JP2021530971A5 - - Google Patents

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Publication number
JP2021530971A5
JP2021530971A5 JP2020571816A JP2020571816A JP2021530971A5 JP 2021530971 A5 JP2021530971 A5 JP 2021530971A5 JP 2020571816 A JP2020571816 A JP 2020571816A JP 2020571816 A JP2020571816 A JP 2020571816A JP 2021530971 A5 JP2021530971 A5 JP 2021530971A5
Authority
JP
Japan
Prior art keywords
seq
acid sequence
her2
tac
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020571816A
Other languages
English (en)
Japanese (ja)
Other versions
JP7404279B2 (ja
JP2021530971A (ja
Filing date
Publication date
Priority claimed from US16/442,274 external-priority patent/US10640562B2/en
Application filed filed Critical
Priority claimed from PCT/US2019/042297 external-priority patent/WO2020018727A1/en
Publication of JP2021530971A publication Critical patent/JP2021530971A/ja
Publication of JP2021530971A5 publication Critical patent/JP2021530971A5/ja
Application granted granted Critical
Publication of JP7404279B2 publication Critical patent/JP7404279B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020571816A 2018-07-17 2019-07-17 様々な構築物最適化を備えたt細胞抗原カプラ Active JP7404279B2 (ja)

Applications Claiming Priority (17)

Application Number Priority Date Filing Date Title
US201862699173P 2018-07-17 2018-07-17
US62/699,173 2018-07-17
US201862703037P 2018-07-25 2018-07-25
US62/703,037 2018-07-25
US201862773120P 2018-11-29 2018-11-29
US62/773,120 2018-11-29
US201962826853P 2019-03-29 2019-03-29
US62/826,853 2019-03-29
US201962828879P 2019-04-03 2019-04-03
US62/828,879 2019-04-03
US201962839235P 2019-04-26 2019-04-26
US62/839,235 2019-04-26
US16/442,274 2019-06-14
US16/442,274 US10640562B2 (en) 2018-07-17 2019-06-14 T cell-antigen coupler with various construct optimizations
US201962874426P 2019-07-15 2019-07-15
US62/874,426 2019-07-15
PCT/US2019/042297 WO2020018727A1 (en) 2018-07-17 2019-07-17 T cell-antigen coupler with various construct optimizations

Publications (3)

Publication Number Publication Date
JP2021530971A JP2021530971A (ja) 2021-11-18
JP2021530971A5 true JP2021530971A5 (enExample) 2022-07-14
JP7404279B2 JP7404279B2 (ja) 2023-12-25

Family

ID=69163917

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020571816A Active JP7404279B2 (ja) 2018-07-17 2019-07-17 様々な構築物最適化を備えたt細胞抗原カプラ

Country Status (12)

Country Link
EP (1) EP3823984A4 (enExample)
JP (1) JP7404279B2 (enExample)
KR (1) KR102834084B1 (enExample)
CN (1) CN112689642B (enExample)
AU (1) AU2019307905B2 (enExample)
BR (1) BR112021000735A2 (enExample)
CA (1) CA3104887A1 (enExample)
IL (1) IL280049A (enExample)
MX (1) MX2021000541A (enExample)
PH (1) PH12021550114A1 (enExample)
SG (1) SG11202100307WA (enExample)
WO (1) WO2020018727A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2959480T3 (es) 2014-02-07 2024-02-26 Univ Mcmaster Acoplador de células T - antígeno trifuncional y métodos y usos del mismo
EP3694997A4 (en) 2017-10-12 2021-06-30 Mcmaster University T cell-antigen coupler with y182t mutation and methods and uses thereof
US11110123B2 (en) 2018-07-17 2021-09-07 Triumvira Immunologics Usa, Inc. T cell-antigen coupler with various construct optimizations
US10640562B2 (en) 2018-07-17 2020-05-05 Mcmaster University T cell-antigen coupler with various construct optimizations
EP4326889A2 (en) 2021-04-21 2024-02-28 Conagen Inc. Biosynthetic production of delta-lactones using cytochrome p450 hydroxylase enzymes or mutants thereof
AU2022283819A1 (en) * 2021-06-01 2024-01-04 Triumvira Immunologics Usa, Inc. Claudin 18.2 t cell-antigen couplers and uses thereof
US11453723B1 (en) 2021-06-25 2022-09-27 Mcmaster University BCMA T cell-antigen couplers and uses thereof
CN115820698B (zh) * 2022-11-22 2025-01-21 浙江康佰裕生物科技有限公司 含有嵌合抗原受体和嵌合转换开关受体编码基因的融合基因及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104203981A (zh) * 2011-12-19 2014-12-10 合成免疫股份有限公司 双特异性抗体分子
KR20150029714A (ko) * 2012-07-13 2015-03-18 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 이중특이적 항체의 공-도입에 의한 car 세포의 활성 증강
ES2959480T3 (es) * 2014-02-07 2024-02-26 Univ Mcmaster Acoplador de células T - antígeno trifuncional y métodos y usos del mismo
PL3280729T3 (pl) * 2015-04-08 2022-08-22 Novartis Ag Terapie cd20, terapie cd22 i terapie skojarzone komórką eksprymującą chimeryczny receptor antygenowy (car) cd19
WO2016166139A1 (en) * 2015-04-14 2016-10-20 Eberhard Karls Universität Tübingen Bispecific fusion proteins for enhancing immune responses of lymphocytes against tumor cells
CA3030003A1 (en) * 2016-07-08 2018-01-11 F1 Oncology, Inc. Methods and compositions for transducing lymphocytes and regulating the activity thereof
EP3493827A4 (en) 2016-08-04 2020-02-26 Memorial Sloan-Kettering Cancer Center COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY
CN108250302A (zh) * 2016-12-29 2018-07-06 天津天锐生物科技有限公司 一种多功能蛋白质

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