JP2021522825A5 - - Google Patents

Info

Publication number
JP2021522825A5
JP2021522825A5 JP2020563545A JP2020563545A JP2021522825A5 JP 2021522825 A5 JP2021522825 A5 JP 2021522825A5 JP 2020563545 A JP2020563545 A JP 2020563545A JP 2020563545 A JP2020563545 A JP 2020563545A JP 2021522825 A5 JP2021522825 A5 JP 2021522825A5
Authority
JP
Japan
Prior art keywords
domain
vector
isolated polypeptide
nucleic acid
sgrna
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020563545A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021522825A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/CA2019/050629 external-priority patent/WO2019213776A1/en
Publication of JP2021522825A publication Critical patent/JP2021522825A/ja
Publication of JP2021522825A5 publication Critical patent/JP2021522825A5/ja
Pending legal-status Critical Current

Links

JP2020563545A 2018-05-11 2019-05-10 CRISPR/Cas9システムおよびその使用 Pending JP2021522825A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862670135P 2018-05-11 2018-05-11
US62/670,135 2018-05-11
PCT/CA2019/050629 WO2019213776A1 (en) 2018-05-11 2019-05-10 Crispr/cas9 system and uses thereof

Publications (2)

Publication Number Publication Date
JP2021522825A JP2021522825A (ja) 2021-09-02
JP2021522825A5 true JP2021522825A5 (enExample) 2022-05-13

Family

ID=68467641

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020563545A Pending JP2021522825A (ja) 2018-05-11 2019-05-10 CRISPR/Cas9システムおよびその使用

Country Status (4)

Country Link
US (1) US12378549B2 (enExample)
JP (1) JP2021522825A (enExample)
CA (1) CA3101949A1 (enExample)
WO (1) WO2019213776A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024518135A (ja) 2021-05-16 2024-04-24 ジェンエディットバイオ リミテッド 標的化核酸濃縮方法、オフターゲット同定方法及び遺伝子編集効率評価方法
WO2022251181A1 (en) * 2021-05-25 2022-12-01 The Board Of Regents Of The University Of Texas System Correction of duchenne muscular dystrophy mutations with all-in-one adeno-associated virus-delivered single-cut crispr
GB202109675D0 (en) * 2021-07-05 2021-08-18 Ucl Business Ltd Treatment for tyrosine degradation-associated disorders
JP2026523341A (ja) 2023-05-15 2026-07-14 エヌクロマ・バイオ,インコーポレーテッド Hbv遺伝子発現のエピジェネティック調節のための組成物および方法
WO2025194124A1 (en) * 2024-03-14 2025-09-18 Tessera Therapeutics, Inc. Modified st1cas9 guide nucleic acids

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3064585B1 (en) 2012-12-12 2020-02-05 The Broad Institute, Inc. Engineering and optimization of improved systems, methods and enzyme compositions for sequence manipulation
CA2932439A1 (en) * 2013-12-12 2015-06-18 The Broad Institute, Inc. Crispr-cas systems and methods for altering expression of gene products, structural information and inducible modular cas enzymes
JP6793547B2 (ja) * 2013-12-12 2020-12-02 ザ・ブロード・インスティテュート・インコーポレイテッド 最適化機能CRISPR−Cas系による配列操作のための系、方法および組成物
CA2969619A1 (en) 2014-12-03 2016-06-09 Agilent Technologies, Inc. Guide rna with chemical modifications
WO2017070632A2 (en) * 2015-10-23 2017-04-27 President And Fellows Of Harvard College Nucleobase editors and uses thereof

Similar Documents

Publication Publication Date Title
JP2022546608A5 (enExample)
US20220282242A1 (en) Contiguity Preserving Transposition
JP2025170240A5 (enExample)
JP2025181841A5 (enExample)
Lehmann et al. The importance of internal loops within RNA substrates of ADAR1
JP2022545950A5 (enExample)
JP2022520428A5 (enExample)
JP2019536425A5 (enExample)
WO2019042284A1 (en) FUSION PROTEINS FOR ENHANCED PRECISION IN THE BASIC EDITION
EP4227412A1 (en) Engineered guide rna for increasing efficiency of crispr/cas12f1 (cas14a1) system, and use thereof
JP2022521460A5 (enExample)
JP2023545497A5 (enExample)
JP2024511163A5 (enExample)
GB2556276A (en) Engineered crispr-CAS9 compositions and methods of use
JP2025183226A5 (enExample)
JP2024520528A5 (enExample)
JP2024541811A5 (enExample)
RU2022103641A (ru) Искусственная модификация генома для регуляции экспрессии гена
ES2667346T9 (es) Estrategias de secuenciación de región genómica 3-D de interés
JP2024511621A5 (enExample)
JP2023511991A5 (enExample)
JP2022530055A5 (enExample)
JP2022532139A5 (enExample)
JP2021518159A5 (enExample)
JP2025505732A5 (enExample)