JP2021510818A5 - - Google Patents
Info
- Publication number
- JP2021510818A5 JP2021510818A5 JP2020538841A JP2020538841A JP2021510818A5 JP 2021510818 A5 JP2021510818 A5 JP 2021510818A5 JP 2020538841 A JP2020538841 A JP 2020538841A JP 2020538841 A JP2020538841 A JP 2020538841A JP 2021510818 A5 JP2021510818 A5 JP 2021510818A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- mmol
- compound according
- disease
- compound
- Prior art date
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2023143506A JP7692963B2 (ja) | 2018-01-11 | 2023-09-05 | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862616253P | 2018-01-11 | 2018-01-11 | |
| US62/616,253 | 2018-01-11 | ||
| PCT/US2019/013193 WO2019140188A1 (en) | 2018-01-11 | 2019-01-11 | Inhibitors of dihydroceramide desaturase for treating disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023143506A Division JP7692963B2 (ja) | 2018-01-11 | 2023-09-05 | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021510818A JP2021510818A (ja) | 2021-04-30 |
| JP2021510818A5 true JP2021510818A5 (https=) | 2022-01-19 |
| JPWO2019140188A5 JPWO2019140188A5 (https=) | 2022-01-19 |
| JP7346425B2 JP7346425B2 (ja) | 2023-09-19 |
Family
ID=67219929
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020538841A Active JP7346425B2 (ja) | 2018-01-11 | 2019-01-11 | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
| JP2023143506A Active JP7692963B2 (ja) | 2018-01-11 | 2023-09-05 | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023143506A Active JP7692963B2 (ja) | 2018-01-11 | 2023-09-05 | 疾患を治療するためのジヒドロセラミドデサチュラーゼ阻害剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (3) | US11597715B2 (https=) |
| EP (1) | EP3737361A4 (https=) |
| JP (2) | JP7346425B2 (https=) |
| KR (1) | KR20250057925A (https=) |
| CN (1) | CN111787916B (https=) |
| AU (1) | AU2019207887B2 (https=) |
| CA (1) | CA3087729A1 (https=) |
| WO (1) | WO2019140188A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11970486B2 (en) | 2016-10-24 | 2024-04-30 | Janssen Pharmaceutica Nv | Compounds and uses thereof |
| US11135207B2 (en) | 2016-12-13 | 2021-10-05 | Centaurus Therapeutics | Inhibitors of dihydroceramide desaturase for treating disease |
| EA201991650A1 (ru) | 2017-01-06 | 2020-01-20 | Юманити Терапьютикс, Инк. | Способы лечения неврологических расстройств |
| CA3083000A1 (en) | 2017-10-24 | 2019-05-02 | Yumanity Therapeutics, Inc. | Compounds and uses thereof |
| CN111787916B (zh) * | 2018-01-11 | 2023-09-05 | 森陶鲁斯治疗公司 | 用于治疗疾病的二氢神经酰胺去饱和酶抑制剂 |
| BR112020019191A2 (pt) | 2018-03-23 | 2021-01-05 | Yumanity Therapeutics, Inc. | Compostos e seus usos |
| MX2021008903A (es) * | 2019-01-24 | 2021-11-04 | Yumanity Therapeutics Inc | Compuestos y usos de los mismos. |
| WO2020168294A1 (en) | 2019-02-15 | 2020-08-20 | Lysosomal And Rare Disorders Research And Treatment Center, Llc | Methods and compositions for treating lysosomal storage disorders: ambroxol as treatment agent for mucopolysaccharidoses iii (sanfilippo syndrome) |
| EA202192047A1 (ru) | 2019-11-13 | 2021-12-08 | Юманити Терапьютикс, Инк. | Соединения и их применение |
| WO2022115612A1 (en) * | 2020-11-25 | 2022-06-02 | Lysosomal and Rare Disorders Research and Treatment Center, Inc. | Inhibition of caspase pathway as a treatment for lysosomal storage disorders |
| EP4378938A4 (en) * | 2021-07-29 | 2025-04-02 | Shanghai Qilu Pharmaceutical Research and Development Centre Ltd. | NEW PARP7 INHIBITOR AND USE THEREOF |
| US20240343727A1 (en) * | 2021-08-17 | 2024-10-17 | InventisBio Co., Ltd. | Pyridazinone or pyridinone compounds, preparation methods and uses thereof |
| CN120136787A (zh) * | 2023-12-13 | 2025-06-13 | 青岛清原化合物有限公司 | 一种吡唑取代的芳基硫化物类化合物及其应用 |
Family Cites Families (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS62249945A (ja) | 1986-04-23 | 1987-10-30 | Fuji Photo Film Co Ltd | ハイドロキノン・モノエステル類の合成方法 |
| US6124299A (en) | 1997-02-24 | 2000-09-26 | Zymogenetics, Inc. | Calcitonin mimetics |
| FR2770131A1 (fr) | 1997-10-27 | 1999-04-30 | Union Pharma Scient Appl | Nouvelle association pharmaceutique a activite analgesique |
| US6375957B1 (en) | 1997-12-22 | 2002-04-23 | Euro-Celtique, S.A. | Opioid agonist/opioid antagonist/acetaminophen combinations |
| CO5150173A1 (es) | 1998-12-10 | 2002-04-29 | Novartis Ag | Compuestos n-(glicilo sustituido)-2-cianopirrolidinas inhibidores de peptidasa de dipeptidilo-iv (dpp-iv) los cuales son efectivos en el tratamiento de condiciones mediadas por la inhibicion de dpp-iv |
| US6894063B2 (en) | 2000-09-14 | 2005-05-17 | Schering Corporation | Substituted urea neuropeptide Y Y5 Receptor antagonists |
| ES2170030B1 (es) | 2000-12-19 | 2003-11-16 | Consejo Superior Investigacion | Inhibidores de la dihidroceramida desaturasa. |
| US6667319B2 (en) | 2001-07-26 | 2003-12-23 | Schering-Plough Corporation | Neuropeptide Y Y5 receptor antagonists |
| EP1636187A1 (en) | 2003-06-12 | 2006-03-22 | Novo Nordisk A/S | Substituted piperazine carbamates for use as inhibitors of hormone sensitive lipase |
| AU2004247320A1 (en) | 2003-06-12 | 2004-12-23 | Novo Nordisk A/S | 1-aryl-4-(aryloxycarbonyl)-piperazine derivatives for use as inhibitors of hormone sensitive lipase |
| US7129235B2 (en) | 2003-07-11 | 2006-10-31 | Abbott Laboratories | Amides useful for treating pain |
| JP2007501805A (ja) | 2003-08-08 | 2007-02-01 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ピリジルピペラジニルウレア |
| US7491720B2 (en) | 2004-10-29 | 2009-02-17 | Banyu Pharmaceutical Co., Ltd. | Aminopyridine derivatives having Aurora A selective inhibitory action |
| TW200633990A (en) | 2004-11-18 | 2006-10-01 | Takeda Pharmaceuticals Co | Amide compound |
| US8143257B2 (en) | 2004-11-23 | 2012-03-27 | Ptc Therapeutics, Inc. | Substituted phenols as active agents inhibiting VEGF production |
| AR055831A1 (es) | 2004-12-30 | 2007-09-12 | Janssen Pharmaceutica Nv | Pepirazinilureas y piperidinilureas como moduladores de hidrolasa de amida de acidos grasos |
| ES2528674T3 (es) * | 2005-02-17 | 2015-02-11 | Astellas Pharma Inc. | Piperidina y carboxilatos de piperacina como inhibidores de FAAH |
| US7790726B2 (en) | 2005-08-16 | 2010-09-07 | Chemocentryx, Inc. | Monocyclic and bicyclic compounds and methods of use |
| US20100048714A1 (en) | 2006-06-19 | 2010-02-25 | University Of Utah Research Foundation | Methods and Compositions Related to Inhibition of Ceramide Synthesis |
| US20110172230A1 (en) | 2006-08-23 | 2011-07-14 | Takahiro Ishii | Urea compound or salt thereof |
| KR20110065417A (ko) | 2008-01-03 | 2011-06-15 | 욱크하르트 리미티드 | 파라세타몰 및 이부프로펜을 포함하는 경구 약제학적 현탁액 |
| WO2010023512A1 (en) | 2008-08-28 | 2010-03-04 | Matrix Laboratories Ltd. | Novel vanilloid receptor modulators, process for their preparation and pharmaceutical compositions containing them |
| FR2939135B1 (fr) | 2008-12-02 | 2010-12-03 | Galderma Res & Dev | Nouveaux composes 4-(azacycloalkyl)-benzene-1,3-diol comme inhibiteurs de la tyrosinase, leur procede de preparation et leur utilisation en medecine humaine ainsi qu'en cosmetique |
| CN102365275B (zh) | 2009-01-28 | 2014-09-24 | 里格尔药品股份有限公司 | 羧酰胺化合物及其使用方法 |
| JP2010195688A (ja) | 2009-02-23 | 2010-09-09 | Shionogi & Co Ltd | Ｎｐｙｙ５受容体拮抗作用を有するアミド及びウレア誘導体 |
| EP2518064A1 (en) | 2009-12-25 | 2012-10-31 | Mochida Pharmaceutical Co., Ltd. | Novel aryl urea derivative |
| CN103172635B (zh) * | 2011-12-21 | 2016-04-27 | 上海医药工业研究院 | 哌嗪或哌啶类化合物、其盐、中间体、制备方法及应用 |
| EP3043822A1 (en) * | 2013-09-11 | 2016-07-20 | The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone | Compositions for preparing cardiomyocytes |
| BR112018076258A2 (pt) | 2016-06-30 | 2019-03-26 | Basilea Pharm Int Ag | inibidores mitocondriais para o tratamento de distúrbios de proliferação |
| US11135207B2 (en) * | 2016-12-13 | 2021-10-05 | Centaurus Therapeutics | Inhibitors of dihydroceramide desaturase for treating disease |
| CN111787916B (zh) * | 2018-01-11 | 2023-09-05 | 森陶鲁斯治疗公司 | 用于治疗疾病的二氢神经酰胺去饱和酶抑制剂 |
-
2019
- 2019-01-11 CN CN201980015846.3A patent/CN111787916B/zh active Active
- 2019-01-11 CA CA3087729A patent/CA3087729A1/en active Pending
- 2019-01-11 JP JP2020538841A patent/JP7346425B2/ja active Active
- 2019-01-11 KR KR1020257012348A patent/KR20250057925A/ko active Pending
- 2019-01-11 WO PCT/US2019/013193 patent/WO2019140188A1/en not_active Ceased
- 2019-01-11 AU AU2019207887A patent/AU2019207887B2/en active Active
- 2019-01-11 EP EP19738156.9A patent/EP3737361A4/en active Pending
- 2019-01-11 US US16/959,807 patent/US11597715B2/en active Active
-
2023
- 2023-02-06 US US18/106,305 patent/US12247019B2/en active Active
- 2023-09-05 JP JP2023143506A patent/JP7692963B2/ja active Active
-
2025
- 2025-01-24 US US19/036,846 patent/US20260070884A1/en active Pending
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