JP2008285464A5 - - Google Patents

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Publication number
JP2008285464A5
JP2008285464A5 JP2007175769A JP2007175769A JP2008285464A5 JP 2008285464 A5 JP2008285464 A5 JP 2008285464A5 JP 2007175769 A JP2007175769 A JP 2007175769A JP 2007175769 A JP2007175769 A JP 2007175769A JP 2008285464 A5 JP2008285464 A5 JP 2008285464A5
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JP
Japan
Prior art keywords
group
chlorophenyl
alkyl
carbamoyl
substituted
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Granted
Application number
JP2007175769A
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English (en)
Japanese (ja)
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JP2008285464A (ja
JP4846665B2 (ja
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Priority to JP2007175769A priority Critical patent/JP4846665B2/ja
Priority claimed from JP2007175769A external-priority patent/JP4846665B2/ja
Publication of JP2008285464A publication Critical patent/JP2008285464A/ja
Publication of JP2008285464A5 publication Critical patent/JP2008285464A5/ja
Application granted granted Critical
Publication of JP4846665B2 publication Critical patent/JP4846665B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2007175769A 2006-07-05 2007-07-04 ピラゾロ［１，５−ａ］ピリミジン化合物 Expired - Fee Related JP4846665B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2007175769A JP4846665B2 (ja) 2006-07-05 2007-07-04 ピラゾロ［１，５−ａ］ピリミジン化合物

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP2006185036 2006-07-05
JP2006185036 2006-07-05
JP2007009706 2007-01-19
JP2007009706 2007-01-19
JP2007059332 2007-03-09
JP2007059332 2007-03-09
JP2007111340 2007-04-20
JP2007111340 2007-04-20
JP2007175769A JP4846665B2 (ja) 2006-07-05 2007-07-04 ピラゾロ［１，５−ａ］ピリミジン化合物

Publications (3)

Publication Number Publication Date
JP2008285464A JP2008285464A (ja) 2008-11-27
JP2008285464A5 true JP2008285464A5 (https=) 2009-04-09
JP4846665B2 JP4846665B2 (ja) 2011-12-28

Family

ID=40145540

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007175769A Expired - Fee Related JP4846665B2 (ja) 2006-07-05 2007-07-04 ピラゾロ［１，５−ａ］ピリミジン化合物

Country Status (2)

Country Link
JP (1) JP4846665B2 (https=)
TW (2) TWI419889B (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY30090A1 (es) * 2006-01-16 2007-08-31 Syngenta Participations Ag Insecticidas novedosos
WO2010033941A1 (en) 2008-09-22 2010-03-25 Array Biopharma Inc. Substituted imidazo[1,2b]pyridazine compounds as trk kinase inhibitors
MY169791A (en) 2008-10-22 2019-05-15 Array Biopharma Inc Substituted pyrazolo [1,5-a] pyrimidine compounds as trk kinase inhibitors
EP2348860B1 (en) * 2008-10-31 2015-05-27 Genentech, Inc. Pyrazolopyrimidine jak inhibitor compounds and methods
AR077468A1 (es) 2009-07-09 2011-08-31 Array Biopharma Inc Compuestos de pirazolo (1,5 -a) pirimidina sustituidos como inhibidores de trk- quinasa
ME03376B (me) 2010-05-20 2020-01-20 Array Biopharma Inc Makrociklička jedinjenja kао inhibiтori trk kinaze
WO2012030170A2 (ko) * 2010-08-31 2012-03-08 (주)아모레퍼시픽 카나비노이드 1 수용체 저해제로 작용하는 신규 화합물
US8796305B2 (en) * 2012-11-05 2014-08-05 Bayer Pharma Aktiengesellschaft Carboxy-substituted imidazo[1,2-a]pyridinecarboxamides and their use
CN113354649B (zh) 2014-11-16 2024-12-10 阵列生物制药公司 一种新的晶型
WO2017048702A1 (en) * 2015-09-14 2017-03-23 Infinity Pharmaceuticals, Inc. Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same
EP3156405A1 (en) 2015-10-13 2017-04-19 Boehringer Ingelheim International GmbH Spirocyclic ether derivatives of pyrazolo[1,5-a]pyrimidine-3-carboxamide
EP3368039A1 (en) 2015-10-26 2018-09-05 The Regents of The University of Colorado, A Body Corporate Point mutations in trk inhibitor-resistant cancer and methods relating to the same
US10045991B2 (en) 2016-04-04 2018-08-14 Loxo Oncology, Inc. Methods of treating pediatric cancers
FI3439662T3 (fi) 2016-04-04 2024-09-04 Loxo Oncology Inc (s)-n-(5-((r)-2-(2,5-difluorifenyyli)pyrrolidin-1-yyli)pyratsolo[1,5-a]pyrimidin-3-yyli)-3-hydroksipyrrolidiini-1-karboksamidin nesteformulaatioita
EP3458456B1 (en) 2016-05-18 2020-11-25 Loxo Oncology Inc. Preparation of (s)-n-(5-((r)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
JOP20190092A1 (ar) 2016-10-26 2019-04-25 Array Biopharma Inc عملية لتحضير مركبات بيرازولو[1، 5-a]بيريميدين وأملاح منها
JOP20190213A1 (ar) 2017-03-16 2019-09-16 Array Biopharma Inc مركبات حلقية ضخمة كمثبطات لكيناز ros1

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003240488A1 (en) * 2002-06-04 2003-12-19 Neogenesis Pharmaceuticals, Inc. Pyrazolo` 1,5a! pyrimidine compounds as antiviral agents
US7329658B2 (en) * 2003-02-06 2008-02-12 Pfizer Inc Cannabinoid receptor ligands and uses thereof
US7176210B2 (en) * 2003-02-10 2007-02-13 Pfizer Inc. Cannabinoid receptor ligands and uses thereof
DE102004008807A1 (de) * 2004-02-20 2005-09-08 Bayer Cropscience Ag Pyrazolopyrimidine
WO2005103052A1 (en) * 2004-04-21 2005-11-03 Pfizer Products Inc. Pyrazolo [1,5-a] pyrimidin-7-one compounds and uses thereof
JP4847275B2 (ja) * 2005-10-21 2011-12-28 田辺三菱製薬株式会社 ピラゾロ［１，５−ａ］ピリミジン化合物
AR056876A1 (es) * 2005-10-21 2007-10-31 Tanabe Seiyaku Co Compuestos de pirazolo[1-5-a]pirimidina, antagonistas de receptores canabinoides cb1, composiciones farmaceuticas que los contienen y usos en el tratamiento de enfermedades del sistema nervioso central, tales como trastornos psicoticos, neurologicos y similares

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