JP2021521777A5 - - Google Patents

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Publication number
JP2021521777A5
JP2021521777A5 JP2020556877A JP2020556877A JP2021521777A5 JP 2021521777 A5 JP2021521777 A5 JP 2021521777A5 JP 2020556877 A JP2020556877 A JP 2020556877A JP 2020556877 A JP2020556877 A JP 2020556877A JP 2021521777 A5 JP2021521777 A5 JP 2021521777A5
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JP
Japan
Prior art keywords
cell
enzyme
transgenic
cells
composition
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Application number
JP2020556877A
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English (en)
Japanese (ja)
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JP7432851B2 (ja
JP2021521777A (ja
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Priority claimed from PCT/US2019/027623 external-priority patent/WO2019204269A1/en
Publication of JP2021521777A publication Critical patent/JP2021521777A/ja
Publication of JP2021521777A5 publication Critical patent/JP2021521777A5/ja
Application granted granted Critical
Publication of JP7432851B2 publication Critical patent/JP7432851B2/ja
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JP2020556877A 2018-04-16 2019-04-16 ヒトキヌレニナーゼ酵素及びその使用 Active JP7432851B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862658261P 2018-04-16 2018-04-16
US62/658,261 2018-04-16
PCT/US2019/027623 WO2019204269A1 (en) 2018-04-16 2019-04-16 Human kynureninase enzymes and uses thereof

Publications (3)

Publication Number Publication Date
JP2021521777A JP2021521777A (ja) 2021-08-30
JP2021521777A5 true JP2021521777A5 (enExample) 2022-04-07
JP7432851B2 JP7432851B2 (ja) 2024-02-19

Family

ID=68240288

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020556877A Active JP7432851B2 (ja) 2018-04-16 2019-04-16 ヒトキヌレニナーゼ酵素及びその使用

Country Status (18)

Country Link
US (2) US11648272B2 (enExample)
EP (1) EP3781179A4 (enExample)
JP (1) JP7432851B2 (enExample)
KR (1) KR102862473B1 (enExample)
CN (1) CN112218644A (enExample)
AR (1) AR115051A1 (enExample)
AU (1) AU2019257340B2 (enExample)
BR (1) BR112020020772A2 (enExample)
CA (1) CA3096549A1 (enExample)
CL (1) CL2020002650A1 (enExample)
CO (1) CO2020013050A2 (enExample)
EA (1) EA202092487A1 (enExample)
IL (1) IL277765B1 (enExample)
MX (1) MX2020010932A (enExample)
SG (1) SG11202009559RA (enExample)
TW (1) TWI827593B (enExample)
WO (1) WO2019204269A1 (enExample)
ZA (1) ZA202006077B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102271498B1 (ko) 2013-08-30 2021-07-05 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 종양 치료를 위한 키누레닌 고갈 효소의 투여
EP3186371B1 (en) * 2014-08-29 2024-08-14 Board of Regents, The University of Texas System Administration of kynurenine depleting enzymes for tumor therapy
EP3423483B1 (en) 2016-03-02 2025-09-24 Board Of Regents Of the University Of Texas System Human kynureninase enzyme variants having improved pharmacological properties
CN114828863A (zh) * 2019-10-17 2022-07-29 医肯纳肿瘤学公司 聚乙二醇化犬尿氨酸酶以及其用于治疗癌症的用途
WO2024085280A1 (ko) * 2022-10-20 2024-04-25 서울대학교 산학협력단 신규한 키뉴레니나제 및 이의 용도

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030194721A1 (en) 2001-09-19 2003-10-16 Incyte Genomics, Inc. Genes expressed in treated foam cells
JP2005516605A (ja) 2002-02-01 2005-06-09 ミレニアム・ファーマシューティカルズ・インコーポレイテッド 心血管疾患を処置するための方法および組成物
CN1330774C (zh) 2002-03-01 2007-08-08 国家人类基因组南方研究中心 犬尿氨酸水解酶多态性及其用途
US7714139B2 (en) 2003-03-27 2010-05-11 Lankenau Institute For Medcial Research IDO inhibitors and methods of use
US20070207158A1 (en) 2003-06-17 2007-09-06 Harrison Roger G Conjugate for the specific targeting of anticancer agents to tumor cells or tumor vasculature and production thereof
CA2534639C (en) 2003-07-31 2013-07-30 Immunomedics, Inc. Anti-cd19 antibodies
JP2008237022A (ja) 2005-06-30 2008-10-09 Osaka Prefecture 非小細胞肺がんの予防・治療剤および診断薬
WO2008036642A2 (en) 2006-09-19 2008-03-27 Incyte Corporation N-hydroxyamidinoheterocycles as modulators of indoleamine 2,3-dioxygenase
CA2776143A1 (en) 2009-10-01 2011-04-07 The United States Of America, As Represented By The Secretary, Departmen T Of Health And Human Services Anti-vascular endothelial growth factor receptor-2 chimeric antigen receptors and use of same for the treatment of cancer
ES2602743T3 (es) 2010-09-08 2017-02-22 Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus Receptores de antígenos quiméricos con una región bisagra optimizada
PH12013501201A1 (en) 2010-12-09 2013-07-29 Univ Pennsylvania Use of chimeric antigen receptor-modified t cells to treat cancer
WO2012099441A2 (ko) 2011-01-21 2012-07-26 인제대학교산학협력단 트립토판 대사효소 유전자를 발현하는 줄기세포를 함유하는 면역 반응 억제용 조성물
KR20120085209A (ko) 2011-01-21 2012-07-31 인제대학교 산학협력단 트립토판 대사효소 유전자를 발현하는 줄기세포를 함유하는 면역 반응 억제용 조성물
US9593062B2 (en) 2011-09-07 2017-03-14 Deutschland Krebsforschungszentrum Means and methods for treating and/or preventing natural AHR ligand-dependent cancer
ES2654060T3 (es) 2011-10-20 2018-02-12 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Receptores de antígenos quiméricos anti-CD22
KR102271498B1 (ko) 2013-08-30 2021-07-05 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 종양 치료를 위한 키누레닌 고갈 효소의 투여
EP3186371B1 (en) * 2014-08-29 2024-08-14 Board of Regents, The University of Texas System Administration of kynurenine depleting enzymes for tumor therapy
EP3423483B1 (en) 2016-03-02 2025-09-24 Board Of Regents Of the University Of Texas System Human kynureninase enzyme variants having improved pharmacological properties

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