JP2021513986A5 - - Google Patents

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Publication number
JP2021513986A5
JP2021513986A5 JP2020543634A JP2020543634A JP2021513986A5 JP 2021513986 A5 JP2021513986 A5 JP 2021513986A5 JP 2020543634 A JP2020543634 A JP 2020543634A JP 2020543634 A JP2020543634 A JP 2020543634A JP 2021513986 A5 JP2021513986 A5 JP 2021513986A5
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JP
Japan
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pharmaceutical composition
item
composition according
cancer
compound
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JP2020543634A
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English (en)
Japanese (ja)
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JP2021513986A (ja
JP7445597B2 (ja
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Priority claimed from PCT/US2019/018225 external-priority patent/WO2019168688A2/en
Publication of JP2021513986A publication Critical patent/JP2021513986A/ja
Publication of JP2021513986A5 publication Critical patent/JP2021513986A5/ja
Application granted granted Critical
Publication of JP7445597B2 publication Critical patent/JP7445597B2/ja
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JP2020543634A 2018-02-15 2019-02-15 キノロン類似体及びそれらの塩、組成物、ならびにそれらの使用方法 Active JP7445597B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201862631171P 2018-02-15 2018-02-15
US201862631174P 2018-02-15 2018-02-15
US62/631,171 2018-02-15
US62/631,174 2018-02-15
PCT/US2019/018225 WO2019168688A2 (en) 2018-02-15 2019-02-15 Quinolone analogs and their salts, compositions, and method for their use

Publications (3)

Publication Number Publication Date
JP2021513986A JP2021513986A (ja) 2021-06-03
JP2021513986A5 true JP2021513986A5 (enExample) 2023-06-19
JP7445597B2 JP7445597B2 (ja) 2024-03-07

Family

ID=67805108

Family Applications (1)

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JP2020543634A Active JP7445597B2 (ja) 2018-02-15 2019-02-15 キノロン類似体及びそれらの塩、組成物、ならびにそれらの使用方法

Country Status (11)

Country Link
US (2) US20190374550A1 (enExample)
EP (1) EP3752149A4 (enExample)
JP (1) JP7445597B2 (enExample)
KR (1) KR102914215B1 (enExample)
CN (1) CN112334133A (enExample)
AU (1) AU2019227294B2 (enExample)
CA (1) CA3088998A1 (enExample)
IL (1) IL276513A (enExample)
RU (1) RU2020130050A (enExample)
TW (1) TWI884912B (enExample)
WO (1) WO2019168688A2 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119185322A (zh) 2015-11-20 2024-12-27 生华生物科技股份有限公司 用于治疗癌症的四环喹诺酮类似物组合疗法
EP3752149A4 (en) 2018-02-15 2022-03-02 Senhwa Biosciences, Inc. QUINOLONE ANALOGUES AND THEIR SALTS, COMPOSITIONS AND METHODS OF USE
US20210046071A1 (en) * 2019-08-14 2021-02-18 Senhwa Biosciences, Inc. Tetracyclic compounds and their salts, compositions, and methods for their use
WO2021030686A1 (en) * 2019-08-14 2021-02-18 Senhwa Biosciences, Inc. Crystalline forms of quinoline analogs and salts thereof, compositions, and their methods for use
WO2022051491A1 (en) * 2020-09-02 2022-03-10 Senhwa Biosciences, Inc. Pharmaceutical compositions of tetracyclic quinolone analogs and their salts
WO2023059148A1 (ko) * 2021-10-08 2023-04-13 기초과학연구원 항암 치료 개선을 위한 2-클로로-n,n-디에틸에틸아민 염산염의 용도
CN118005653B (zh) * 2023-04-23 2024-12-10 信义核新(北京)生物科技有限公司 喹诺酮类似物及其用途

Family Cites Families (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4559157A (en) 1983-04-21 1985-12-17 Creative Products Resource Associates, Ltd. Cosmetic applicator useful for skin moisturizing
LU84979A1 (fr) 1983-08-30 1985-04-24 Oreal Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux
US4820508A (en) 1987-06-23 1989-04-11 Neutrogena Corporation Skin protective composition
US4992478A (en) 1988-04-04 1991-02-12 Warner-Lambert Company Antiinflammatory skin moisturizing composition and method of preparing same
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
US5703055A (en) 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
ATE269848T1 (de) 1999-04-07 2004-07-15 Univ Virginia Calciumkanalblocker als antikrebsmittel
AU2002361493A1 (en) 2001-12-13 2003-06-23 Wockhardt Limited New generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
US6900224B2 (en) 2002-07-31 2005-05-31 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
PL1633724T3 (pl) 2003-03-12 2011-10-31 Kudos Pharm Ltd Pochodne ftalazynonu
MXPA06000993A (es) 2003-07-25 2006-08-31 Cancer Rec Tech Ltd Inhbidores triciclicos de parp.
US20050118291A1 (en) 2003-09-10 2005-06-02 Mian-Ying Wang Formulations and methods for treating breast cancer with Morinda citrifolia and methylsulfonymethane
WO2005033108A1 (en) 2003-09-22 2005-04-14 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
SG150548A1 (en) 2003-12-01 2009-03-30 Kudos Pharm Ltd Dna damage repair inhibitors for treatment of cancer
LT2612862T (lt) 2004-05-13 2017-01-25 Icos Corporation Chinazolinonai kaip žmogaus fosfatidilinozitol-3-kinazės delta inhibitoriai
NZ553746A (en) 2004-09-17 2010-06-25 Cylene Pharmaceuticals Inc Quinolone analogs as cell proliferation inhibitors
EP1928887B1 (en) 2005-08-05 2014-12-17 Senhwa Biosciences, Inc. Methods of preparing quinolone analogs
EP1926372A2 (en) 2005-08-19 2008-06-04 Cylene Pharmaceuticals, Inc. HUMAN RIBOSOMAL DNA(rDNA) AND RIBOSOMAL RNA (rRNA) NUCLEIC ACIDS AND USES THEREOF
AR057555A1 (es) 2005-10-27 2007-12-05 Merck Frosst Canada Ltd Un inhibidor de fosfodiesterasa-4 4-oxo-1-(3-sustituido fenil-1,4-dihidro-1,8-naftiridin-3-carboxamida y un procedimiento de preparacion del mismo
WO2007056113A2 (en) 2005-11-02 2007-05-18 Cylene Pharmaceuticals, Inc. Methods for targeting quadruplex sequences
US20100063046A1 (en) 2006-05-17 2010-03-11 Whitten Jeffrey P Tetracyclic imidazole analogs
WO2007146831A2 (en) 2006-06-08 2007-12-21 Cylene Pharmaceuticals, Inc. Quinolone analogs derivatized with sulfonic acid, sulfonate or sulfonamide
US20110112086A1 (en) 2006-06-08 2011-05-12 Cylene Pharmaceuticals, Inc. Pyridinone analogs
GB0701992D0 (en) 2007-02-02 2007-03-14 7Tm Pharma As Grehlin Receptor Modulators
WO2008131134A1 (en) 2007-04-17 2008-10-30 Cylene Pharmaceuticals, Inc. Hydrazide compounds and uses thereof
KR101601332B1 (ko) 2007-10-05 2016-03-08 센화 바이오사이언시즈 인코포레이티드 퀴놀론 유사체 및 이와 관련된 방법
AU2008201871A1 (en) 2008-04-16 2009-11-26 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts Inhibition of angiogenesis and tumor metastasis
WO2012122645A1 (en) 2011-03-11 2012-09-20 Sarissa Inc. Methods of treating cancer by inhibition of dna repair proteins
WO2012123938A1 (en) 2011-03-17 2012-09-20 Tel Hashomer Medical Research Infrastructure And Services Ltd. Quinolone analogs for treating autoimmune diseases
WO2013133876A1 (en) 2011-12-07 2013-09-12 The Regents Of The University Of California Biomarkers for prediction of response to parp inhibition in breast cancer
US9044421B2 (en) 2012-03-28 2015-06-02 Genus Oncology, Llc Treating MUC1-expressing cancers with combination therapies
US9856320B2 (en) 2012-05-15 2018-01-02 Bristol-Myers Squibb Company Cancer immunotherapy by disrupting PD-1/PD-L1 signaling
WO2014209804A1 (en) 2013-06-24 2014-12-31 Biomed Valley Discoveries, Inc. Bispecific antibodies
EP3074391B1 (en) * 2013-11-28 2019-07-31 Tel Hashomer Medical Research Infrastructure And Services Ltd. Rna polymerase i inhibitors and uses thereof
PT3134123T (pt) 2014-02-21 2021-03-22 Nektar Therapeutics India Pvt Ltd Agonistas seletivos de il-2rbeta em combinação com um anticorpo anti-ctla-4 ou um anticorpo anti-pd-1
CN119185322A (zh) 2015-11-20 2024-12-27 生华生物科技股份有限公司 用于治疗癌症的四环喹诺酮类似物组合疗法
ES2959536T3 (es) * 2015-12-14 2024-02-26 Senhwa Biosciences Inc Formas cristalinas de análogos de quinolona y sus sales
US9957282B2 (en) * 2015-12-14 2018-05-01 Senhwa Biosciences, Inc. Crystalline forms of quinolone analogs and their salts
WO2017100925A1 (en) 2015-12-15 2017-06-22 British Columbia Cancer Agency Branch Metal complexed therapeutic agents and lipid-based nanoparticulate formulations thereof
WO2017205832A1 (en) * 2016-05-26 2017-11-30 Fred Hutchinson Cancer Research Center L-myc pathway targeting as a treatment for small cell lung cancer
EP3752149A4 (en) 2018-02-15 2022-03-02 Senhwa Biosciences, Inc. QUINOLONE ANALOGUES AND THEIR SALTS, COMPOSITIONS AND METHODS OF USE
WO2021030686A1 (en) 2019-08-14 2021-02-18 Senhwa Biosciences, Inc. Crystalline forms of quinoline analogs and salts thereof, compositions, and their methods for use
US20210046071A1 (en) 2019-08-14 2021-02-18 Senhwa Biosciences, Inc. Tetracyclic compounds and their salts, compositions, and methods for their use
WO2022051491A1 (en) 2020-09-02 2022-03-10 Senhwa Biosciences, Inc. Pharmaceutical compositions of tetracyclic quinolone analogs and their salts

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