JP2021525518A5 - - Google Patents
Info
- Publication number
- JP2021525518A5 JP2021525518A5 JP2020566646A JP2020566646A JP2021525518A5 JP 2021525518 A5 JP2021525518 A5 JP 2021525518A5 JP 2020566646 A JP2020566646 A JP 2020566646A JP 2020566646 A JP2020566646 A JP 2020566646A JP 2021525518 A5 JP2021525518 A5 JP 2021525518A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- cells
- population
- genome
- immune effector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862678886P | 2018-05-31 | 2018-05-31 | |
| US62/678,886 | 2018-05-31 | ||
| PCT/US2019/034959 WO2019232409A1 (en) | 2018-05-31 | 2019-05-31 | Methods for genome editing and activation of cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021525518A JP2021525518A (ja) | 2021-09-27 |
| JP2021525518A5 true JP2021525518A5 (enExample) | 2022-06-08 |
Family
ID=68697155
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020566646A Pending JP2021525518A (ja) | 2018-05-31 | 2019-05-31 | 細胞をゲノム編集及び活性化するための方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20200109364A1 (enExample) |
| EP (1) | EP3801574A4 (enExample) |
| JP (1) | JP2021525518A (enExample) |
| CN (1) | CN112867498A (enExample) |
| WO (1) | WO2019232409A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102546839B1 (ko) | 2016-08-03 | 2023-06-23 | 워싱턴 유니버시티 | 키메라 항원 수용체를 이용한 t 세포 악성종양의 치료를 위한 car-t 세포의 유전자 편집 |
| CA3287539A1 (en) | 2017-06-21 | 2026-03-02 | Icell Gene Therapeutics Llc | CHIMERIC ANTIGEN RECEPTORS (CARs), COMPOSITIONS AND METHODS THEREOF |
| EP3802798A4 (en) * | 2018-05-31 | 2022-05-11 | Washington University | CHIMERIC ANTIGEN RECEPTOR T CELLS (CAR-T) FOR TREATMENT OF CANCER |
| WO2020018620A1 (en) * | 2018-07-17 | 2020-01-23 | The Regents Of The University Of California | Chimeric antigen receptor t cells derived from immunoengineered pluripotent stem cells |
| US12221622B2 (en) | 2019-05-10 | 2025-02-11 | The Regents Of The University Of California | Modified pluripotent cells |
| US11162079B2 (en) | 2019-05-10 | 2021-11-02 | The Regents Of The University Of California | Blood type O Rh-hypo-immunogenic pluripotent cells |
| WO2021129927A1 (en) * | 2019-12-23 | 2021-07-01 | Biontech Cell & Gene Therapies Gmbh | Treatment with immune effector cells engineered to express an antigen receptor |
| WO2021223359A1 (en) * | 2020-05-06 | 2021-11-11 | Gracell Biotechnologies (Shanghai) Co., Ltd. | Compositions and methods for t cell engineering |
| CN111849910B (zh) * | 2020-05-27 | 2021-06-15 | 南京北恒生物科技有限公司 | 工程化免疫细胞及其用途 |
| EP4219707A4 (en) * | 2020-09-24 | 2024-11-13 | Kyoto University | METHOD FOR PRODUCING AN EFFECTOR CELL WITH DESIRED SPECIFICITY |
| US11661459B2 (en) | 2020-12-03 | 2023-05-30 | Century Therapeutics, Inc. | Artificial cell death polypeptide for chimeric antigen receptor and uses thereof |
| KR20230118887A (ko) | 2020-12-03 | 2023-08-14 | 센츄리 쎄라퓨틱스 인코포레이티드 | 유전자 조작 세포 및 이의 용도 |
| CN112980800A (zh) * | 2021-03-08 | 2021-06-18 | 河北森朗生物科技有限公司 | Car-t细胞、其构建方法及其应用 |
| EP4326291A4 (en) * | 2021-04-20 | 2025-03-12 | Board of Regents, The University of Texas System | Methods and compositions for genetic modification and therapeutic use of immune cells |
| CN113430202A (zh) * | 2021-08-26 | 2021-09-24 | 山东兴瑞生物科技有限公司 | 一种具有高敲除率的人PD1基因sgRNA及含有该sgRNA的质粒、T细胞 |
| CN113462652A (zh) * | 2021-09-06 | 2021-10-01 | 阿思科力(苏州)生物科技有限公司 | 细胞、免疫治疗产品、基因编辑方法、细胞制备方法及应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015066262A1 (en) * | 2013-11-04 | 2015-05-07 | Trustees Of Dartmouth College | Methods for preventing toxicity of adoptive cell therapy |
| US20170335331A1 (en) * | 2014-10-31 | 2017-11-23 | The Trustees Of The University Of Pennsylvania | Altering Gene Expression in CART Cells and Uses Thereof |
| WO2016073381A1 (en) * | 2014-11-03 | 2016-05-12 | Cerus Corporation | Compositions and methods for improved car-t cell therapies |
| JP7237449B2 (ja) * | 2015-02-27 | 2023-03-13 | アイセル・ジーン・セラピューティクス・エルエルシー | 血液系腫瘍を標的としたキメラ抗体受容体（ＣＡＲｓ）の構成およびその使用方法 |
| AU2016243583B2 (en) * | 2015-03-27 | 2022-03-10 | President And Fellows Of Harvard College | Modified T cells and methods of making and using the same |
| CU24649B1 (es) * | 2016-03-19 | 2023-02-13 | Exuma Biotech Corp | Retrovirus recombinantes incompetentes de replicación para la transducción de linfocitos y expansión regulada de los mismos |
| US20190161530A1 (en) * | 2016-04-07 | 2019-05-30 | Bluebird Bio, Inc. | Chimeric antigen receptor t cell compositions |
| US20190136230A1 (en) * | 2016-05-06 | 2019-05-09 | Juno Therapeutics, Inc. | Genetically engineered cells and methods of making the same |
| KR102546839B1 (ko) * | 2016-08-03 | 2023-06-23 | 워싱턴 유니버시티 | 키메라 항원 수용체를 이용한 t 세포 악성종양의 치료를 위한 car-t 세포의 유전자 편집 |
| GB201616699D0 (en) * | 2016-09-30 | 2016-11-16 | Mab Designs Ltd | Antibodies |
-
2019
- 2019-05-31 JP JP2020566646A patent/JP2021525518A/ja active Pending
- 2019-05-31 EP EP19812244.2A patent/EP3801574A4/en active Pending
- 2019-05-31 US US16/428,348 patent/US20200109364A1/en not_active Abandoned
- 2019-05-31 WO PCT/US2019/034959 patent/WO2019232409A1/en not_active Ceased
- 2019-05-31 CN CN201980050878.7A patent/CN112867498A/zh active Pending
-
2024
- 2024-05-13 US US18/662,838 patent/US20250043243A1/en active Pending
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