JP2021533806A5 - - Google Patents

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Publication number
JP2021533806A5
JP2021533806A5 JP2021510030A JP2021510030A JP2021533806A5 JP 2021533806 A5 JP2021533806 A5 JP 2021533806A5 JP 2021510030 A JP2021510030 A JP 2021510030A JP 2021510030 A JP2021510030 A JP 2021510030A JP 2021533806 A5 JP2021533806 A5 JP 2021533806A5
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JP
Japan
Prior art keywords
seq
amino acid
antigen
acid sequence
binding
Prior art date
Application number
JP2021510030A
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English (en)
Japanese (ja)
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JP2021533806A (ja
JPWO2020041537A5 (https=
JP7402223B2 (ja
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Priority claimed from PCT/US2019/047601 external-priority patent/WO2020041537A1/en
Publication of JP2021533806A publication Critical patent/JP2021533806A/ja
Publication of JP2021533806A5 publication Critical patent/JP2021533806A5/ja
Publication of JPWO2020041537A5 publication Critical patent/JPWO2020041537A5/ja
Priority to JP2023172194A priority Critical patent/JP7541167B2/ja
Application granted granted Critical
Publication of JP7402223B2 publication Critical patent/JP7402223B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021510030A 2018-08-23 2019-08-22 抗fcイプシロン-r1アルファ(fcer1a)抗体、fcer1aおよびcd3に結合する二重特異性抗原結合分子、ならびにそれらの使用 Active JP7402223B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023172194A JP7541167B2 (ja) 2018-08-23 2023-10-03 抗fcイプシロン-r1アルファ(fcer1a)抗体、fcer1aおよびcd3に結合する二重特異性抗原結合分子、ならびにそれらの使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862721921P 2018-08-23 2018-08-23
US62/721,921 2018-08-23
PCT/US2019/047601 WO2020041537A1 (en) 2018-08-23 2019-08-22 Anti-fc epsilon-r1 alpha (fcer1a) antibodies, bispecific antigen-binding molecules that bind fcer1a and cd3, and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023172194A Division JP7541167B2 (ja) 2018-08-23 2023-10-03 抗fcイプシロン-r1アルファ(fcer1a)抗体、fcer1aおよびcd3に結合する二重特異性抗原結合分子、ならびにそれらの使用

Publications (4)

Publication Number Publication Date
JP2021533806A JP2021533806A (ja) 2021-12-09
JP2021533806A5 true JP2021533806A5 (https=) 2022-08-04
JPWO2020041537A5 JPWO2020041537A5 (https=) 2022-08-04
JP7402223B2 JP7402223B2 (ja) 2023-12-20

Family

ID=67876086

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021510030A Active JP7402223B2 (ja) 2018-08-23 2019-08-22 抗fcイプシロン-r1アルファ(fcer1a)抗体、fcer1aおよびcd3に結合する二重特異性抗原結合分子、ならびにそれらの使用
JP2023172194A Active JP7541167B2 (ja) 2018-08-23 2023-10-03 抗fcイプシロン-r1アルファ(fcer1a)抗体、fcer1aおよびcd3に結合する二重特異性抗原結合分子、ならびにそれらの使用

Family Applications After (1)

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JP2023172194A Active JP7541167B2 (ja) 2018-08-23 2023-10-03 抗fcイプシロン-r1アルファ(fcer1a)抗体、fcer1aおよびcd3に結合する二重特異性抗原結合分子、ならびにそれらの使用

Country Status (18)

Country Link
US (2) US11578127B2 (https=)
EP (1) EP3840841A1 (https=)
JP (2) JP7402223B2 (https=)
KR (1) KR20210049863A (https=)
CN (1) CN112888482B (https=)
AU (1) AU2019325565B2 (https=)
BR (1) BR112021003023A2 (https=)
CA (1) CA3109513A1 (https=)
CL (2) CL2021000437A1 (https=)
CO (1) CO2021003608A2 (https=)
EA (1) EA202190601A1 (https=)
IL (1) IL280745B1 (https=)
MX (1) MX2021002165A (https=)
MY (1) MY204368A (https=)
PH (1) PH12021550322A1 (https=)
SG (1) SG11202101608XA (https=)
WO (1) WO2020041537A1 (https=)
ZA (1) ZA202100919B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3840841A1 (en) 2018-08-23 2021-06-30 Regeneron Pharmaceuticals, Inc. Anti-fc epsilon-r1 alpha (fcer1a) antibodies, bispecific antigen-binding molecules that bind fcer1a and cd3, and uses thereof
WO2021159128A2 (en) * 2020-01-31 2021-08-12 Randy Leiman Allen Methods and kit for detection of analytes
WO2025149667A1 (en) 2024-01-12 2025-07-17 Pheon Therapeutics Ltd Antibody drug conjugates and uses thereof

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IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
WO2006028956A2 (en) * 2004-09-02 2006-03-16 Genentech, Inc. Anti-fc-gamma riib receptor antibody and uses therefor
ES2398076T3 (es) 2006-06-02 2013-03-13 Regeneron Pharmaceuticals, Inc. Anticuerpos de alta afinidad contra el receptor de IL-6 humano
JP5816170B2 (ja) 2009-06-26 2015-11-18 リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. 天然の免疫グロブリン形式を有する容易に単離される二重特異性抗体
SI2501817T2 (sl) 2010-02-08 2021-09-30 Regeneron Pharmaceuticals, Inc. Miš z navadno lahko verigo
US9868786B2 (en) * 2011-04-12 2018-01-16 University Of Cincinnati Methods for suppressing allergic reactions
WO2012169741A2 (ko) 2011-06-07 2012-12-13 (주)네오팜 FcεRI 특이적 인간 항체 및 이를 포함하는 알레르기 질환 치료 또는 진단용 조성물
JOP20200236A1 (ar) 2012-09-21 2017-06-16 Regeneron Pharma الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
TWI682941B (zh) 2013-02-01 2020-01-21 美商再生元醫藥公司 含嵌合恆定區之抗體
EP2837637A1 (en) 2013-08-16 2015-02-18 SuppreMol GmbH Novel anti-FcyRIIB IgG-type antibody
CN104293738A (zh) 2013-09-11 2015-01-21 李莉 一种抗人FcεRⅠα亚基单克隆抗体及其应用
EP2982693A1 (en) * 2014-08-07 2016-02-10 Affimed Therapeutics AG CD3 binding domain
CA2957850A1 (en) 2014-08-13 2016-02-18 Suppremol Gmbh Antibodies comprising binding domains to fc.epsilon. receptor (fc.epsilon.r) and fc gamma receptor iib (fc.gamma.riib)
CN104800164B (zh) 2015-04-13 2017-11-07 上海市第一人民医院 一种雷公藤免疫纳米粒及用途
LT3353212T (lt) 2015-09-23 2021-12-27 Regeneron Pharmaceuticals, Inc. Optimizuoti anti-cd3 bispecifiniai antikūnai ir jų naudojimas
IL262241B2 (en) * 2016-04-13 2024-05-01 Sanofi Sa Trispecific and/or trivalent binding proteins with a crossover dual variable domain arm and a traditional antibody fab arm, pharmaceutical composition comprising said binding proteins and their uses in preventing and/or treating cancer or inflammatory diseases
MY194596A (en) 2016-09-23 2022-12-06 Regeneron Pharma Bi Specific Anti-Muc16-CD3 Antibodies And Anti-Muc16 Drug Conjugates
EP3840841A1 (en) 2018-08-23 2021-06-30 Regeneron Pharmaceuticals, Inc. Anti-fc epsilon-r1 alpha (fcer1a) antibodies, bispecific antigen-binding molecules that bind fcer1a and cd3, and uses thereof

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