25 |
2019-06-10 |
The Regents Of The University Of California |
Būdai ir kompozicijos, skirtos rnr molekulės nukreipiamai tikslinės dnr modifikacijai ir rnr molekulės nukreipiamam transkripcijos moduliavimui
|
|
WO2014039044A1
(en)
*
|
2012-09-06 |
2014-03-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Methods of producing t memory stem cell populations
|
|
EP2896697B1
(en)
|
2012-12-12 |
2015-09-02 |
The Broad Institute, Inc. |
Engineering of systems, methods and optimized guide compositions for sequence manipulation
|
|
US8697359B1
(en)
|
2012-12-12 |
2014-04-15 |
The Broad Institute, Inc. |
CRISPR-Cas systems and methods for altering expression of gene products
|
|
US10696946B2
(en)
*
|
2013-02-22 |
2020-06-30 |
The Board Of Trustees Of The University Of Illinois |
T-REG cell expansion
|
|
US9683039B2
(en)
|
2013-03-14 |
2017-06-20 |
New York University |
Notch agonists for the treatment of cancer
|
|
CA2930877A1
(en)
|
2013-11-18 |
2015-05-21 |
Crispr Therapeutics Ag |
Crispr-cas system materials and methods
|
|
CA2948871A1
(en)
|
2014-05-22 |
2015-11-26 |
Fred Hutchinson Cancer Research Center |
Lilrb2 and notch-mediated expansion of hematopoietic precursor cells
|
|
JP6641299B2
(ja)
|
2014-06-04 |
2020-02-05 |
フレッド ハッチンソン キャンサー リサーチ センター |
Notch 1および/またはNotch 2アゴニストを用いた幹細胞の増殖および生着
|
|
MX389823B
(es)
*
|
2014-10-27 |
2025-03-20 |
Fred Hutchinson Cancer Center |
Composiciones y metodos para reforzar la eficacia de inmunoterapia celular adoptiva.
|
|
ES2862676T3
(es)
*
|
2015-10-20 |
2021-10-07 |
Fujifilm Cellular Dynamics Inc |
Producción de células precursoras hematopoyéticas multilinaje mediante programación genética
|
|
US11466253B2
(en)
*
|
2015-10-22 |
2022-10-11 |
Juno Therapeutics Gmbh |
Methods for culturing cells and kits and apparatus for same
|
|
MX2018005274A
(es)
*
|
2015-10-30 |
2019-09-19 |
The Regents Of The Universtiy Of California |
Metodos para la generacion de celulas-t a partir de celulas madre y metodos inmunoterapeuticos que utilizan las celulas-t.
|
|
US12076342B2
(en)
*
|
2016-04-08 |
2024-09-03 |
The Governing Council Of The University Of Toronto |
Method for generating progenitor t cells from stem and/or progenitor cells and use of same
|
|
US11261250B2
(en)
|
2016-07-22 |
2022-03-01 |
Fred Hutchinson Cancer Research Center |
Bi-specific molecule for cell-specific Notch inhibition and related methods and compositions
|