JP2021506253A5 - - Google Patents
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- Publication number
- JP2021506253A5 JP2021506253A5 JP2020532561A JP2020532561A JP2021506253A5 JP 2021506253 A5 JP2021506253 A5 JP 2021506253A5 JP 2020532561 A JP2020532561 A JP 2020532561A JP 2020532561 A JP2020532561 A JP 2020532561A JP 2021506253 A5 JP2021506253 A5 JP 2021506253A5
- Authority
- JP
- Japan
- Prior art keywords
- analyte
- phase
- mixture
- atps
- substrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 20
- 239000012491 analyte Substances 0.000 claims 14
- 239000000203 mixture Substances 0.000 claims 11
- 101100202428 Neopyropia yezoensis atps gene Proteins 0.000 claims 6
- 239000000523 sample Substances 0.000 claims 6
- 239000000758 substrate Substances 0.000 claims 6
- 239000002202 Polyethylene glycol Substances 0.000 claims 5
- 229920001223 polyethylene glycol Polymers 0.000 claims 5
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 claims 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 3
- 238000010438 heat treatment Methods 0.000 claims 2
- 150000003839 salts Chemical class 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 239000012472 biological sample Substances 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 238000010494 dissociation reaction Methods 0.000 claims 1
- 230000005593 dissociations Effects 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 239000002207 metabolite Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 239000001509 sodium citrate Substances 0.000 claims 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762598802P | 2017-12-14 | 2017-12-14 | |
| US62/598,802 | 2017-12-14 | ||
| US201862692001P | 2018-06-29 | 2018-06-29 | |
| US62/692,001 | 2018-06-29 | ||
| PCT/US2018/065421 WO2019118705A1 (en) | 2017-12-14 | 2018-12-13 | Concentration of analytes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021506253A JP2021506253A (ja) | 2021-02-22 |
| JP2021506253A5 true JP2021506253A5 (https=) | 2021-12-23 |
| JP7270992B2 JP7270992B2 (ja) | 2023-05-11 |
Family
ID=66815084
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020532561A Active JP7270992B2 (ja) | 2017-12-14 | 2018-12-13 | 分析物の濃縮 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20190187031A1 (https=) |
| EP (1) | EP3724317A4 (https=) |
| JP (1) | JP7270992B2 (https=) |
| CN (1) | CN111971380A (https=) |
| WO (1) | WO2019118705A1 (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12065698B2 (en) * | 2009-10-02 | 2024-08-20 | Thermo Fisher Scientific Baltics Uab | Sample processing apparatus and method |
| JP2019505884A (ja) * | 2015-12-10 | 2019-02-28 | キアゲン ゲーエムベーハー | デジタル画像内の少なくとも１つのオブジェクトの全体的明るさを判定するための方法 |
| AU2018231211A1 (en) | 2017-03-08 | 2019-10-03 | The Regents Of The University Of Michigan | Analyte detection |
| WO2018183465A1 (en) | 2017-03-28 | 2018-10-04 | Chiu Yin To | Method for accurate diagnosis of a disease targeting biomarkers in liquid biopsy |
| EP4303311A3 (en) | 2017-09-18 | 2024-04-03 | Phase Scientific International, Ltd. | Method for using aqueous two-phase system for the isolation, purification and/or concentration of short nucleic acid fragments |
| US12043826B2 (en) | 2018-01-19 | 2024-07-23 | Phase Scientific International, Ltd. | Spontaneous nucleic acid purification and concentration in a single step |
| WO2020023503A1 (en) * | 2018-07-24 | 2020-01-30 | The Regents Of The University Of Michigan | Intramolecular kinetic probes |
| KR20250047414A (ko) * | 2019-07-16 | 2025-04-03 | 멜리오랩스 인코포레이티드 | 단일-세포 기반 디지털 고해상도 용융을 위한 방법 및 장치 |
| WO2021154935A1 (en) | 2020-01-29 | 2021-08-05 | The Regents Of The University Of Michigan | Analyte detection |
| WO2021188308A1 (en) * | 2020-03-19 | 2021-09-23 | The Regents Of The University Of Michigan | Analyte detection |
| EP4121530A1 (en) | 2020-03-20 | 2023-01-25 | Phase Scientific International, Ltd. | Compositions and methods for ribonucleic acid extraction |
| US20240140981A1 (en) * | 2020-12-29 | 2024-05-02 | Curative Inc. | Nucleic acid purification methods using a water-immiscible solvent wash |
| JP2024513919A (ja) * | 2021-04-06 | 2024-03-27 | エックスゲノムズ コーポレーション | 核酸のエピジェネティックな修飾を検出するためのシステム、方法、及び組成物 |
| CN113324619B (zh) * | 2021-06-02 | 2023-06-06 | 成都瀚辰光翼科技有限责任公司 | 一种基于电容检测的液面探测方法及装置 |
| CN118414544A (zh) | 2021-12-21 | 2024-07-30 | 生物辐射实验室股份有限公司 | 通过测量局部荧光比率在高分辨率装置中进行多重检测 |
| WO2024064787A2 (en) * | 2022-09-21 | 2024-03-28 | Ultragenyx Pharmaceutical Inc. | Method for determination of double-stranded rna impurity |
| CN119137270A (zh) | 2022-11-02 | 2024-12-13 | 相达生物科技国际有限公司 | 使用atps和固相介质从生物样品分离目标分析物的方法 |
| WO2024093522A1 (en) * | 2022-11-02 | 2024-05-10 | Phase Scientific International, Ltd. | Methods, compositions and kits for concentrating target analytes from a bulk fluid sample |
| AU2023374887A1 (en) * | 2022-11-02 | 2025-05-22 | Phase Scientific International, Ltd. | Methods and kits for isolating target nucleic acids below a target size from a sample |
| CN116103375B (zh) * | 2022-11-11 | 2025-11-14 | 北京理工大学 | 基于dna折纸的纳米标尺及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020081629A1 (en) * | 2000-06-30 | 2002-06-27 | Tibotec N.V. | Apparatus for the simultaneous transfer of liquid analytes |
| US20060094033A1 (en) * | 2004-05-21 | 2006-05-04 | Carl Abulencia | Screening methods and libraries of trace amounts of DNA from uncultivated microorganisms |
| EP2350113A4 (en) * | 2008-11-25 | 2013-01-02 | Ge Healthcare Bio Sciences Ab | FOR AN AQUEOUS TWO-PHASE EXTRACTION REINFORCED DEPOSITION PROCESS FOR CLEANING THERAPEUTIC PROTEINS |
| EP2548022B1 (en) * | 2010-03-18 | 2016-03-16 | The Regents Of The University Of Michigan | Multiphase microarrays and uses thereof |
| WO2013039449A1 (en) * | 2011-09-16 | 2013-03-21 | Ge Healthcare Bio-Sciences Ab | Plasma protein fractionation by sequential polyacid precipitation |
| EP3114482B1 (en) * | 2014-03-07 | 2020-10-07 | The Regents of the University of California | Devices for integrating analyte extraction, concentration and detection |
| WO2017041030A1 (en) * | 2015-09-04 | 2017-03-09 | The Regents Of The University Of California | Methods and devices for analyte collection, extraction, concentration, and detection for clinical applications |
| CN114196746A (zh) * | 2016-02-10 | 2022-03-18 | 密歇根大学董事会 | 核酸的检测 |
-
2018
- 2018-12-13 CN CN201880089480.XA patent/CN111971380A/zh active Pending
- 2018-12-13 JP JP2020532561A patent/JP7270992B2/ja active Active
- 2018-12-13 US US16/219,070 patent/US20190187031A1/en not_active Abandoned
- 2018-12-13 WO PCT/US2018/065421 patent/WO2019118705A1/en not_active Ceased
- 2018-12-13 EP EP18888885.3A patent/EP3724317A4/en not_active Withdrawn
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