JP2021525275A5 - - Google Patents
Info
- Publication number
- JP2021525275A5 JP2021525275A5 JP2020567741A JP2020567741A JP2021525275A5 JP 2021525275 A5 JP2021525275 A5 JP 2021525275A5 JP 2020567741 A JP2020567741 A JP 2020567741A JP 2020567741 A JP2020567741 A JP 2020567741A JP 2021525275 A5 JP2021525275 A5 JP 2021525275A5
- Authority
- JP
- Japan
- Prior art keywords
- solvent
- ray diffraction
- crystalline form
- hydrazide
- dimethylphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023218036A JP2024038090A (ja) | 2018-02-21 | 2023-12-25 | ２，２，２－トリフルオロ酢酸１－（２，４－ジメチルフェニル）－２－［（３－メトキシフェニル）メチレン］ ヒドラジド多形体およびその製造方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862633441P | 2018-02-21 | 2018-02-21 | |
| US62/633,441 | 2018-02-21 | ||
| PCT/US2019/018835 WO2019164997A1 (en) | 2018-02-21 | 2019-02-20 | 2,2,2-trifluoroacetic acid 1-(2,4-dimethylphenyl)-2-[(3-methoxyphenyl) methylene] hydrazide polymorphs and method of making the same |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023218036A Division JP2024038090A (ja) | 2018-02-21 | 2023-12-25 | ２，２，２－トリフルオロ酢酸１－（２，４－ジメチルフェニル）－２－［（３－メトキシフェニル）メチレン］ ヒドラジド多形体およびその製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021525275A JP2021525275A (ja) | 2021-09-24 |
| JP2021525275A5 true JP2021525275A5 (cg-RX-API-DMAC10.html) | 2022-03-02 |
| JP7883832B2 JP7883832B2 (ja) | 2026-07-02 |
Family
ID=67686904
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020567741A Active JP7883832B2 (ja) | 2018-02-21 | 2019-02-20 | ２，２，２－トリフルオロ酢酸１－（２，４－ジメチルフェニル）－２－［（３－メトキシフェニル）メチレン］ ヒドラジド多形体およびその製造方法 |
| JP2023218036A Pending JP2024038090A (ja) | 2018-02-21 | 2023-12-25 | ２，２，２－トリフルオロ酢酸１－（２，４－ジメチルフェニル）－２－［（３－メトキシフェニル）メチレン］ ヒドラジド多形体およびその製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023218036A Pending JP2024038090A (ja) | 2018-02-21 | 2023-12-25 | ２，２，２－トリフルオロ酢酸１－（２，４－ジメチルフェニル）－２－［（３－メトキシフェニル）メチレン］ ヒドラジド多形体およびその製造方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10968167B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP3755316A4 (cg-RX-API-DMAC10.html) |
| JP (2) | JP7883832B2 (cg-RX-API-DMAC10.html) |
| CN (1) | CN113747892A (cg-RX-API-DMAC10.html) |
| CA (1) | CA3091782A1 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2019164997A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3755316A4 (en) * | 2018-02-21 | 2022-05-25 | Abrexa Pharmaceuticals, Inc. | 2,2,2-TRIFLUOROACETIC ACID 1-(2,4-DIMETHYLPHENYL)-2-[(3-METHOXYPHENYL)-METHYLENE]HYDRAZIDE POLYMORPHS AND PROCESS FOR THEIR PREPARATION |
| WO2021222438A1 (en) * | 2020-04-28 | 2021-11-04 | Abrexa Pharmaceuticals, Inc. | Compounds for prevention and treatment of post-intensive care cognitive dysfunction and cognitive dysfunction resulting from respiratory distress |
| JP2026518142A (ja) * | 2023-05-26 | 2026-06-04 | アブレキサ ファーマスーティカルズ，インコーポレイテッド | 臓器保存および臓器移植に使用するための化合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8779002B2 (en) | 2007-10-15 | 2014-07-15 | Salk Institute For Biological Studies | Methods for treating a variety of diseases and conditions, and compounds useful therefor |
| CN105801496B (zh) * | 2014-12-31 | 2018-03-13 | 广州喜鹊医药有限公司 | 三氟乙酰肼类化合物及其制备方法和在制药中的应用 |
| WO2017015660A1 (en) * | 2015-07-23 | 2017-01-26 | Salk Institute For Biological Studies | Prevention and treatment of aging and neurodegenerative diseases |
| EP3755316A4 (en) * | 2018-02-21 | 2022-05-25 | Abrexa Pharmaceuticals, Inc. | 2,2,2-TRIFLUOROACETIC ACID 1-(2,4-DIMETHYLPHENYL)-2-[(3-METHOXYPHENYL)-METHYLENE]HYDRAZIDE POLYMORPHS AND PROCESS FOR THEIR PREPARATION |
-
2019
- 2019-02-20 EP EP19758167.1A patent/EP3755316A4/en active Pending
- 2019-02-20 WO PCT/US2019/018835 patent/WO2019164997A1/en not_active Ceased
- 2019-02-20 CN CN201980025349.1A patent/CN113747892A/zh active Pending
- 2019-02-20 CA CA3091782A patent/CA3091782A1/en active Pending
- 2019-02-20 US US16/975,054 patent/US10968167B2/en active Active
- 2019-02-20 JP JP2020567741A patent/JP7883832B2/ja active Active
-
2021
- 2021-01-17 US US17/151,198 patent/US11584711B2/en active Active
-
2023
- 2023-12-25 JP JP2023218036A patent/JP2024038090A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2577331C2 (ru) | Кристаллическое основание миноциклина и способы его получения | |
| JP7181896B2 (ja) | オメカムティブメカルビルの合成 | |
| EP2896617B1 (de) | Verfahren zur herstellung von substituierten (z)-alpha-fluoro-beta-amino-acrylaldehyden | |
| KR102746929B1 (ko) | 프로테인 카이네이즈에 대한 선택적 억제제의 합성에 유용한 중간체 및 이의 제조방법 | |
| JP3779155B2 (ja) | クラリスロマイシン結晶型ｉｉの製造方法 | |
| HRP20010514A2 (en) | Telmisartan polymorphs, methods for producing same and their use in the preparation of a medicament | |
| EP3668857A1 (en) | Processes for the preparation of niraparib and intermediates thereof | |
| JP2610889B2 (ja) | 新規架橋アデニン誘導体 | |
| JP2006513185A5 (cg-RX-API-DMAC10.html) | ||
| JP2023078126A (ja) | 光学活性ジアザスピロ［４．５］デカン誘導体の分割 | |
| JP2021504458A (ja) | サリチルアミド酢酸塩の製造方法 | |
| AU2010272364A1 (en) | Process for preparing levosimendan and intermediates for use in the process | |
| CN107868087B (zh) | 一种制备吡咯并吲哚类衍生物的方法 | |
| JPH0478635B2 (cg-RX-API-DMAC10.html) | ||
| KR20100028543A (ko) | 아로마타제 억제제의 제조 방법 | |
| CA1081694A (en) | Rifamycin compounds | |
| CN117603094B (zh) | 一种氨基保护的2-氨基甲基烯酸衍生物的合成方法 | |
| KR20220044684A (ko) | 살리실아민 아세테이트 제조방법 | |
| JP2001518106A (ja) | １，３−ジ置換２−ニトログアニジンの製造法 | |
| ES2761821T3 (es) | Proceso para la preparación de intermedios útiles en la síntesis de eluxadolina | |
| CN103819466B (zh) | 一种药物活性化合物Cephalandole A的合成方法 | |
| KR101201203B1 (ko) | 고순도 메티오졸린의 공업적 제조방법 | |
| EP1597263B1 (en) | Preparation of a trans-calanolide ketone intermediate and chiral separation of calanolide alcohols to give racemic calanolide a | |
| RU2417995C1 (ru) | Способ получения 3-(2-замещенных-1,3-оксазол-4-ил)пиридин-2(1н)-онов | |
| WO2015162551A1 (en) | Process for the preparation of apixaban |