JP2021533771A - 核酸のインビトロ検出 - Google Patents

核酸のインビトロ検出 Download PDF

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Publication number
JP2021533771A
JP2021533771A JP2021507661A JP2021507661A JP2021533771A JP 2021533771 A JP2021533771 A JP 2021533771A JP 2021507661 A JP2021507661 A JP 2021507661A JP 2021507661 A JP2021507661 A JP 2021507661A JP 2021533771 A JP2021533771 A JP 2021533771A
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nucleic acid
sensor system
sensor
hybridization region
hybridization
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JP2021533771A5 (enExample
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ウィリアム ジェレミー ブレイク
サード カール ダブリュ． ブラウン
フレデリク ヴィニョー
ジェームズ ジェイ． コリンズ
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Massachusetts Institute of Technology
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
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    • C12Q1/6813—Hybridisation assays
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    • C12Q1/6825—Nucleic acid detection involving sensors
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
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    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

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JP2021507661A 2018-08-14 2019-08-14 核酸のインビトロ検出 Pending JP2021533771A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862718427P 2018-08-14 2018-08-14
US62/718,427 2018-08-14
PCT/US2019/046497 WO2020037038A1 (en) 2018-08-14 2019-08-14 In vitro detection of nucleic acid

Publications (2)

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JP2021533771A true JP2021533771A (ja) 2021-12-09
JP2021533771A5 JP2021533771A5 (enExample) 2022-08-19

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JP2021507661A Pending JP2021533771A (ja) 2018-08-14 2019-08-14 核酸のインビトロ検出

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US (1) US12644148B2 (enExample)
EP (1) EP3837362A4 (enExample)
JP (1) JP2021533771A (enExample)
KR (1) KR20210043605A (enExample)
CN (1) CN112840022A (enExample)
AU (1) AU2019321447A1 (enExample)
BR (1) BR112021002609A2 (enExample)
CA (1) CA3109392A1 (enExample)
IL (1) IL280603A (enExample)
MX (1) MX2021001685A (enExample)
SG (1) SG11202101405RA (enExample)
WO (1) WO2020037038A1 (enExample)

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EP4200438A1 (en) * 2020-08-18 2023-06-28 Sherlock Biosciences, Inc. Hybridisation-based sensor systems and probes
WO2022046979A1 (en) * 2020-08-26 2022-03-03 Arizona Board Of Regents On Behalf Of Arizona State University Rapid and low-cost nucleic acid detection using translation-based sequence verification assays
WO2023283622A1 (en) 2021-07-08 2023-01-12 Montana State University Crispr-based programmable rna editing
US11814689B2 (en) 2021-07-21 2023-11-14 Montana State University Nucleic acid detection using type III CRISPR complex
KR102818567B1 (ko) * 2022-05-31 2025-06-11 충남대학교 산학협력단 타겟 핵산 검출용 조성물 및 이의 용도
EP4547865A1 (en) 2022-07-01 2025-05-07 Sherlock Biosciences, Inc. Ambient temperature nucleic acid amplification and detection
CN117330755B (zh) * 2023-08-25 2024-03-26 广东省农业科学院农业生物基因研究中心 一种基于酶催化生物荧光定量检测dna-蛋白质相互作用的方法
KR20250074706A (ko) * 2023-11-15 2025-05-28 대한민국(방위사업청장) 무세포 단백질 합성과 재귀반사신호에 기반한 표적물질 검출방법
KR20250085854A (ko) * 2023-12-04 2025-06-13 충남대학교산학협력단 타겟 핵산 검출용 조성물 및 이의 용도
WO2026015653A2 (en) 2024-07-09 2026-01-15 Sherlock Biosciences, Inc. Power-free fluidic device
WO2026104594A1 (en) * 2024-11-15 2026-05-21 Eth Zurich Biosensor

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WO2017191007A1 (en) * 2016-05-04 2017-11-09 General Electric Company Cell-free protein expression using rolling circle amplification product

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AU2019321447A1 (en) 2021-02-25
CA3109392A1 (en) 2020-02-20
CN112840022A (zh) 2021-05-25
IL280603A (en) 2021-03-25
KR20210043605A (ko) 2021-04-21
MX2021001685A (es) 2021-05-27
EP3837362A1 (en) 2021-06-23
WO2020037038A1 (en) 2020-02-20
US20210164025A1 (en) 2021-06-03
US12644148B2 (en) 2026-06-02
BR112021002609A2 (pt) 2021-05-11
SG11202101405RA (en) 2021-03-30
EP3837362A4 (en) 2022-05-11

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