JP2021533134A5 - - Google Patents

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Publication number
JP2021533134A5
JP2021533134A5 JP2021505847A JP2021505847A JP2021533134A5 JP 2021533134 A5 JP2021533134 A5 JP 2021533134A5 JP 2021505847 A JP2021505847 A JP 2021505847A JP 2021505847 A JP2021505847 A JP 2021505847A JP 2021533134 A5 JP2021533134 A5 JP 2021533134A5
Authority
JP
Japan
Prior art keywords
conhch
och
group
cells
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021505847A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021533134A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/044421 external-priority patent/WO2020028532A1/en
Publication of JP2021533134A publication Critical patent/JP2021533134A/ja
Publication of JP2021533134A5 publication Critical patent/JP2021533134A5/ja
Pending legal-status Critical Current

Links

JP2021505847A 2018-08-02 2019-07-31 チェックポイント阻害抗体と相乗効果を示し、疾患を排除するtlr1/2アゴニストジプロボッシムのアジュバント効果 Pending JP2021533134A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862713823P 2018-08-02 2018-08-02
US62/713,823 2018-08-02
PCT/US2019/044421 WO2020028532A1 (en) 2018-08-02 2019-07-31 Adjuvant effect of the tlr1/2 agonist diprovocim synergizes with checkpoint-inhibiting antibodies to eliminate disease

Publications (2)

Publication Number Publication Date
JP2021533134A JP2021533134A (ja) 2021-12-02
JP2021533134A5 true JP2021533134A5 (enExample) 2022-09-22

Family

ID=69232110

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021505847A Pending JP2021533134A (ja) 2018-08-02 2019-07-31 チェックポイント阻害抗体と相乗効果を示し、疾患を排除するtlr1/2アゴニストジプロボッシムのアジュバント効果

Country Status (10)

Country Link
US (1) US20210315992A1 (enExample)
EP (1) EP3829571B1 (enExample)
JP (1) JP2021533134A (enExample)
KR (1) KR20210029280A (enExample)
CN (1) CN113164445A (enExample)
AU (2) AU2019315952A1 (enExample)
BR (1) BR112021001992A2 (enExample)
CA (1) CA3108515A1 (enExample)
IL (1) IL280584B2 (enExample)
WO (1) WO2020028532A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11938182B2 (en) 2020-03-26 2024-03-26 Provectus Pharmatech, Inc. Halogenated xanthenes as vaccine adjuvants
EP4103283A4 (en) 2020-03-26 2024-02-28 Provectus Pharmatech, Inc. NEW USES OF HALOGENATED XANTHENES IN ONCOLOGY AND VIROLOGY
CN115666553A (zh) * 2020-05-27 2023-01-31 轴向治疗公司 Tlr2调节剂化合物及其药物组合物和用途
US20230210925A1 (en) * 2020-07-14 2023-07-06 Dic Corporation Composition for cytotoxic t lymphocyte (ctl) activation
WO2023212650A1 (en) * 2022-04-29 2023-11-02 The Scripps Research Institute Next generation diprovocims that activate the innate and adaptive immune response

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4599231A (en) 1984-03-09 1986-07-08 Scripps Clinic And Research Foundation Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US5180806A (en) 1988-05-16 1993-01-19 The Scripps Research Institute Polypeptides and compositions of human papillomavirus latent proteins, diagnostic systems and methods
US6489354B1 (en) 1999-03-02 2002-12-03 Merck & Co., Inc. 3-alkyl substituted pyrrolidine modulators of chemokine receptor activity
US6942866B2 (en) 2000-08-16 2005-09-13 Apovia, Inc. Malaria immunogen and vaccine
ATE361068T1 (de) * 2001-08-08 2007-05-15 Pentraxin Therapeutics Ltd Wirkstoff zur entfernung einer unerwünschten proteinpopulation aus dem plasma
US7361352B2 (en) 2001-08-15 2008-04-22 Acambis, Inc. Influenza immunogen and vaccine
US20090081157A1 (en) * 2006-01-09 2009-03-26 Richard Syd Kornbluth Immunostimulatory Combinations for Vaccine Adjuvants
CA2899577C (en) * 2013-04-03 2023-10-17 Ibc Pharmaceuticals, Inc. Combination therapy for inducing immune response to disease
EP3177601B1 (en) * 2014-08-06 2023-03-01 The Scripps Research Institute Tlr-independent small molecule adjuvants
CN107427567A (zh) * 2015-01-29 2017-12-01 宾夕法尼亚大学理事会 检查点抑制剂和疫苗组合物及其用于免疫疗法的用途
MX2017012939A (es) * 2015-04-08 2018-05-22 Novartis Ag Terapias cd20, terapias cd22 y terapias de combinacion con una celula que expresa un receptor quimerico de antigeno (car) de cd19.
CR20180519A (es) * 2016-03-31 2019-03-05 Neon Therapeutics Inc Neoantígenos y métodos de su uso
JP6964298B2 (ja) * 2016-06-29 2021-11-10 ザ スクリプス リサーチ インスティテュート ジプロボシム:新規かつ強力なクラスのtlrアゴニスト
US20180088749A1 (en) 2016-09-26 2018-03-29 Uber Technologies, Inc. Customized content generation for a user interface for a network service
US20180169224A1 (en) * 2016-12-12 2018-06-21 Wisconsin Alumni Research Foundation Tlr agonists for reducing activation-induced pd-1 expression on t cells and methods of use

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