|
IL278213B2
(en)
|
2018-04-27 |
2026-04-01 |
Rocket Pharmaceuticals Ltd |
A gene therapy vector encoding an e3 ubiquitin protein ligase (park2) and use thereof in treating or inhibiting the onset of parkinson’s disease (pd)
|
|
US11149256B2
(en)
|
2018-09-26 |
2021-10-19 |
California Institute Of Technology |
Adeno-associated virus compositions for targeted gene therapy
|
|
MX2021005720A
(es)
|
2018-11-16 |
2021-07-21 |
Astellas Pharma Inc |
Metodo para tratar la distrofia muscular mediante el direccionamiento del gen de utrofina.
|
|
CN114450411A
(zh)
|
2019-04-01 |
2022-05-06 |
特纳亚治疗股份有限公司 |
具有工程化衣壳的腺相关病毒
|
|
US20220325296A1
(en)
*
|
2019-09-12 |
2022-10-13 |
The Broad Institute, Inc. |
Engineered adeno-associated virus capsids
|
|
EP4031673A1
(en)
*
|
2019-09-19 |
2022-07-27 |
Genethon |
Gene therapy expression system alleviating cardiac toxicity of fkrp
|
|
TWI897882B
(zh)
*
|
2019-09-20 |
2025-09-21 |
英商Ｕｃｌ商業有限責任公司 |
右心室心律失常性心肌病之基因療法組合物及治療
|
|
IL291944A
(en)
*
|
2019-10-10 |
2022-06-01 |
Solid Biosciences Inc |
Modified aav capsids and uses thereof
|
|
JP2022551986A
(ja)
*
|
2019-10-16 |
2022-12-14 |
ザ・ブロード・インスティテュート・インコーポレイテッド |
修飾筋肉標的化組成物
|
|
CN115379863A
(zh)
|
2020-04-14 |
2022-11-22 |
吉尼松公司 |
用于治疗酸性神经酰胺酶缺乏症的载体
|
|
AU2021259422A1
(en)
|
2020-04-20 |
2022-12-08 |
Tenaya Therapeutics, Inc. |
Adeno-associated virus with engineered capsid
|
|
US20230173102A1
(en)
*
|
2020-04-28 |
2023-06-08 |
Genethon |
Use of a Synthetic AAV Capsid for Gene Therapy of Muscle and Central Nervous System Disorders
|
|
AU2021267885A1
(en)
*
|
2020-05-05 |
2023-01-19 |
Duke University |
Compositions and methods for formation and secretion of extracellular vesicles and AAV particles
|
|
WO2021230385A1
(en)
|
2020-05-15 |
2021-11-18 |
Astellas Pharma Inc. |
Method for treating muscular dystrophy by targeting utrophin gene
|
|
US12668814B2
(en)
*
|
2020-07-22 |
2026-06-30 |
The Broad Institute, Inc. |
Engineered muscle targeting compositions
|
|
WO2022020616A1
(en)
*
|
2020-07-22 |
2022-01-27 |
The Broad Institute, Inc. |
Engineered muscle targeting compositions
|
|
IL300187A
(en)
*
|
2020-08-05 |
2023-03-01 |
Spacecraft Seven Llc |
Gene therapy CSRP3 (protein 3 rich in cysteine and glycine)
|
|
WO2022032226A1
(en)
|
2020-08-07 |
2022-02-10 |
Spacecraft Seven, Llc |
Plakophilin-2 (pkp2) gene therapy using aav vector
|
|
CN116096431A
(zh)
*
|
2020-09-10 |
2023-05-09 |
吉尼松公司 |
肽修饰的aav衣壳
|
|
CN112194706B
(zh)
*
|
2020-09-30 |
2022-03-08 |
广州派真生物技术有限公司 |
腺相关病毒突变体及其应用
|
|
JP7415042B2
(ja)
|
2020-10-09 |
2024-01-16 |
テナヤ セラピューティクス， インコーポレイテッド |
プラコフィリン２遺伝子治療の方法および組成物
|
|
US11781156B2
(en)
|
2020-10-09 |
2023-10-10 |
Tenaya Therapeutics, Inc. |
Plakophillin-2 gene therapy methods and compositions
|
|
MX2023005446A
(es)
|
2020-11-11 |
2023-07-18 |
European Molecular Biology Laboratory |
Particulas virales modificadas para terapia genica.
|
|
WO2022114243A1
(en)
*
|
2020-11-25 |
2022-06-02 |
Astellas Pharma Inc. |
Method for treating muscular dystrophy by targeting dmpk gene
|
|
CA3210955A1
(en)
*
|
2021-02-09 |
2022-08-18 |
Affinia Therapeutics Inc. |
Recombinant aavs with improved tropism and specificity
|
|
CA3216419A1
(en)
*
|
2021-04-23 |
2022-10-27 |
Greg NACHTRAB |
Tissue-targeted modified aav capsids and methods of use thereof
|
|
CN113480615B
(zh)
*
|
2021-07-30 |
2022-05-31 |
上海信致医药科技有限公司 |
高视网膜亲和性的新型腺相关病毒衣壳蛋白及其应用
|
|
CN113563430B
(zh)
*
|
2021-07-30 |
2022-05-31 |
上海信致医药科技有限公司 |
用于治疗眼部疾病的基因递送系统及其应用
|
|
WO2023060113A1
(en)
|
2021-10-05 |
2023-04-13 |
Regenxbio Inc. |
Compositions and methods for recombinant aav production
|
|
CN118202060A
(zh)
|
2021-10-05 |
2024-06-14 |
再生生物股份有限公司 |
用于重组aav生产的组合物和方法
|
|
KR20240095539A
(ko)
|
2021-10-08 |
2024-06-25 |
디노 테라퓨틱스, 인코포레이티드 |
캡시드 변이체 및 이의 사용 방법
|
|
EP4453013A1
(en)
*
|
2021-12-21 |
2024-10-30 |
Research Institute at Nationwide Children's Hospital |
Materials and methods for the treatment of limb girdle muscular dystrophy
|
|
CN114516901B
(zh)
*
|
2022-03-11 |
2023-01-17 |
上海勉亦生物科技有限公司 |
一种神经系统高亲和性的aav载体及其应用
|
|
US20250195694A1
(en)
*
|
2022-03-18 |
2025-06-19 |
University Of Florida Research Foundation, Incorporated |
Methods and compositions for treating tnnt2 related cardiomyopathy with a viral vector
|
|
KR20240169111A
(ko)
|
2022-04-06 |
2024-12-02 |
젠자임 코포레이션 |
Dm-1 근긴장성 이영양증에 대한 표적화된 유전자 요법
|
|
EP4507719A1
(en)
|
2022-04-13 |
2025-02-19 |
Universitat Autònoma de Barcelona |
Treatment of neuromuscular diseases via gene therapy that expresses klotho protein
|
|
EP4269426A1
(en)
*
|
2022-04-29 |
2023-11-01 |
Ospedale San Raffaele S.r.l. |
Gene therapy
|
|
FI4536686T3
(fi)
|
2022-06-10 |
2026-01-13 |
Genethon |
Lihaksen parannetun transduktiotehokkuuden omaava peptidimodifioitu aav-kapsidi
|
|
JP2026509271A
(ja)
|
2023-03-10 |
2026-03-17 |
ダイノ セラピューティクス，インコーポレーテッド |
カプシドポリペプチドおよびその使用方法
|
|
WO2024188913A1
(en)
|
2023-03-10 |
2024-09-19 |
Genethon |
Induction of immune tolerance by aav vector comprising the combination of a liver detargeted capsid and a tandem liver-muscle specific promoter
|
|
WO2024192281A2
(en)
|
2023-03-15 |
2024-09-19 |
Regenxbio Inc. |
Exon skipping gene therapy constructs, vectors and uses thereof
|
|
WO2024211480A2
(en)
|
2023-04-05 |
2024-10-10 |
Genzyme Corporation |
Targeted gene therapy for dm-1 myotonic dystrophy
|
|
AU2024271851A1
(en)
|
2023-05-16 |
2025-12-18 |
Affinia Therapeutics Inc. |
Recombinant aavs with improved tropism and specificity
|
|
CN121712809A
(zh)
|
2023-07-03 |
2026-03-20 |
Ucb生物制药有限责任公司 |
工程化的aav衣壳蛋白
|
|
CN117964715B
(zh)
*
|
2023-07-21 |
2025-01-24 |
广州派真生物技术有限公司 |
腺相关病毒突变体及其应用
|
|
KR20260082361A
(ko)
|
2023-08-31 |
2026-06-04 |
디노 테라퓨틱스, 인코포레이티드 |
캡시드 폴리펩타이드 및 이의 사용 방법
|
|
WO2025133247A1
(en)
|
2023-12-21 |
2025-06-26 |
Genethon |
Methods for aav vector re-administration
|
|
TW202545971A
(zh)
|
2024-02-08 |
2025-12-01 |
美商戴諾治療公司 |
殼體多肽及其使用方法
|
|
WO2025232917A1
(en)
*
|
2024-05-10 |
2025-11-13 |
Hangzhou Jiayin Biotech Ltd. |
Novel liver detargeted aav variants and uses thereof
|
|
WO2026006341A1
(en)
|
2024-06-24 |
2026-01-02 |
Regenxbio Inc. |
Microdystrophin gene therapy administration for treatment of dystrophinopathies
|
|
WO2026017727A1
(en)
|
2024-07-16 |
2026-01-22 |
Genethon |
Alternative barcoding method to assess transduction efficiency of aav vectors
|
|
WO2026064444A1
(en)
|
2024-09-18 |
2026-03-26 |
Dyno Therapeutics, Inc. |
Capsid polypeptides and methods of use thereof
|
|
WO2026064428A2
(en)
|
2024-09-18 |
2026-03-26 |
Dyno Therapeutics, Inc. |
Capsid polypeptides and methods of use thereof
|
|
WO2026064442A2
(en)
|
2024-09-18 |
2026-03-26 |
Dyno Therapeutics, Inc. |
Capsid polypeptides and methods of use thereof
|
|
WO2026094009A1
(en)
|
2024-11-04 |
2026-05-07 |
Insmed Incorporated |
Compositions and methods for treating duchenne muscular dystrophy
|
|
WO2026122963A1
(en)
|
2024-12-06 |
2026-06-11 |
Dyno Therapeutics, Inc. |
Capsid polypeptides and methods of use thereof
|