JP2021527700A5 - - Google Patents

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Publication number
JP2021527700A5
JP2021527700A5 JP2020571400A JP2020571400A JP2021527700A5 JP 2021527700 A5 JP2021527700 A5 JP 2021527700A5 JP 2020571400 A JP2020571400 A JP 2020571400A JP 2020571400 A JP2020571400 A JP 2020571400A JP 2021527700 A5 JP2021527700 A5 JP 2021527700A5
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JP
Japan
Prior art keywords
protein
subunit
amino acid
charge
heterodimer
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020571400A
Other languages
English (en)
Japanese (ja)
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JP2021527700A (ja
JP7439372B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/038451 external-priority patent/WO2019246508A1/en
Publication of JP2021527700A publication Critical patent/JP2021527700A/ja
Publication of JP2021527700A5 publication Critical patent/JP2021527700A5/ja
Priority to JP2023098823A priority Critical patent/JP7452932B2/ja
Application granted granted Critical
Publication of JP7439372B2 publication Critical patent/JP7439372B2/ja
Priority to JP2024032407A priority patent/JP2024057087A/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2020571400A 2018-06-21 2019-06-21 ヘテロ二量体タンパク質及びその使用 Active JP7439372B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2023098823A JP7452932B2 (ja) 2018-06-21 2023-06-15 ヘテロ二量体タンパク質及びその使用
JP2024032407A JP2024057087A (ja) 2018-06-21 2024-03-04 ヘテロ二量体タンパク質及びその使用

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862688167P 2018-06-21 2018-06-21
US62/688,167 2018-06-21
US201862703248P 2018-07-25 2018-07-25
US62/703,248 2018-07-25
PCT/US2019/038451 WO2019246508A1 (en) 2018-06-21 2019-06-21 Heterodimeric proteins and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023098823A Division JP7452932B2 (ja) 2018-06-21 2023-06-15 ヘテロ二量体タンパク質及びその使用

Publications (3)

Publication Number Publication Date
JP2021527700A JP2021527700A (ja) 2021-10-14
JP2021527700A5 true JP2021527700A5 (https=) 2022-06-28
JP7439372B2 JP7439372B2 (ja) 2024-02-28

Family

ID=68983045

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020571400A Active JP7439372B2 (ja) 2018-06-21 2019-06-21 ヘテロ二量体タンパク質及びその使用
JP2023098823A Active JP7452932B2 (ja) 2018-06-21 2023-06-15 ヘテロ二量体タンパク質及びその使用
JP2024032407A Pending JP2024057087A (ja) 2018-06-21 2024-03-04 ヘテロ二量体タンパク質及びその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2023098823A Active JP7452932B2 (ja) 2018-06-21 2023-06-15 ヘテロ二量体タンパク質及びその使用
JP2024032407A Pending JP2024057087A (ja) 2018-06-21 2024-03-04 ヘテロ二量体タンパク質及びその使用

Country Status (10)

Country Link
US (3) US10995127B2 (https=)
EP (1) EP3810172A4 (https=)
JP (3) JP7439372B2 (https=)
KR (1) KR20210025054A (https=)
CN (1) CN112566650A (https=)
AU (1) AU2019290192A1 (https=)
BR (1) BR112020026112A2 (https=)
CA (1) CA3103975A1 (https=)
MX (1) MX2020014031A (https=)
WO (1) WO2019246508A1 (https=)

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CN112566650A (zh) * 2018-06-21 2021-03-26 沙塔克实验室有限公司 异二聚体蛋白及其用途
CA3149583A1 (en) * 2019-08-30 2021-03-04 Shattuck Labs, Inc. Chimeric proteins in autoimmunity
WO2021202354A1 (en) * 2020-03-30 2021-10-07 Proviva Therapeutics (Hong Kong) Limited Il-2/il-15 compositions and methods of use thereof
US12012441B2 (en) 2020-10-26 2024-06-18 Neptune Biosciences Llc Engineered human IL-21 cytokines and methods for using the same
US20240262893A1 (en) 2021-05-12 2024-08-08 Applied Biomedical Science Institute Binding polypeptides against sars cov-2 and uses thereof
JP2024521987A (ja) 2021-05-12 2024-06-05 アプライド バイオメディカル サイエンス インスティチュート ジスルフィド結合した結合ポリペプチドのスクリーニング及び発現の方法
EP4511054A2 (en) * 2022-04-20 2025-02-26 Neptune Biosciences LLC Orthogonal il-21 receptor/cytokine systems
CA3256783A1 (en) 2022-05-16 2023-11-23 Enkefalos Biosciences, Llc Blood-brain barrier translocation peptides and associated molecules and their methods of use
WO2024019984A1 (en) * 2022-07-18 2024-01-25 Cargo Therapeutics, Inc. Cytokine receptor switch polypeptides and uses thereof
AU2023379740A1 (en) 2022-11-16 2025-05-29 Applied Biomedical Science Institute Fusion polypeptides and binding peptides and methods for producing and using same
WO2024123812A1 (en) 2022-12-05 2024-06-13 Shattuck Labs, Inc. Fusion proteins for the treatment of cardiometabolic diseases
WO2025133115A1 (en) * 2023-12-21 2025-06-26 Ose Immunotherapeutics Lipid-based nanoparticles comprising il-35
WO2025140436A1 (zh) * 2023-12-27 2025-07-03 上海药明生物技术有限公司 重组il-27蛋白及其制备方法
CN117986386B (zh) * 2024-02-06 2024-11-29 康立泰生物医药(青岛)有限公司 重组人白细胞介素-35及其制备方法和应用
US20260035414A1 (en) * 2024-08-01 2026-02-05 Twilight Bioscience, Inc. Herv-k (hml-2) env analog fusion proteins for antigen specific immunotherapy and methods of use

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IT1274350B (it) * 1994-12-06 1997-07-17 Angeletti P Ist Richerche Bio Antagonisti di interleuchina-6(il-6) che consistono di forme solubili del ricettore alfa di il-6, mutate nell'interfaccia che si lega a gp 130
BR9707589A (pt) * 1996-02-20 2000-01-04 Applied Research Systems Proteìna hìbrida, molécula de dna, vetor de expressão, célula hospedeira, composição farmacêutica e processos para produzir proteìna hìbrida e para induzir maturação folicular.
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JP6594855B2 (ja) * 2013-03-15 2019-10-23 ゼンコア インコーポレイテッド ヘテロ二量体タンパク質
US10017545B2 (en) * 2013-06-03 2018-07-10 University Of Maryland, College Park Compositions and vaccines comprising vesicles and methods of using the same
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CN112566650A (zh) * 2018-06-21 2021-03-26 沙塔克实验室有限公司 异二聚体蛋白及其用途
US11098093B2 (en) * 2019-01-07 2021-08-24 Shattuck Labs, Inc. Heterodimeric proteins for modulating gamma delta T cells
CA3149583A1 (en) * 2019-08-30 2021-03-04 Shattuck Labs, Inc. Chimeric proteins in autoimmunity

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