JP2021521274A5 - - Google Patents

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Publication number
JP2021521274A5
JP2021521274A5 JP2021504589A JP2021504589A JP2021521274A5 JP 2021521274 A5 JP2021521274 A5 JP 2021521274A5 JP 2021504589 A JP2021504589 A JP 2021504589A JP 2021504589 A JP2021504589 A JP 2021504589A JP 2021521274 A5 JP2021521274 A5 JP 2021521274A5
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JP
Japan
Prior art keywords
pdl
cancer
pharmaceutical composition
composition according
amino acid
Prior art date
Application number
JP2021504589A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2019197903A5 (https=
JP7423598B2 (ja
JP2021521274A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/IB2019/000423 external-priority patent/WO2019197903A1/en
Publication of JP2021521274A publication Critical patent/JP2021521274A/ja
Publication of JPWO2019197903A5 publication Critical patent/JPWO2019197903A5/ja
Publication of JP2021521274A5 publication Critical patent/JP2021521274A5/ja
Priority to JP2024005463A priority Critical patent/JP2024054138A/ja
Application granted granted Critical
Publication of JP7423598B2 publication Critical patent/JP7423598B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2021504589A 2018-04-12 2019-04-11 がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ Active JP7423598B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024005463A JP2024054138A (ja) 2018-04-12 2024-01-17 がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP18382248.5 2018-04-12
EP18382248 2018-04-12
EP18382326 2018-05-14
EP18382326.9 2018-05-14
EP18382360 2018-05-25
EP18382360.8 2018-05-25
EP19382132.9 2019-02-22
EP19382132 2019-02-22
PCT/IB2019/000423 WO2019197903A1 (en) 2018-04-12 2019-04-11 Combination of lif inhibitors and pd-1 axis inhibitors for use in treating cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024005463A Division JP2024054138A (ja) 2018-04-12 2024-01-17 がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ

Publications (4)

Publication Number Publication Date
JP2021521274A JP2021521274A (ja) 2021-08-26
JPWO2019197903A5 JPWO2019197903A5 (https=) 2022-04-18
JP2021521274A5 true JP2021521274A5 (https=) 2022-04-18
JP7423598B2 JP7423598B2 (ja) 2024-01-29

Family

ID=67060425

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021504589A Active JP7423598B2 (ja) 2018-04-12 2019-04-11 がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ
JP2024005463A Ceased JP2024054138A (ja) 2018-04-12 2024-01-17 がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024005463A Ceased JP2024054138A (ja) 2018-04-12 2024-01-17 がんの治療で使用するためのｌｉｆ阻害剤とｐｄ－１軸阻害剤との組み合わせ

Country Status (11)

Country Link
US (1) US20210130453A1 (https=)
EP (1) EP3774895A1 (https=)
JP (2) JP7423598B2 (https=)
KR (1) KR20210021287A (https=)
CN (1) CN112585164A (https=)
AU (1) AU2019251289B2 (https=)
CA (1) CA3096779A1 (https=)
IL (1) IL277918A (https=)
MA (1) MA52231A (https=)
SG (1) SG11202009966SA (https=)
WO (1) WO2019197903A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3555132B1 (en) * 2016-12-19 2023-11-15 Medimmune Limited Antibodies against lif and uses thereof
AU2019269131B2 (en) * 2018-05-14 2024-02-22 Fundació Privada Institució Catalana De Recerca I Estudis Avançats Antibodies against LIF and dosage forms thereof
EP4069736A1 (en) * 2019-12-04 2022-10-12 MedImmune Limited Antibodies against lif and uses thereof
WO2021183370A1 (en) * 2020-03-11 2021-09-16 Purdue Research Foundation Compounds with immunomodulatory activity and therapeutic uses thereof
WO2023159152A2 (en) * 2022-02-17 2023-08-24 Immune-Onc Therapeutics, Inc. Combination therapy of lilrb antagonist and pd-1/pd-l1 axis inhibitor

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL85035A0 (en) 1987-01-08 1988-06-30 Int Genetic Eng Polynucleotide molecule,a chimeric antibody with specificity for human b cell surface antigen,a process for the preparation and methods utilizing the same
WO1988007089A1 (en) 1987-03-18 1988-09-22 Medical Research Council Altered antibodies
EP1400536A1 (en) 1991-06-14 2004-03-24 Genentech Inc. Method for making humanized antibodies
AU4231393A (en) * 1992-05-08 1993-12-13 Genentech Inc. Antibodies to leukemia inhibitory factor
AU691811B2 (en) 1993-06-16 1998-05-28 Celltech Therapeutics Limited Antibodies
HU230769B1 (hu) 1999-01-15 2018-03-28 Genentech Inc. Módosított effektor-funkciójú polipeptid-változatok
US7361740B2 (en) 2002-10-15 2008-04-22 Pdl Biopharma, Inc. Alteration of FcRn binding affinities or serum half-lives of antibodies by mutagenesis
EP2371860A1 (en) * 2010-04-05 2011-10-05 Fundació Privada Institut d'Investigació Oncològica de Vall d'Hebron Antibody recognising human leukemia inhibitory factor (LIF) and use of anti-LIF antibodies in the treatment of diseases associated with unwanted cell proliferation
CN106687134A (zh) * 2014-09-10 2017-05-17 加利福尼亚大学董事会 通过抗hLIF抗体靶向K‑RAS介导的信号转导通路和恶性肿瘤
EP3173483A1 (en) * 2015-11-27 2017-05-31 Fundació Privada Institut d'Investigació Oncològica de Vall-Hebron Agents for the treatment of diseases associated with undesired cell proliferation
US10583191B2 (en) * 2016-12-19 2020-03-10 Mosaic Biomedicals Slu Antibodies against LIF and uses thereof
EP3555132B1 (en) * 2016-12-19 2023-11-15 Medimmune Limited Antibodies against lif and uses thereof

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