JP2021520394A5 - - Google Patents

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Publication number
JP2021520394A5
JP2021520394A5 JP2020555045A JP2020555045A JP2021520394A5 JP 2021520394 A5 JP2021520394 A5 JP 2021520394A5 JP 2020555045 A JP2020555045 A JP 2020555045A JP 2020555045 A JP2020555045 A JP 2020555045A JP 2021520394 A5 JP2021520394 A5 JP 2021520394A5
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JP
Japan
Prior art keywords
alkyl
group
heterocyclyl
pharmaceutical composition
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020555045A
Other languages
English (en)
Japanese (ja)
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JP2021520394A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2019/059341 external-priority patent/WO2019201752A1/en
Publication of JP2021520394A publication Critical patent/JP2021520394A/ja
Publication of JP2021520394A5 publication Critical patent/JP2021520394A5/ja
Pending legal-status Critical Current

Links

JP2020555045A 2018-04-17 2019-04-11 医薬組成物、処置方法及びその使用 Pending JP2021520394A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18167739.4 2018-04-17
EP18167739 2018-04-17
PCT/EP2019/059341 WO2019201752A1 (en) 2018-04-17 2019-04-11 Pharmaceutical composition, methods for treating and uses thereof

Publications (2)

Publication Number Publication Date
JP2021520394A JP2021520394A (ja) 2021-08-19
JP2021520394A5 true JP2021520394A5 (OSRAM) 2022-04-12

Family

ID=62017227

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020555045A Pending JP2021520394A (ja) 2018-04-17 2019-04-11 医薬組成物、処置方法及びその使用

Country Status (6)

Country Link
US (1) US20210113561A1 (OSRAM)
EP (1) EP3781166A1 (OSRAM)
JP (1) JP2021520394A (OSRAM)
CN (1) CN111989103A (OSRAM)
AU (1) AU2019254371A1 (OSRAM)
WO (1) WO2019201752A1 (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020089025A1 (en) 2018-10-29 2020-05-07 Boehringer Ingelheim International Gmbh Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof
SG11202102440SA (en) 2018-10-29 2021-04-29 Boehringer Ingelheim Int Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof
CN113893256A (zh) * 2020-07-06 2022-01-07 诺未科技(北京)有限公司 化合物或其可药用盐、二聚体或三聚体在制备治疗癌症的药物中的应用
CN120983424B (zh) * 2025-09-09 2026-04-28 齐鲁工业大学(山东省科学院) (R)-8-hydroxy-3,5,7-trimethylisochroman-1-one在制备抗扩张型心肌病药中的应用

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA71994C2 (en) 1999-08-31 2005-01-17 Kissei Pharmaceutical Glucopyranosyloxypyrazole derivatives, a pharmaceutical composition containing these derivatives and intermediate compounds for the preparation thereof
US6515117B2 (en) 1999-10-12 2003-02-04 Bristol-Myers Squibb Company C-aryl glucoside SGLT2 inhibitors and method
PH12000002657B1 (en) 1999-10-12 2006-02-21 Bristol Myers Squibb Co C-aryl glucoside SGLT2 inhibitors
AU2002223127A1 (en) 2000-11-30 2002-06-11 Kissei Pharmaceutical Co., Ltd. Intellectual Property Glucopyranosyloxybenzyl benzene derivatives, medicinal compositions containing the same and intermediates in the production thereof
SI1354888T1 (sl) 2000-12-28 2009-10-31 Kissei Pharmaceutical Glukopiranoziloksipirazolni derivati in njihova uporaba v zdravilih
BR0308653A (pt) 2002-03-22 2005-02-15 Kissei Pharmaceutical Cristais de derivado de benzeno de glicopiranosiloxibenzila
DE10231370B4 (de) 2002-07-11 2006-04-06 Sanofi-Aventis Deutschland Gmbh Thiophenglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
CN1802366B (zh) 2003-03-14 2010-12-22 安斯泰来制药有限公司 C-糖苷衍生物及其盐
MXPA06001274A (es) 2003-08-01 2006-04-11 Tanabe Seiyaku Co Compuestos novedosos que poseen actividad inhibitoria contra transporador dependiente de sodio.
EP2360165A3 (de) 2004-03-16 2012-01-04 Boehringer Ingelheim International GmbH Glucopyranosyl-substituierte Benzol-Derivate, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
TW200637839A (en) 2005-01-07 2006-11-01 Taisho Pharmaceutical Co Ltd 1-thio-d-glucitol derivatives
TW200637869A (en) 2005-01-28 2006-11-01 Chugai Pharmaceutical Co Ltd The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
UA91546C2 (uk) 2005-05-03 2010-08-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ
US7772191B2 (en) 2005-05-10 2010-08-10 Boehringer Ingelheim International Gmbh Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
AU2007216452A1 (en) 2006-02-15 2007-08-23 Boehringer Ingelheim International Gmbh Glucopyranosyl-substituted benzonitrile derivatives, pharmaceutical compositions containing such compounds, their use and process for their manufacture
US7803778B2 (en) 2006-05-23 2010-09-28 Theracos, Inc. Glucose transport inhibitors and methods of use
US7919598B2 (en) 2006-06-28 2011-04-05 Bristol-Myers Squibb Company Crystal structures of SGLT2 inhibitors and processes for preparing same
TWI499414B (zh) 2006-09-29 2015-09-11 Lexicon Pharmaceuticals Inc 鈉與葡萄糖第2型共同運輸體(co-transporter 2)的抑制物與其應用方法
UY30730A1 (es) 2006-12-04 2008-07-03 Mitsubishi Tanabe Pharma Corp Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
US7846945B2 (en) 2007-03-08 2010-12-07 Lexicon Pharmaceuticals, Inc. Piperdine-based inhibitors of sodium glucose co-transporter 2 and methods of their use
AR065809A1 (es) 2007-03-22 2009-07-01 Bristol Myers Squibb Co Formulaciones farmaceuticas que contienen un inhibidor sglt2
ES2375800T3 (es) 2007-07-26 2012-03-06 Lexicon Pharmaceuticals, Inc. Métodos y compuestos útiles para la preparación de inhibidores de cotransportador 2 de sódio-glucosa.
CN101801371B (zh) 2007-09-10 2012-11-28 詹森药业有限公司 可用作sglt抑制剂的化合物的制备方法
TW201011043A (en) 2008-06-20 2010-03-16 Chugai Pharmaceutical Co Ltd Crystal of spiroketal derivatives and process for preparation of spiroketal derivatives
TWI472521B (zh) 2008-07-17 2015-02-11 Lexicon Pharmaceuticals Inc (2s,3r,4r,5s,6r)-2-(4-氯-3-(4-乙氧苄基)苯基)-6-(甲硫)四氫-2h-哌喃-3,4,5-三醇的固體形態與其使用方法
MX2011002166A (es) 2008-08-28 2011-04-07 Pfizer Derivados de dioxa-biciclo[3.2.1]octano-2,3,1-triol.
MX345494B (es) 2009-02-13 2017-02-02 Boehringer Ingelheim Int Gmbh * Composición farmacéutica que comprende derivados de glucopiranosil difenilmetano, dosificación farmacéutica de la misma, procesos para su preparación y usos de la misma para el control glucemico mejorado en un paciente.
MY161472A (en) * 2009-02-13 2017-04-14 Boehringer Ingelheim Int Sglt-2 inhibitor for treating type 1 diabetes mellitus, type 2 diabetes mellitus, impaired glucose tolerance or hyperglycemia
PL2395983T3 (pl) * 2009-02-13 2020-09-07 Boehringer Ingelheim International Gmbh Kompozycja farmaceutyczna zawierająca inhibitor sglt2, inhibitor dpp-iv i ewentualnie dalszy środek przeciwcukrzycowy oraz jej zastosowania
PL2419097T3 (pl) 2009-04-16 2014-02-28 Taisho Pharmaceutical Co Ltd Kompozycja farmaceutyczna zawierająca (1S)-1,5-anhydro-1-[5-(4-etoksybenzylo)-2-metoksy-4-metylofenylo]-1-tio-D-glucitol i metforminę oraz jej zastosowanie w leczeniu cukrzycy
BR112012007085B8 (pt) 2009-09-30 2021-05-25 Boehringer Ingelheim Int processos para a preparação de derivados de benzil-benzeno substituídos com glicopiranosila
HUE029381T2 (en) 2009-09-30 2017-02-28 Boehringer Ingelheim Int Method for the preparation of a crystalline form of 1-chloro-4-(beta-d-glucopyranos-1-yl)-2-(4-((s)-tetrahydrofuran-3-yloxy)benzyl)benzene
WO2014123749A1 (en) * 2013-01-30 2014-08-14 Board Of Regents Of The University Of Nebraska Compositions and methods for treating complications associated with diabetes
US20180021341A1 (en) * 2015-01-09 2018-01-25 Gilead Apollo, Llc Acc inhibitor combination therapy for the treatment of non-alcoholic fatty liver disease
EP3455216B1 (en) * 2016-05-12 2020-11-04 Boehringer Ingelheim International GmbH Pyridinyl derivatives, pharmaceutical compositions and uses thereof as aoc3 inhibitors

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