JP2021519785A5 - - Google Patents
Info
- Publication number
- JP2021519785A5 JP2021519785A5 JP2020552868A JP2020552868A JP2021519785A5 JP 2021519785 A5 JP2021519785 A5 JP 2021519785A5 JP 2020552868 A JP2020552868 A JP 2020552868A JP 2020552868 A JP2020552868 A JP 2020552868A JP 2021519785 A5 JP2021519785 A5 JP 2021519785A5
- Authority
- JP
- Japan
- Prior art keywords
- item
- compound
- pharmaceutically acceptable
- acceptable salt
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862650777P | 2018-03-30 | 2018-03-30 | |
| US62/650,777 | 2018-03-30 | ||
| US201862740549P | 2018-10-03 | 2018-10-03 | |
| US62/740,549 | 2018-10-03 | ||
| PCT/US2019/024729 WO2019191526A1 (en) | 2018-03-30 | 2019-03-29 | Piperidine compounds as covalent menin inhibitors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021519785A JP2021519785A (ja) | 2021-08-12 |
| JP2021519785A5 true JP2021519785A5 (https=) | 2022-04-06 |
Family
ID=68060814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020552868A Pending JP2021519785A (ja) | 2018-03-30 | 2019-03-29 | 共有結合性メニン阻害剤としてのピペリジン化合物 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US20210115018A1 (https=) |
| EP (1) | EP3774731A4 (https=) |
| JP (1) | JP2021519785A (https=) |
| KR (1) | KR20200136958A (https=) |
| CN (1) | CN111936465A (https=) |
| AU (1) | AU2019243587A1 (https=) |
| BR (1) | BR112020020059A2 (https=) |
| CA (1) | CA3093454A1 (https=) |
| IL (1) | IL277659A (https=) |
| MX (1) | MX2020010181A (https=) |
| PH (1) | PH12020551580A1 (https=) |
| SG (1) | SG11202009543VA (https=) |
| TW (1) | TW202003465A (https=) |
| WO (1) | WO2019191526A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017214367A1 (en) | 2016-06-10 | 2017-12-14 | Vitae Pharmaceuticals, Inc. | Inhibitors of the menin-mll interaction |
| EP3694528A4 (en) * | 2017-10-13 | 2021-07-28 | The Regents of the University of California | MTORC1 MODULATORS |
| CA3112340A1 (en) * | 2018-10-03 | 2020-04-09 | The Regents Of The University Of Michigan | Small molecule menin inhibitors |
| WO2021067215A1 (en) | 2019-09-30 | 2021-04-08 | Agios Pharmaceuticals, Inc. | Piperidine compounds as menin inhibitors |
| EP4132932A4 (en) | 2020-04-07 | 2024-04-17 | Syndax Pharmaceuticals, Inc. | COMBINATIONS OF MENIN INHIBITORS AND CYP3A4 INHIBITORS AND METHODS OF USE THEREOF |
| WO2021207310A1 (en) | 2020-04-08 | 2021-10-14 | Agios Pharmaceuticals, Inc. | Menin inhibitors and methods of use for treating cancer |
| TW202204333A (zh) | 2020-04-08 | 2022-02-01 | 美商阿吉歐斯製藥公司 | Menin抑制劑及治療癌症之使用方法 |
| IL308476A (en) | 2021-05-14 | 2024-01-01 | Syndax Pharmaceuticals Inc | Inhibitors of the menin-mil interaction |
| WO2023056589A1 (en) | 2021-10-08 | 2023-04-13 | Servier Pharmaceuticals Llc | Menin inhibitors and methods of use for treating cancer |
| CN120529900A (zh) | 2022-11-24 | 2025-08-22 | 奥莱松基因组股份有限公司 | 用于治疗癌症的LSD1抑制剂和Menin抑制剂的组合 |
| WO2025106862A1 (en) * | 2023-11-17 | 2025-05-22 | Kura Oncology, Inc. | Methods of treating kit positive cancers with a menin inhibitor |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4767842B2 (ja) * | 2003-04-01 | 2011-09-07 | セラヴァンス， インコーポレーテッド | β２アドレナリン作用性レセプターアゴニスト活性およびムスカリン性レセプターアンタゴニスト活性を有するジアリールメチル化合物および関連化合物 |
| US9212180B2 (en) * | 2013-06-12 | 2015-12-15 | The Regents Of The University Of Michigan | Menin-MLL inhibitors and methods of use thereof |
| JP6991585B2 (ja) * | 2016-05-02 | 2022-01-12 | ザ リージェンツ オブ ザ ユニヴァシティ オブ ミシガン | メニン阻害剤としてのピペリジン |
| WO2018106818A1 (en) * | 2016-12-07 | 2018-06-14 | Kura Oncology, Inc. | Methods of promoting beta cell proliferation |
| MX2019011412A (es) * | 2017-03-31 | 2020-02-07 | Univ Michigan Regents | Piperidinas como inhibidores de menina covalentes. |
-
2019
- 2019-03-29 EP EP19777864.0A patent/EP3774731A4/en not_active Withdrawn
- 2019-03-29 TW TW108111416A patent/TW202003465A/zh unknown
- 2019-03-29 CN CN201980023575.6A patent/CN111936465A/zh active Pending
- 2019-03-29 BR BR112020020059-0A patent/BR112020020059A2/pt not_active Application Discontinuation
- 2019-03-29 US US17/040,159 patent/US20210115018A1/en not_active Abandoned
- 2019-03-29 CA CA3093454A patent/CA3093454A1/en active Pending
- 2019-03-29 SG SG11202009543VA patent/SG11202009543VA/en unknown
- 2019-03-29 JP JP2020552868A patent/JP2021519785A/ja active Pending
- 2019-03-29 KR KR1020207030633A patent/KR20200136958A/ko not_active Ceased
- 2019-03-29 MX MX2020010181A patent/MX2020010181A/es unknown
- 2019-03-29 WO PCT/US2019/024729 patent/WO2019191526A1/en not_active Ceased
- 2019-03-29 AU AU2019243587A patent/AU2019243587A1/en not_active Abandoned
-
2020
- 2020-09-28 PH PH12020551580A patent/PH12020551580A1/en unknown
- 2020-09-29 IL IL277659A patent/IL277659A/en unknown