JP2021531281A5 - - Google Patents

Info

Publication number
JP2021531281A5
JP2021531281A5 JP2021502765A JP2021502765A JP2021531281A5 JP 2021531281 A5 JP2021531281 A5 JP 2021531281A5 JP 2021502765 A JP2021502765 A JP 2021502765A JP 2021502765 A JP2021502765 A JP 2021502765A JP 2021531281 A5 JP2021531281 A5 JP 2021531281A5
Authority
JP
Japan
Prior art keywords
stem cells
pharmaceutical composition
human
cells
composition according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021502765A
Other languages
English (en)
Japanese (ja)
Other versions
JP7586811B2 (ja
JP2021531281A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IL2019/050821 external-priority patent/WO2020021534A1/en
Publication of JP2021531281A publication Critical patent/JP2021531281A/ja
Publication of JP2021531281A5 publication Critical patent/JP2021531281A5/ja
Application granted granted Critical
Publication of JP7586811B2 publication Critical patent/JP7586811B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021502765A 2018-07-22 2019-07-22 腎臓疾患のミトコンドリア増強療法 Active JP7586811B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862701783P 2018-07-22 2018-07-22
US62/701,783 2018-07-22
US201862753934P 2018-11-01 2018-11-01
US62/753,934 2018-11-01
PCT/IL2019/050821 WO2020021534A1 (en) 2018-07-22 2019-07-22 Mitochondrial augmentation therapy of renal diseases

Publications (3)

Publication Number Publication Date
JP2021531281A JP2021531281A (ja) 2021-11-18
JP2021531281A5 true JP2021531281A5 (enExample) 2022-07-27
JP7586811B2 JP7586811B2 (ja) 2024-11-19

Family

ID=69180899

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021502765A Active JP7586811B2 (ja) 2018-07-22 2019-07-22 腎臓疾患のミトコンドリア増強療法

Country Status (5)

Country Link
US (1) US12329781B2 (enExample)
EP (1) EP3823645B1 (enExample)
JP (1) JP7586811B2 (enExample)
ES (1) ES2992862T3 (enExample)
WO (1) WO2020021534A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI857807B (zh) * 2020-03-20 2024-10-01 台灣粒線體應用技術股份有限公司 含有粒線體之組合物及其用於作為皮膚纖維母細胞活性促進劑之用途
US20240082183A1 (en) * 2021-01-07 2024-03-14 The Regents Of The University Of Michigan Methods for preventing or treating conditions related to t cell mediated intestinal disorders
CA3239683A1 (en) * 2021-12-13 2023-06-22 Natalie YIVGI-OHANA Mitochondrial augmentation therapy for myelodysplastic syndrome

Family Cites Families (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2186636A1 (en) 1994-03-30 1995-10-12 Corinna Herrnstadt Diagnosis, therapy and cellular and animal models for diseases associated with mitochondrial defects
US6472378B2 (en) 1998-08-31 2002-10-29 Pro-Neuron, Inc. Compositions and methods for treatment of mitochondrial diseases
EP1119368A2 (en) 1999-03-03 2001-08-01 Biogen, Inc. Methods of modulating lipid metabolism and storage
GB2350565A (en) 1999-05-28 2000-12-06 Johnson & Johnson Medical Ltd Biological wound dressings comprising mitochondria
DE19937348A1 (de) 1999-08-11 2001-02-22 Aventis Cropscience Gmbh Nukleinsäuremoleküle aus Pflanzen codierend Enzyme, die an der Stärkesynthese beteiligt sind
EP1267800A4 (en) 2000-03-31 2004-08-25 Gen Hospital Corp METHOD FOR INFLUENCING HAIR GROWTH
WO2002030418A1 (fr) 2000-10-13 2002-04-18 Chugai Seiyaku Kabushiki Kaisha Compositions servant a ameliorer le metabolisme lipidique
US20030040475A1 (en) 2001-01-16 2003-02-27 Yasuhiro Toba Agents for improving lipid metabolism and reducing high blood pressure
US7339090B2 (en) 2001-02-13 2008-03-04 Avigenics, Inc. Microinjection devices and methods of use
JP4603192B2 (ja) 2001-05-10 2010-12-22 株式会社カネカ 毛髪頭皮用組成物
AU2002330938A1 (en) 2001-07-31 2003-02-17 Northeastern University Mitochondrial genome replenishment
EP1423504B1 (en) 2001-08-08 2009-09-23 Levesque Biosciences, Inc. Compositions and methods for isolation, propagation, and differentiation of non-embryonic human stem cells and uses thereof
US7138134B2 (en) 2001-12-18 2006-11-21 Arizona Health Consulting Group, Llc Preparation and administration of jojoba product for reducing weight, fat and blood lipid levels
US20050153381A1 (en) 2002-02-14 2005-07-14 Marusich Michael F. Immunocapture of mitochondrial protein complexes
CA2525560A1 (en) 2003-05-13 2004-11-25 The Regents Of The University Of Colorado Diagnostic and therapeutic treatments related to mitochondrial disorders
EP1626732B1 (en) 2003-05-22 2013-04-03 CHIESI FARMACEUTICI S.p.A. Means for preventing and treating cellular death and their biological applications
US7407800B1 (en) 2003-09-19 2008-08-05 Pierce Biotechnology, Inc. Method for the isolation of intact mitochondria from cells
EP1709084A4 (en) 2003-12-23 2008-05-28 Nono Inc POLYPEPTIDES FOR MODULATING BINDING OF TRP-CHANNEL PROTEINS AND TRP-ASSOCIATED PROTEINS
US20060024277A1 (en) 2004-07-27 2006-02-02 Sivak Hannah N Method of skin care and/or treatment using extracts enriched in mitochondria
JP2006131600A (ja) 2004-11-09 2006-05-25 R & D Cell-Science Optional Medico:Kk 発毛促進のためのヒト細胞組成物
CA2609208C (en) 2005-06-10 2016-10-18 Per-Ake Albertsson Use of plant cell membrane for the treatment of obesity
AU2012201710B2 (en) 2006-05-11 2014-01-16 Regenics As Administration of cells and cellular extracts for rejuvenation
AT502353B1 (de) 2006-06-29 2007-07-15 Avl List Gmbh Verfahren und vorrichtung zur konditionierung eines o2-hältigen gases
US9603872B2 (en) 2007-05-02 2017-03-28 The McLeon Hospital Corporation Methods and compositions for mitochondrial replacement therapy
WO2008152640A2 (en) 2007-06-13 2008-12-18 Pluristem Ltd. Three dimensional biocompatible scaffolds for ex-vivo expansion and transplantation of stem cells
JP5866601B2 (ja) 2008-06-18 2016-02-17 ザ テキサス エーアンドエム ユニバーシティ システムThe Texas A&M University System 医薬組成物の製造方法
KR20120100962A (ko) * 2009-10-02 2012-09-12 박스터 헬쓰케어 에스.에이. 신장 손상을 치료하는데 사용하기 위한 조혈 줄기 세포
WO2011059547A2 (en) 2009-10-30 2011-05-19 Xenotech, Llc Cryopreservation of cells and subcellular fractions
US8846028B2 (en) 2010-10-28 2014-09-30 The Invention Science Fund I, Llc Mitochondrial enhancement of cells
US8883838B2 (en) 2010-12-03 2014-11-11 Allergan, Inc. Pharmaceutical cream compositions and methods of use
PH12022550598A1 (en) 2010-12-23 2024-03-11 Amazentis Sa Compositions and methods for improving mitochondrial function and treating neurodenegenerative diseases and cognitive disorders
EA201490050A1 (ru) 2011-06-29 2014-07-30 Зе Дженерэл Хоспитэл Корпорейшн Композиции и способы повышения биоэнергетического состояния женских зародышевых клеток
CN102266350A (zh) 2011-07-20 2011-12-07 黄必录 逆转干细胞衰老的方案
US20130022666A1 (en) 2011-07-20 2013-01-24 Anna Brzezinska Methods and compositions for transfer of mitochondria into mammalian cells
CN102293178A (zh) 2011-08-28 2011-12-28 黄必录 使个体去衰老的方法
IL282198B2 (en) 2011-09-11 2025-11-01 Minovia Therapeutics Ltd Compositions of functional mitochondria and uses thereof
JP6220791B2 (ja) 2011-12-02 2017-10-25 フェイト セラピューティクス,インコーポレイテッド 増強された幹細胞組成物
US8648034B2 (en) 2011-12-09 2014-02-11 Changhua Christian Hospital Method and applications of peptide-mediated mitochondrial delivery system
WO2013149064A1 (en) 2012-03-30 2013-10-03 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Uridine diphosphate compounds as mobilizers of hematopoietic progenitor cells
WO2013171752A1 (en) 2012-05-16 2013-11-21 Minovia Therapeutics Ltd. Compositions and methods for inducing angiogenesis
EP3459522B1 (en) 2012-12-10 2021-02-17 Regenics AS Use of egg cellular extracts for wound treatment
AU2014219026B2 (en) 2013-02-19 2018-11-29 Children's Medical Center Corporation ABCB5(+) stem cells for treating ocular disease
DE102013225588A1 (de) 2013-12-11 2014-04-17 Henkel Ag & Co. Kgaa Verwendung und Mittel zur Verbesserung der Haarstruktur
AU2015214145A1 (en) 2014-02-04 2016-08-25 Kite Pharma. Inc. Methods for producing autologous T cells useful to treat B cell malignancies and other cancers and compositions thereof
EP2918458B1 (en) 2014-03-11 2016-12-07 Autoliv Development AB A vehicle braking arrangement
WO2015142855A1 (en) 2014-03-17 2015-09-24 University Of Virginia Patent Foundation Compositions and methods for treating retinopathy
CN103976935A (zh) 2014-05-28 2014-08-13 广州市白云区天芳化妆品厂 一种抗衰原液及其制备方法
KR20170032406A (ko) 2014-07-15 2017-03-22 주노 쎄러퓨티크스 인코퍼레이티드 입양 세포 치료를 위한 조작된 세포
WO2016008937A1 (en) 2014-07-16 2016-01-21 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the intercellular transfer of isolated mitochondria in recipient cells
TWI707040B (zh) 2014-09-11 2020-10-11 台灣粒線體應用技術股份有限公司 一種用於治療退化性神經疾病的細胞、含有該細胞的醫藥組合物及其應用
JP6441472B2 (ja) 2014-09-30 2018-12-19 台灣粒線體應用技術股▲扮▼有限公司Taiwan Mitochondrion Applied Technology Co.,Ltd. 活性成分として外因性ミトコンドリアを含む組成物、ならびにその使用およびそのための細胞修復法
JP6644702B2 (ja) 2014-11-14 2020-02-12 Jcrファーマ株式会社 歯髄由来多能性幹細胞を含有する筋ジストロフィー治療剤
GB201500427D0 (en) 2015-01-12 2015-02-25 Isis Innovation Method
US20180007913A1 (en) 2015-01-14 2018-01-11 Calix Ltd Improved pathogen inhibitor
IL299482B2 (en) 2015-02-26 2025-02-01 Minovia Therapeutics Ltd Mammalian cells are enriched with active mitochondria
MA41757A (fr) 2015-02-27 2018-01-03 Univ Connecticut Transplantation ciblée de mitochondries dans des hépatocytes
EP3302065A4 (en) 2015-05-28 2019-04-10 Celularity, Inc. PLACENTIAL STEM CELLS FOR RECOVERING THE REGENERATIVE MOTOR, CORRECTING PROTEOMIC DEFECTS AND EXTENDING THE LIFE
US11903974B2 (en) 2015-11-30 2024-02-20 Flagship Pioneering Innovations V, Inc. Methods and compositions relating to chondrisomes from cultured cells
WO2017124037A1 (en) 2016-01-15 2017-07-20 The Children's Medical Center Corporation Therapeutic use of mitochondria and combined mitochondrial agents
KR20190109389A (ko) 2016-11-03 2019-09-25 엑소스템 바이오텍 리미티드 간엽 줄기 세포 집단, 이들의 산물 및 이들의 용도
JP7187036B2 (ja) * 2016-11-14 2022-12-12 パイアン バイオテクノロジ- インコーポレイテッド 外因性ミトコンドリアを細胞内に送達する方法
JP2020502078A (ja) 2016-11-30 2020-01-23 パイアン・バイオテクノロジー・インコーポレイテッドPaean Biotechnology Inc. ミトコンドリアを含む医薬組成物
WO2018178970A1 (en) 2017-03-26 2018-10-04 Minovia Therapeutics Ltd. Mitochondrial compositions and methods for treatment of skin and hair
EP3823644A4 (en) * 2018-07-22 2022-06-08 Minovia Therapeutics Ltd. MITOCHONDRIAL AUGMENTATION THERAPY OF PANCREATIC DISEASES
US11951135B2 (en) * 2018-07-22 2024-04-09 Minovia Therapeutics Ltd. Mitochondrial augmentation therapy of muscle diseases
EP3823646A4 (en) * 2018-07-22 2022-06-08 Minovia Therapeutics Ltd. Mitochondrial augmentation therapy of brain diseases
AU2019311859B2 (en) * 2018-07-22 2025-12-18 Minovia Therapeutics Ltd. Mitochondrial augmentation therapy for primary mitochondrial diseases
EP3823643A4 (en) * 2018-07-22 2022-06-08 Minovia Therapeutics Ltd. MITOCHONDRIAL AUGMENTATION THERAPY OF LIVER DISEASES
WO2020021535A1 (en) 2018-07-22 2020-01-30 Minovia Therapeutics Ltd. Mitochondrial augmentation therapy of ocular diseases
US20210322485A1 (en) * 2018-07-22 2021-10-21 Minovia Therapeutics Ltd. Mitochondrial augmentation therapy with stem cells enriched with functional mitochondria
US20200054682A1 (en) 2018-08-14 2020-02-20 Imel Biotherapeutics, Inc. Methods and compositions for treating mitochondrial disease or disorders and heteroplasmy
CN121610569A (zh) 2019-04-30 2026-03-06 拉利玛生物医药公司 用于测定共济蛋白替代疗法的疗效的共济蛋白敏感性标志物
BR112022019609A2 (pt) 2020-03-31 2022-11-29 Minovia Therapeutics Ltd Células geneticamente modificadas enriquecidas com mitocôndrias e usos das mesmas
AU2021248780A1 (en) 2020-03-31 2022-11-10 Minovia Therapeutics Ltd. Mitochondrial augmentation therapy

Similar Documents

Publication Publication Date Title
JP2021532091A5 (enExample)
Galderisi et al. Clinical trials based on mesenchymal stromal cells are exponentially increasing: where are we in recent years?
Zhidu et al. Translational potential of mesenchymal stem cells in regenerative therapies for human diseases: challenges and opportunities
Li et al. Exosomes derived from mesenchymal stem cells attenuate inflammation and demyelination of the central nervous system in EAE rats by regulating the polarization of microglia
JP2021532094A5 (enExample)
JP2021532095A5 (enExample)
Liang et al. Mesenchymal stem cell transplantation for diffuse alveolar hemorrhage in SLE
Cribbs et al. Stem cells in sepsis and acute lung injury
JP2021532093A5 (enExample)
JP2021531284A5 (enExample)
JP2021531288A5 (enExample)
Yang et al. The therapeutic applications of mesenchymal stromal cells from human perinatal tissues in autoimmune diseases
BRPI0708576A2 (pt) composição compreedendo células-tronco embriÈnicas humanas e seus derivados, métodos de uso e métodos de preparação
KR102097191B1 (ko) 히스톤 탈아세틸화 저해제 및 프라이밍 인자를 유효성분으로 포함하는 줄기세포 활성 촉진용 조성물
JP2022519409A5 (enExample)
JP2009256374A (ja) 疾患および損傷の処置のための一酸化窒素ドナー
Zhou et al. Therapeutic effects of adipose-derived stem cells-based microtissues on erectile dysfunction in streptozotocin-induced diabetic rats
JP2021531281A5 (enExample)
Zhao et al. Novel preconditioning strategies for enhancing the migratory ability of mesenchymal stem cells in acute kidney injury
Tracy et al. State of the field: cellular and exosomal therapeutic approaches in vascular regeneration
Fanos et al. Prolonging nephrogenesis in preterm infants: a new approach for prevention of kidney disease in adulthood?
US20230330146A1 (en) Application of mesenchymal stem cells in preparation of drug for repairing lung damage caused by covid-19
Roch et al. Therapeutic use of adipose-derived stromal cells in a murine model of acute pancreatitis
KR20240099504A (ko) 심부전의 치료 방법
Rajabi et al. Forthcoming complications in recovered COVID-19 patients with COPD and asthma; possible therapeutic opportunities