JP2021524485A - パラ結核症のための免疫原性組成物 - Google Patents

パラ結核症のための免疫原性組成物 Download PDF

Info

Publication number
JP2021524485A
JP2021524485A JP2021500530A JP2021500530A JP2021524485A JP 2021524485 A JP2021524485 A JP 2021524485A JP 2021500530 A JP2021500530 A JP 2021500530A JP 2021500530 A JP2021500530 A JP 2021500530A JP 2021524485 A JP2021524485 A JP 2021524485A
Authority
JP
Japan
Prior art keywords
polypeptide
amino acid
acid sequence
seq
map
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2021500530A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021524485A5 (https=
Inventor
ハーモン−テイラー,ジョン
Original Assignee
ハブ バクシーンズ リミテッド
ハブ バクシーンズ リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ハブ バクシーンズ リミテッド, ハブ バクシーンズ リミテッド filed Critical ハブ バクシーンズ リミテッド
Publication of JP2021524485A publication Critical patent/JP2021524485A/ja
Publication of JP2021524485A5 publication Critical patent/JP2021524485A5/ja
Priority to JP2024109065A priority Critical patent/JP2024153666A/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/04Mycobacterium, e.g. Mycobacterium tuberculosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5256Virus expressing foreign proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2021500530A 2018-07-11 2019-07-10 パラ結核症のための免疫原性組成物 Pending JP2021524485A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024109065A JP2024153666A (ja) 2018-07-11 2024-07-05 パラ結核症のための免疫原性組成物

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1811382.9A GB201811382D0 (en) 2018-07-11 2018-07-11 Vaccine
GB1811382.9 2018-07-11
PCT/GB2019/051933 WO2020012177A1 (en) 2018-07-11 2019-07-10 Immunogenic composition for paratuberculosis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024109065A Division JP2024153666A (ja) 2018-07-11 2024-07-05 パラ結核症のための免疫原性組成物

Publications (2)

Publication Number Publication Date
JP2021524485A true JP2021524485A (ja) 2021-09-13
JP2021524485A5 JP2021524485A5 (https=) 2022-07-12

Family

ID=63273113

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021500530A Pending JP2021524485A (ja) 2018-07-11 2019-07-10 パラ結核症のための免疫原性組成物
JP2024109065A Pending JP2024153666A (ja) 2018-07-11 2024-07-05 パラ結核症のための免疫原性組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024109065A Pending JP2024153666A (ja) 2018-07-11 2024-07-05 パラ結核症のための免疫原性組成物

Country Status (14)

Country Link
US (2) US12186382B2 (https=)
EP (1) EP3820507A1 (https=)
JP (2) JP2021524485A (https=)
KR (1) KR20210033490A (https=)
CN (1) CN113329765A (https=)
AU (1) AU2019301899A1 (https=)
BR (1) BR112021000312A2 (https=)
CA (1) CA3105763A1 (https=)
GB (1) GB201811382D0 (https=)
IL (1) IL280070B2 (https=)
MA (1) MA53131A (https=)
MX (1) MX2020013924A (https=)
SG (1) SG11202100120TA (https=)
WO (1) WO2020012177A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020507084A (ja) * 2017-01-11 2020-03-05 ハブ バクシーンズ リミテッド 診断

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2026041756A1 (en) 2024-08-21 2026-02-26 Hav Vaccines Limited Treatment of crohn's disease by mycobacterium avium subsp. paratuberculosis agent

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5168062A (en) 1985-01-30 1992-12-01 University Of Iowa Research Foundation Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence
GB8709803D0 (en) 1987-04-24 1987-05-28 Mcfadden J J Treatment of crohn's disease &c
US5225324A (en) 1987-04-24 1993-07-06 Bioscience International, Inc. Diagnostics for mycobacteria in public health, medical, and veterinary practice
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
CA2489769A1 (en) 1989-03-21 1990-10-04 Philip L. Felgner Expression of exogenous polynucleotide sequences in a vertebrate
US5399346A (en) 1989-06-14 1995-03-21 The United States Of America As Represented By The Department Of Health And Human Services Gene therapy
US5279833A (en) 1990-04-04 1994-01-18 Yale University Liposomal transfection of nucleic acids into animal cells
US5283185A (en) 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
CA2131620A1 (en) 1992-03-20 1993-09-30 Louis C. Smith A dna transporter system and method of use
WO1993019768A1 (en) 1992-04-03 1993-10-14 The Regents Of The University Of California Self-assembling polynucleotide delivery system
US5651981A (en) 1994-03-29 1997-07-29 Northwestern University Cationic phospholipids for transfection
US5527928A (en) 1994-09-30 1996-06-18 Nantz; Michael H. Cationic transport reagents
GB9526178D0 (en) 1995-12-21 1996-02-21 Taylor John Hermon Novel polynuceotides and polypeptides in pathogenic mycobacteria and their use as diagnostics,vaccines and targets for chemotherapy
GB9806093D0 (en) 1998-03-20 1998-05-20 Taylor John Hermon Diagnostics and vaccines for mycobacterial infections of animals and humans
US7074559B2 (en) * 2002-03-06 2006-07-11 Refents of the University of Minnesota Mycobacterial diagnostics
AU2006277828B2 (en) 2005-08-09 2012-02-02 Hav Vaccines Limited Immunogenic constructs
US8609097B2 (en) 2009-06-10 2013-12-17 Hoffmann-La Roche Inc. Use of an anti-Tau pS422 antibody for the treatment of brain diseases
JP2013500326A (ja) 2009-07-30 2013-01-07 ファイザー バクシーンズ エルエルシー 抗原性タウペプチドおよびその使用
CA2839865A1 (en) 2011-05-19 2012-11-22 University Of Central Florida Research Foundation, Inc. Microbe detection via hybridizing magnetic relaxation nanosensors
WO2014016737A1 (en) 2012-07-24 2014-01-30 Pfizer Inc. Novel chicken monoclonal antibodies against human phosphorylated tau and uses thereof
US20160228528A1 (en) 2013-01-28 2016-08-11 Janssen Sciences Ireland Uc A single or multistage mycobacterium avium subsp. paratuberculosis subunit vaccine
GB201700487D0 (en) * 2017-01-11 2017-02-22 Hermon-Taylor John Diagnostic

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020507084A (ja) * 2017-01-11 2020-03-05 ハブ バクシーンズ リミテッド 診断
JP7418215B2 (ja) 2017-01-11 2024-01-19 ハブ バクシーンズ リミテッド 診断

Also Published As

Publication number Publication date
MA53131A (fr) 2021-05-19
US12186382B2 (en) 2025-01-07
AU2019301899A1 (en) 2021-01-14
CA3105763A1 (en) 2020-01-16
IL280070B2 (en) 2024-04-01
WO2020012177A1 (en) 2020-01-16
GB201811382D0 (en) 2018-08-29
SG11202100120TA (en) 2021-02-25
BR112021000312A2 (pt) 2021-04-13
JP2024153666A (ja) 2024-10-29
IL280070B1 (en) 2023-12-01
US20210338791A1 (en) 2021-11-04
IL280070A (en) 2021-03-01
EP3820507A1 (en) 2021-05-19
CN113329765A (zh) 2021-08-31
KR20210033490A (ko) 2021-03-26
US20250152691A1 (en) 2025-05-15
MX2020013924A (es) 2021-03-02

Similar Documents

Publication Publication Date Title
CN102905724B (zh) 分枝杆菌抗原组合物
JP5219808B2 (ja) 改良された結核ワクチン
RU2702194C2 (ru) Композиция микобактериального антигена
US20250152691A1 (en) Immunogenic composition for paratuberculosis
JP2008245644A (ja) 結核の免疫治療および診断のための化合物およびそれらの使用方法
JP2003524021A (ja) 悪性中皮腫の診断および治療のための組成物および方法
EA013016B1 (ru) Способы и средства диагностики, профилактики и лечения инфекций mycobacterium и заболевания туберкулезом
CA2884918C (en) Salmonid alphavirus and uses thereof
JP7035063B2 (ja) phoP-phoRを過剰発現する組換えBCG
RU2559782C2 (ru) Набор для детекции спор, происходящих из микобактерий
Bull et al. A novel multi-antigen virally vectored vaccine against Mycobacterium avium subspecies paratuberculosis
JP2015524802A (ja) キメラospa分子を含む組成物およびその使用方法
JP2004041219A (ja) アクチノバチルス・プレウロニウモニアからのタンパク質
JP2016513078A (ja) 一段階または多段階のトリ型結核菌亜種副結核症サブユニット・ワクチン
Roupie et al. Immunogenicity and protective efficacy of DNA vaccines encoding MAP0586c and MAP4308c of Mycobacterium avium subsp. paratuberculosis secretome
KR20190082229A (ko) 스타필로코커스 감염에 대한 백신 구성체 및 이의 용도
RS54963B1 (sr) Polipeptidi stereptococcus suis-a i polinukleotidi koji ih kodiraju i njihova primena u vakcinama i dijagnostici
JP2004514451A (ja) マイコバクテリア感染に対する防御
JP5244593B2 (ja) 免疫原性構築物
JPH11146794A (ja) mraY
CN108794636A (zh) 一种表位多肽串联混合物在抗立氏立克次体的免疫保护中的应用
JP2000510339A (ja) インビボで発現されるB.burgdorferiポリペプチド
Bull et al. A Novel Multi-Antigen Virally Vectored Vaccine against Mycobacterium avium
JPH11225779A (ja) MurE
WO2012054693A1 (en) Uses of yersinia yope peptide, gene, and subparts thereof as a plague vaccine component and assays for yersinia pestis-specific t cells

Legal Events

Date Code Title Description
RD01 Notification of change of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7426

Effective date: 20210426

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A821

Effective date: 20210426

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220704

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20220704

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230606

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20230817

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20231206

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20240305

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240705

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20240712

A912 Re-examination (zenchi) completed and case transferred to appeal board

Free format text: JAPANESE INTERMEDIATE CODE: A912

Effective date: 20241101