JP2021521230A5 - - Google Patents
Info
- Publication number
- JP2021521230A5 JP2021521230A5 JP2020556885A JP2020556885A JP2021521230A5 JP 2021521230 A5 JP2021521230 A5 JP 2021521230A5 JP 2020556885 A JP2020556885 A JP 2020556885A JP 2020556885 A JP2020556885 A JP 2020556885A JP 2021521230 A5 JP2021521230 A5 JP 2021521230A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- insulin
- chain
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862658372P | 2018-04-16 | 2018-04-16 | |
| US62/658,372 | 2018-04-16 | ||
| PCT/US2019/027484 WO2019204206A1 (en) | 2018-04-16 | 2019-04-15 | Glucose-responsive insulin |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021521230A JP2021521230A (ja) | 2021-08-26 |
| JP2021521230A5 true JP2021521230A5 (enExample) | 2022-04-25 |
Family
ID=68239869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020556885A Pending JP2021521230A (ja) | 2018-04-16 | 2019-04-15 | グルコース応答性インスリン |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20210214412A1 (enExample) |
| EP (1) | EP3781147A4 (enExample) |
| JP (1) | JP2021521230A (enExample) |
| KR (1) | KR20210005630A (enExample) |
| CN (1) | CN112423741A (enExample) |
| AU (1) | AU2019255611A1 (enExample) |
| CA (1) | CA3097359A1 (enExample) |
| WO (1) | WO2019204206A1 (enExample) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3291828A4 (en) | 2015-05-06 | 2018-10-03 | Alborz Mahdavi | Glucose responsive insulins |
| WO2018107117A1 (en) | 2016-12-09 | 2018-06-14 | Akston Biosciences Corporation | Insulin-fc fusions and methods of use |
| EP3707145B1 (en) | 2017-11-09 | 2023-06-21 | Novo Nordisk A/S | Glucose-sensitive albumin-binding derivatives |
| CN113038964B (zh) | 2018-06-29 | 2025-05-27 | 德克拉有限公司 | 超长效胰岛素-fc融合蛋白及使用方法 |
| US11267862B2 (en) | 2018-06-29 | 2022-03-08 | Akston Biosciences Corporation | Ultra-long acting insulin-Fc fusion proteins and methods of use |
| JP7640462B2 (ja) * | 2019-03-29 | 2025-03-05 | ノヴォ ノルディスク アー／エス | グルコース感受性インスリン誘導体 |
| US20220288213A1 (en) * | 2019-07-31 | 2022-09-15 | Thermalin Inc. | Insulin analogues with glucose regulated conformational switch |
| HUE064376T2 (hu) | 2019-12-19 | 2024-03-28 | Akston Biosciences Corp | Ultra-hosszú hatású inzulin-FC fúziós fehérjék és felhasználási eljárások |
| US11186623B2 (en) | 2019-12-24 | 2021-11-30 | Akston Bioscience Corporation | Ultra-long acting insulin-Fc fusion proteins and methods of use |
| CA3173417A1 (en) * | 2020-03-31 | 2021-10-07 | Alborz Mahdavi | Conjugates for selective responsiveness to vicinal diols |
| US11192930B2 (en) | 2020-04-10 | 2021-12-07 | Askton Bioscences Corporation | Ultra-long acting insulin-Fc fusion protein and methods of use |
| KR102898622B1 (ko) | 2020-04-10 | 2025-12-12 | 악스톤 바이오사이언시스 코퍼레이션 | Covid-19 융합 단백질에 대한 항원 특이적 면역요법 및 사용 방법 |
| US11198719B2 (en) | 2020-04-29 | 2021-12-14 | Akston Biosciences Corporation | Ultra-long acting insulin-Fc fusion protein and methods of use |
| PH12023500012A1 (en) * | 2020-11-19 | 2024-03-11 | Protomer Tech Inc | Aromatic boron-containing compounds and insulin analogs |
| WO2023004406A2 (en) | 2021-07-23 | 2023-01-26 | Akston Biosciences Corporation | Insulin-fc fusion proteins and methods of use to treat cancer |
| CN119136821A (zh) * | 2022-02-17 | 2024-12-13 | 雷沃洛生物医疗有限公司 | 产生衍生自伴侣蛋白60.1的肽的方法 |
| WO2023225534A1 (en) | 2022-05-18 | 2023-11-23 | Protomer Technologies Inc. | Aromatic boron-containing compounds and related insulin analogs |
| WO2025117822A1 (en) * | 2023-11-28 | 2025-06-05 | University Of Notre Dame Du Lac | Glucose-triggered gelation of supramolecular peptide nanocoils with glucose-binding motifs |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6070100A (ja) * | 1983-09-26 | 1985-04-20 | Wako Pure Chem Ind Ltd | 新規ヒト型インシュリン誘導体，その製法，及びヒト型インシュリンの製造法 |
| DE3837825A1 (de) * | 1988-11-08 | 1990-05-10 | Hoechst Ag | Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung |
| JP2005526009A (ja) * | 2001-12-02 | 2005-09-02 | ノボ ノルディスク アクティーゼルスカブ | 新規グルコース依存性インスリン |
| US7317000B2 (en) * | 2001-12-02 | 2008-01-08 | Novo Nordisk A/S | Glucose-dependent insulins |
| US7928186B2 (en) * | 2006-08-02 | 2011-04-19 | Phoenix Pharmaceuticals, Inc. | Cell permeable bioactive peptide conjugates |
| WO2011103575A1 (en) * | 2010-02-22 | 2011-08-25 | Case Western Reserve University | Long-acting insulin analogue preparations in soluble and crystalline forms |
| UA113626C2 (xx) * | 2011-06-02 | 2017-02-27 | Композиція для лікування діабету, що містить кон'югат інсуліну тривалої дії та кон'югат інсулінотропного пептиду тривалої дії | |
| US20160031962A1 (en) * | 2012-04-20 | 2016-02-04 | Kleomenis K. Barlos | Solid phase peptide synthesis of insulin using side chain achored lysine |
| WO2014093696A2 (en) * | 2012-12-12 | 2014-06-19 | Massachusetts Institute Of Technology | Insulin derivatives for diabetes treatment |
| EP3291828A4 (en) * | 2015-05-06 | 2018-10-03 | Alborz Mahdavi | Glucose responsive insulins |
-
2019
- 2019-04-15 AU AU2019255611A patent/AU2019255611A1/en not_active Abandoned
- 2019-04-15 US US17/040,973 patent/US20210214412A1/en not_active Abandoned
- 2019-04-15 CA CA3097359A patent/CA3097359A1/en active Pending
- 2019-04-15 JP JP2020556885A patent/JP2021521230A/ja active Pending
- 2019-04-15 CN CN201980031925.3A patent/CN112423741A/zh active Pending
- 2019-04-15 EP EP19789533.7A patent/EP3781147A4/en not_active Withdrawn
- 2019-04-15 WO PCT/US2019/027484 patent/WO2019204206A1/en not_active Ceased
- 2019-04-15 KR KR1020207032777A patent/KR20210005630A/ko not_active Ceased
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