JP2021528435A5 - - Google Patents
Info
- Publication number
- JP2021528435A5 JP2021528435A5 JP2020571498A JP2020571498A JP2021528435A5 JP 2021528435 A5 JP2021528435 A5 JP 2021528435A5 JP 2020571498 A JP2020571498 A JP 2020571498A JP 2020571498 A JP2020571498 A JP 2020571498A JP 2021528435 A5 JP2021528435 A5 JP 2021528435A5
- Authority
- JP
- Japan
- Prior art keywords
- antibodies
- mixture
- antibody
- different
- substitution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024086125A JP2024109884A (ja) | 2018-06-22 | 2024-05-28 | ２つ以上の異なる抗体の制御された混合物を産生するための方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18179365 | 2018-06-22 | ||
| EP18179365.4 | 2018-06-22 | ||
| PCT/EP2019/066594 WO2019243626A1 (en) | 2018-06-22 | 2019-06-24 | Method for producing a controlled mixture of two or more different antibodies |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024086125A Division JP2024109884A (ja) | 2018-06-22 | 2024-05-28 | ２つ以上の異なる抗体の制御された混合物を産生するための方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021528435A JP2021528435A (ja) | 2021-10-21 |
| JP2021528435A5 true JP2021528435A5 (OSRAM) | 2022-07-01 |
Family
ID=62841830
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020571498A Pending JP2021528435A (ja) | 2018-06-22 | 2019-06-24 | ２つ以上の異なる抗体の制御された混合物を産生するための方法 |
| JP2024086125A Pending JP2024109884A (ja) | 2018-06-22 | 2024-05-28 | ２つ以上の異なる抗体の制御された混合物を産生するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024086125A Pending JP2024109884A (ja) | 2018-06-22 | 2024-05-28 | ２つ以上の異なる抗体の制御された混合物を産生するための方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US12247065B2 (OSRAM) |
| EP (1) | EP3810649A1 (OSRAM) |
| JP (2) | JP2021528435A (OSRAM) |
| CN (1) | CN112513074A (OSRAM) |
| CA (1) | CA3104390A1 (OSRAM) |
| IL (1) | IL279528A (OSRAM) |
| MA (1) | MA52945A (OSRAM) |
| SG (1) | SG11202012713RA (OSRAM) |
| WO (1) | WO2019243626A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI874341B (zh) | 2018-12-18 | 2025-03-01 | 美商健生生物科技公司 | 產生異二聚體抗體之方法 |
| US20230089196A1 (en) | 2020-02-21 | 2023-03-23 | Genmab B.V. | Methods for the quantification of glycoproteins |
| MX2024000501A (es) * | 2021-07-14 | 2024-01-31 | Jiangsu Hengrui Pharmaceuticals Co Ltd | Molecula de union a antigeno que se une especificamente a hgfr y egfr, y su uso farmaceutico. |
| WO2024109914A1 (zh) * | 2022-11-24 | 2024-05-30 | 江苏恒瑞医药股份有限公司 | 一种包含特异性结合hgfr和egfr的双特异性抗体的药物组合物 |
| WO2025003280A1 (en) * | 2023-06-30 | 2025-01-02 | Genmab A/S | Antibodies binding to fibroblast activation protein alpha and death receptor 4 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE255131T1 (de) | 1991-06-14 | 2003-12-15 | Genentech Inc | Humanisierter heregulin antikörper |
| GB9203459D0 (en) | 1992-02-19 | 1992-04-08 | Scotgen Ltd | Antibodies with germ-line variable regions |
| DE59309332D1 (de) * | 1993-12-27 | 1999-03-04 | Rotkreuzstiftung Zentratrallab | Verfahren zur Herstellung eines Konzentrates von Anti-D-Immunoglobulin G und pharmazeutische Zusammensetzung, die dieses enthält |
| EP1097172A1 (en) | 1998-07-21 | 2001-05-09 | Genmab A/S | Anti hepatitis c virus antibody and uses thereof |
| WO2002100348A2 (en) | 2001-06-13 | 2002-12-19 | Genmab A/S | Human monoclonal antibodies to epidermal growth factor receptor (egfr) |
| EP2314629B2 (en) * | 2002-07-18 | 2022-11-16 | Merus N.V. | Recombinant production of mixtures of antibodies |
| KR20110017020A (ko) | 2002-10-17 | 2011-02-18 | 젠맵 에이/에스 | Ｃｄ20에 대한 인간 모노클로날 항체 |
| CA2512647C (en) | 2003-01-07 | 2013-10-08 | Symphogen A/S | Method for manufacturing recombinant polyclonal proteins |
| MX2007000644A (es) * | 2004-07-20 | 2007-03-28 | Symphogen As | Anticuerpo policlonal recombinante anti-rhesus d y metodos de fabricacion. |
| PL1787126T3 (pl) * | 2004-07-20 | 2010-03-31 | Symphogen As | Sposób charakteryzowania poliklonalnej linii komórkowej |
| EP2009101B1 (en) | 2006-03-31 | 2017-10-25 | Chugai Seiyaku Kabushiki Kaisha | Antibody modification method for purifying bispecific antibody |
| CL2007003622A1 (es) | 2006-12-13 | 2009-08-07 | Medarex Inc | Anticuerpo monoclonal humano anti-cd19; composicion que lo comprende; y metodo de inhibicion del crecimiento de celulas tumorales. |
| HRP20100640T1 (hr) | 2007-05-25 | 2010-12-31 | Symphogen A/S | Postupak proizvodnje rekombinantnog poliklonskog proteina |
| CA2722348A1 (en) * | 2008-04-23 | 2009-10-29 | Symphogen A/S | Methods for manufacturing a polyclonal protein |
| EP2393927B1 (en) | 2009-02-09 | 2014-12-31 | MorphoSys AG | Production of oligoclonal mixtures of immunoglobulins in single cells |
| LT2975051T (lt) | 2009-06-26 | 2021-07-12 | Regeneron Pharmaceuticals, Inc. | Lengvai išskiriami bispecifiniai antikūnai su natyvios formos imunoglobulinu |
| MX338932B (es) | 2010-03-12 | 2016-05-06 | Immunogen Inc | Moleculas de union cd37 y sus inmunoconjugados. |
| JP6040148B2 (ja) | 2010-04-20 | 2016-12-07 | ゲンマブ エー／エス | ヘテロ二量体抗体Ｆｃ含有タンパク質およびその産生方法 |
| NZ604007A (en) | 2010-05-27 | 2015-03-27 | Genmab As | Monoclonal antibodies against her2 epitope |
| DK2640743T3 (en) | 2010-11-16 | 2017-01-23 | Excelimmune Inc | PROCEDURES FOR THE PREPARATION OF RECOMBINANT PROTEINS |
| WO2012143523A1 (en) | 2011-04-20 | 2012-10-26 | Genmab A/S | Bispecifc antibodies against her2 |
| UA117901C2 (uk) | 2011-07-06 | 2018-10-25 | Ґенмаб Б.В. | Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування |
| ES2767135T3 (es) | 2011-10-19 | 2020-06-16 | Novimmune Sa | Métodos para purificar anticuerpos |
| WO2013136186A2 (en) * | 2012-03-13 | 2013-09-19 | Novimmune S.A. | Readily isolated bispecific antibodies with native immunoglobulin format |
| HK1215950A1 (zh) | 2012-09-25 | 2016-09-30 | 艾科诺斯科技股份有限公司 | 异源二聚免疫球蛋白的纯化 |
| AU2013372331A1 (en) | 2013-01-10 | 2015-07-23 | Genmab B.V. | Human IgG1 Fc region variants and uses thereof |
| CN105324393A (zh) | 2013-05-13 | 2016-02-10 | 米迪缪尼有限公司 | 具有最小单体分离的重组多克隆抗体多聚体的分离 |
| EP3169706B1 (en) | 2014-07-11 | 2019-12-04 | Genmab A/S | Antibodies binding axl |
| EP3233907B1 (en) | 2014-12-19 | 2021-03-03 | Genmab A/S | Rodent bispecific heterodimeric proteins |
| ES2973885T3 (es) | 2015-07-09 | 2024-06-24 | Genmab As | Anticuerpos biespecíficos y multiespecíficos y método para aislarlos |
| KR20230041834A (ko) | 2016-08-16 | 2023-03-24 | 리제너론 파아마슈티컬스, 인크. | 혼합물로부터 개별 항체들을 정량하는 방법 |
-
2019
- 2019-06-24 EP EP19734332.0A patent/EP3810649A1/en active Pending
- 2019-06-24 WO PCT/EP2019/066594 patent/WO2019243626A1/en not_active Ceased
- 2019-06-24 US US17/253,286 patent/US12247065B2/en active Active
- 2019-06-24 MA MA052945A patent/MA52945A/fr unknown
- 2019-06-24 JP JP2020571498A patent/JP2021528435A/ja active Pending
- 2019-06-24 SG SG11202012713RA patent/SG11202012713RA/en unknown
- 2019-06-24 CA CA3104390A patent/CA3104390A1/en active Pending
- 2019-06-24 CN CN201980050655.0A patent/CN112513074A/zh active Pending
-
2020
- 2020-12-17 IL IL279528A patent/IL279528A/en unknown
-
2024
- 2024-05-28 JP JP2024086125A patent/JP2024109884A/ja active Pending
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