JP2021529834A5 - - Google Patents
Info
- Publication number
- JP2021529834A5 JP2021529834A5 JP2021522935A JP2021522935A JP2021529834A5 JP 2021529834 A5 JP2021529834 A5 JP 2021529834A5 JP 2021522935 A JP2021522935 A JP 2021522935A JP 2021522935 A JP2021522935 A JP 2021522935A JP 2021529834 A5 JP2021529834 A5 JP 2021529834A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- independently selected
- substituted
- group
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024072451A JP2024102170A (ja) | 2018-07-03 | 2024-04-26 | Sting活性に関連する状態を治療するための化合物および組成物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862693878P | 2018-07-03 | 2018-07-03 | |
| US62/693,878 | 2018-07-03 | ||
| US201962861078P | 2019-06-13 | 2019-06-13 | |
| US62/861,078 | 2019-06-13 | ||
| PCT/US2019/040418 WO2020010155A1 (en) | 2018-07-03 | 2019-07-02 | Compounds and compositions for treating conditions associated with sting activity |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024072451A Division JP2024102170A (ja) | 2018-07-03 | 2024-04-26 | Sting活性に関連する状態を治療するための化合物および組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021529834A JP2021529834A (ja) | 2021-11-04 |
| JP2021529834A5 true JP2021529834A5 (enExample) | 2022-07-11 |
| JP7482122B2 JP7482122B2 (ja) | 2024-05-13 |
Family
ID=67441663
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021522935A Active JP7482122B2 (ja) | 2018-07-03 | 2019-07-02 | Sting活性に関連する状態を治療するための化合物および組成物 |
| JP2024072451A Pending JP2024102170A (ja) | 2018-07-03 | 2024-04-26 | Sting活性に関連する状態を治療するための化合物および組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024072451A Pending JP2024102170A (ja) | 2018-07-03 | 2024-04-26 | Sting活性に関連する状態を治療するための化合物および組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20210236466A1 (enExample) |
| EP (1) | EP3818044A1 (enExample) |
| JP (2) | JP7482122B2 (enExample) |
| CN (1) | CN112823151B (enExample) |
| MA (1) | MA53096A (enExample) |
| WO (1) | WO2020010155A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN120004785A (zh) | 2018-07-03 | 2025-05-16 | 诺华制药股份有限公司 | 用于治疗与sting活性有关的疾病的化合物和组合物 |
| JP2022507697A (ja) * | 2018-11-19 | 2022-01-18 | アイエフエム デュー インコーポレイテッド | Sting活性に関連する状態を治療するための化合物および組成物 |
| JP2022517797A (ja) * | 2019-01-17 | 2022-03-10 | アイエフエム デュー インコーポレイテッド | Sting活性に関連する状態を治療するための化合物および組成物 |
| TW202043198A (zh) * | 2019-01-17 | 2020-12-01 | 美商Ifm Due有限公司 | 用於治療與sting活性相關之病況的化合物及組合物 |
| WO2020232247A1 (en) | 2019-05-14 | 2020-11-19 | Provention Bio, Inc. | Methods and compositions for preventing type 1 diabetes |
| WO2020252240A1 (en) * | 2019-06-14 | 2020-12-17 | Ifm Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
| CN114761804A (zh) | 2019-06-21 | 2022-07-15 | 艾福姆德尤股份有限公司 | 治疗癌症的方法 |
| CN115867278B (zh) * | 2020-04-10 | 2025-02-28 | Ab科学有限公司 | 马赛替尼用于治疗covid-19的用途 |
| TW202200136A (zh) | 2020-04-10 | 2022-01-01 | 日商小野藥品工業股份有限公司 | 癌治療方法 |
| IL298999A (en) | 2020-06-11 | 2023-02-01 | Provention Bio Inc | Methods and compositions for the prevention of type 1 diabetes |
| JP2024500874A (ja) | 2020-12-22 | 2024-01-10 | アイエフエム デュー インコーポレイテッド | がんを処置する方法 |
| EP4267129A1 (en) | 2020-12-22 | 2023-11-01 | IFM Due, Inc. | Methods of treating cancer |
| US20240060982A1 (en) * | 2020-12-22 | 2024-02-22 | Ifm Due, Inc. | Methods of treating cancer |
| EP4267128A1 (en) | 2020-12-22 | 2023-11-01 | IFM Due, Inc. | Methods of treating cancer |
| EP4274824A1 (en) * | 2021-01-08 | 2023-11-15 | IFM Due, Inc. | Heterobicyclic compounds having an urea or analogue and their compositions for treating conditions associated with sting activity |
| JP2024520444A (ja) | 2021-05-24 | 2024-05-24 | プロヴェンション・バイオ・インコーポレイテッド | 1型糖尿病を治療するための方法 |
| IL310724A (en) | 2021-08-10 | 2024-04-01 | Ifm Due Inc | COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CONDITIONS ASSOCIATED WITH STING ACTIVITY |
| CN116789641A (zh) * | 2022-03-17 | 2023-09-22 | 中国科学院上海药物研究所 | 二氢异喹啉类化合物及其医药用途 |
| CN114712365B (zh) * | 2022-06-07 | 2022-08-23 | 山东绿叶制药有限公司 | Trk抑制剂在制备治疗迟发性运动障碍药物中的应用 |
| WO2024064358A1 (en) | 2022-09-23 | 2024-03-28 | Ifm Due, Inc. | Compounds and compositions for treating conditions associated with sting activity |
| CN115960047B (zh) * | 2023-01-10 | 2025-04-15 | 中国药科大学 | 一种3-苯基-1h-吡唑类化合物及其用途 |
| WO2025111251A1 (en) * | 2023-11-20 | 2025-05-30 | Exelixis, Inc. | Compounds that inhibit polo-like kinase 4 |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3563985A (en) * | 1967-12-15 | 1971-02-16 | Fmc Corp | Process for preparing certain acylaminoisothiazoles |
| US4230713A (en) * | 1979-01-19 | 1980-10-28 | Ici Americas Inc. | Heterocyclic tetrahydro-1-alkyl-4-oxo-1H-imidazol-2-ylidene urea and phenyl esters of tetrahydro-1-alkyl-4-oxo-1H-imidazol-2-ylidene carbamic acid compounds |
| DE3332270A1 (de) * | 1983-09-07 | 1985-03-21 | Bayer Ag, 5090 Leverkusen | Herbizide mittel enthaltend metribuzin in kombination mit 1,4-disubstituierten pyrazol-derivaten |
| US5849769A (en) * | 1994-08-24 | 1998-12-15 | Medivir Ab | N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection |
| EP1019394A1 (en) * | 1997-05-22 | 2000-07-19 | G.D. Searle & Co. | PYRAZOLE DERIVATIVES AS p38 KINASE INHIBITORS |
| PT1056725E (pt) * | 1997-12-22 | 2006-09-29 | Bayer Pharmaceuticals Corp | Inibicao da raf-quinase usando ureias heterociclicas substituidas com arilo e heteroarilo |
| GT200100147A (es) * | 2000-07-31 | 2002-06-25 | Derivados de imidazol | |
| UA76977C2 (en) * | 2001-03-02 | 2006-10-16 | Icos Corp | Aryl- and heteroaryl substituted chk1 inhibitors and their use as radiosensitizers and chemosensitizers |
| BR0213562A (pt) * | 2001-10-26 | 2004-08-31 | Aventis Pharma Inc | Benzimidazóis e análogos e seu uso como inibidores de cinases de proteìna |
| US7927613B2 (en) | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
| EP2385041B1 (en) * | 2003-05-01 | 2013-09-18 | Bristol-Myers Squibb Company | Pyrazole-amine compounds useful as kinase inhibitors |
| TWI372050B (en) * | 2003-07-03 | 2012-09-11 | Astex Therapeutics Ltd | (morpholin-4-ylmethyl-1h-benzimidazol-2-yl)-1h-pyrazoles |
| JP2005104968A (ja) * | 2003-09-12 | 2005-04-21 | Sumitomo Chemical Co Ltd | フェニルピラゾール化合物及びその用途 |
| EP1684762A4 (en) * | 2003-11-13 | 2009-06-17 | Ambit Biosciences Corp | UREA DERIVATIVES AS MODULATORS OF KINASE |
| WO2006070198A1 (en) * | 2004-12-30 | 2006-07-06 | Astex Therapeutics Limited | Pyrazole derivatives as that modulate the activity of cdk, gsk and aurora kinases |
| EP1801098A1 (en) * | 2005-12-16 | 2007-06-27 | Merck Sante | 2-Adamantylurea derivatives as selective 11B-HSD1 inhibitors |
| US8497285B2 (en) | 2010-12-03 | 2013-07-30 | The Trustees Of The University Of Pennsylvania | Therapy of autoimmune colitis using a TIP60 inhibitor |
| PT2935227T (pt) * | 2012-12-21 | 2017-12-06 | Chemocentryx Inc | Amidas diazol como antagonistas do recetor ccr1 |
| PE20160080A1 (es) | 2013-05-18 | 2016-02-21 | Aduro Biotech Inc | Composiciones y metodos para activar la senalizacion que depende del estimulador del gen de interferon |
| WO2015039334A1 (en) * | 2013-09-22 | 2015-03-26 | Merck Sharp & Dohme Corp. | TrkA KINASE INHIBITORS, COMPOSITIONS AND METHODS THEREOF |
| CA2927009C (en) | 2013-10-21 | 2019-04-23 | Drexel University | Use of sting agonists to treat chronic hepatitis b virus infection |
| CN103739550B (zh) * | 2014-01-02 | 2016-06-01 | 中国药科大学 | 2,3-二甲基-6-脲-2h-吲唑类化合物及其制备方法与应用 |
| JP2019510802A (ja) * | 2016-04-07 | 2019-04-18 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited | タンパク質調節物質として有用な複素環アミド |
| CN106986860A (zh) * | 2017-05-19 | 2017-07-28 | 南京大学 | 一类含酰胺键的吡唑类抗肿瘤化合物的设计、合成 |
| CN107417478B (zh) * | 2017-06-05 | 2020-05-05 | 南京师范大学 | 一种催化氧化羰基化合成不对称二取代脲的方法 |
| WO2018234807A1 (en) * | 2017-06-22 | 2018-12-27 | Curadev Pharma Limited | Heterocyclic small molecule modulators of human sting |
| EP3790500B1 (en) * | 2018-05-10 | 2022-07-06 | Koninklijke Philips N.V. | Methods and systems for adjusting behavior of oral care device based on status of oral cavity |
-
2019
- 2019-07-02 JP JP2021522935A patent/JP7482122B2/ja active Active
- 2019-07-02 WO PCT/US2019/040418 patent/WO2020010155A1/en not_active Ceased
- 2019-07-02 MA MA053096A patent/MA53096A/fr unknown
- 2019-07-02 CN CN201980057351.7A patent/CN112823151B/zh active Active
- 2019-07-02 EP EP19745422.6A patent/EP3818044A1/en active Pending
- 2019-07-02 US US17/257,225 patent/US20210236466A1/en not_active Abandoned
-
2024
- 2024-04-26 JP JP2024072451A patent/JP2024102170A/ja active Pending
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