JP2021519797A5 - - Google Patents

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Publication number
JP2021519797A5
JP2021519797A5 JP2020553610A JP2020553610A JP2021519797A5 JP 2021519797 A5 JP2021519797 A5 JP 2021519797A5 JP 2020553610 A JP2020553610 A JP 2020553610A JP 2020553610 A JP2020553610 A JP 2020553610A JP 2021519797 A5 JP2021519797 A5 JP 2021519797A5
Authority
JP
Japan
Prior art keywords
pgdh inhibitor
renal
inhibitor according
ch2x
ischemia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2020553610A
Other languages
English (en)
Japanese (ja)
Other versions
JP7426941B2 (ja
JP2021519797A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/025812 external-priority patent/WO2019195565A1/en
Publication of JP2021519797A publication Critical patent/JP2021519797A/ja
Publication of JP2021519797A5 publication Critical patent/JP2021519797A5/ja
Application granted granted Critical
Publication of JP7426941B2 publication Critical patent/JP7426941B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2020553610A 2018-04-04 2019-04-04 腎傷害を治療するための組成物および方法 Active JP7426941B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862652769P 2018-04-04 2018-04-04
US62/652,769 2018-04-04
PCT/US2019/025812 WO2019195565A1 (en) 2018-04-04 2019-04-04 Compositions and methods for treating renal injury

Publications (3)

Publication Number Publication Date
JP2021519797A JP2021519797A (ja) 2021-08-12
JP2021519797A5 true JP2021519797A5 (https=) 2022-04-07
JP7426941B2 JP7426941B2 (ja) 2024-02-02

Family

ID=68101395

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020553610A Active JP7426941B2 (ja) 2018-04-04 2019-04-04 腎傷害を治療するための組成物および方法

Country Status (7)

Country Link
US (3) US20210100779A1 (https=)
EP (1) EP3781154A4 (https=)
JP (1) JP7426941B2 (https=)
CN (1) CN112739344A (https=)
AU (2) AU2019247838A1 (https=)
CA (1) CA3095308A1 (https=)
WO (1) WO2019195565A1 (https=)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11690847B2 (en) 2016-11-30 2023-07-04 Case Western Reserve University Combinations of 15-PGDH inhibitors with corticosteroids and/or TNF inhibitors and uses thereof
US11718589B2 (en) 2017-02-06 2023-08-08 Case Western Reserve University Compositions and methods of modulating short-chain dehydrogenase
US12336982B2 (en) 2018-11-21 2025-06-24 Rodeo Therapeutics Corporation Compositions and methods of modulating short-chain dehydrogenase activity
US12616681B2 (en) 2022-08-22 2026-05-05 Case Western Reserve University Compositions and methods for treating renal injury

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023515081A (ja) * 2020-02-21 2023-04-12 ケース ウエスタン リザーブ ユニバーシティ 腎損傷を治療するための組成物および方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050187221A1 (en) * 2003-09-08 2005-08-25 Japan Tobacco Inc. Method of treating ischemia reperfusion injury
DK2838533T3 (da) * 2012-04-16 2017-11-27 Univ Case Western Reserve Sammensætninger og fremgangsmåder til at modulere 15-pgdh-aktivitet
AU2014342811B2 (en) 2013-10-15 2019-01-03 Board Of Regents Of The University Of Texas System Compositions and methods of modulating short-chain dehydrogenase activity
AU2016248080A1 (en) * 2015-04-14 2017-11-02 Board Of Regents Of The University Of Texas System Compositions and methods of modulating short-chain dehydrogenase activity

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11690847B2 (en) 2016-11-30 2023-07-04 Case Western Reserve University Combinations of 15-PGDH inhibitors with corticosteroids and/or TNF inhibitors and uses thereof
US11718589B2 (en) 2017-02-06 2023-08-08 Case Western Reserve University Compositions and methods of modulating short-chain dehydrogenase
US12336982B2 (en) 2018-11-21 2025-06-24 Rodeo Therapeutics Corporation Compositions and methods of modulating short-chain dehydrogenase activity
US12616681B2 (en) 2022-08-22 2026-05-05 Case Western Reserve University Compositions and methods for treating renal injury

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