JP2021504348A5 - - Google Patents

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Publication number
JP2021504348A5
JP2021504348A5 JP2020528244A JP2020528244A JP2021504348A5 JP 2021504348 A5 JP2021504348 A5 JP 2021504348A5 JP 2020528244 A JP2020528244 A JP 2020528244A JP 2020528244 A JP2020528244 A JP 2020528244A JP 2021504348 A5 JP2021504348 A5 JP 2021504348A5
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JP
Japan
Prior art keywords
defensin
human
pharmaceutical composition
defensins
seq
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Application number
JP2020528244A
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English (en)
Japanese (ja)
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JP2021504348A (ja
JP7423523B2 (ja
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Priority claimed from PCT/EP2018/082022 external-priority patent/WO2019101773A2/en
Publication of JP2021504348A publication Critical patent/JP2021504348A/ja
Publication of JP2021504348A5 publication Critical patent/JP2021504348A5/ja
Application granted granted Critical
Publication of JP7423523B2 publication Critical patent/JP7423523B2/ja
Active legal-status Critical Current
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JP2020528244A 2017-11-24 2018-11-21 ディフェンシンによる移植片対宿主病の予防と治療 Active JP7423523B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP17203527 2017-11-24
EP17203527.1 2017-11-24
EP18191954.9 2018-08-31
EP18191954 2018-08-31
PCT/EP2018/082022 WO2019101773A2 (en) 2017-11-24 2018-11-21 Prevention and treatment of graft-versus-host-disease with defensins

Publications (3)

Publication Number Publication Date
JP2021504348A JP2021504348A (ja) 2021-02-15
JP2021504348A5 true JP2021504348A5 (https=) 2022-01-04
JP7423523B2 JP7423523B2 (ja) 2024-01-29

Family

ID=64308771

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020528244A Active JP7423523B2 (ja) 2017-11-24 2018-11-21 ディフェンシンによる移植片対宿主病の予防と治療

Country Status (15)

Country Link
US (1) US20200291082A1 (https=)
EP (1) EP3713590B1 (https=)
JP (1) JP7423523B2 (https=)
KR (1) KR20200097251A (https=)
CN (1) CN111741762A (https=)
AU (1) AU2018371948A1 (https=)
BR (1) BR112020010180A2 (https=)
CA (1) CA3083315A1 (https=)
ES (1) ES3038390T3 (https=)
MX (1) MX2020005370A (https=)
PL (1) PL3713590T3 (https=)
RU (1) RU2020116903A (https=)
SG (1) SG11202004207VA (https=)
WO (1) WO2019101773A2 (https=)
ZA (1) ZA202002669B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102244161B1 (ko) * 2018-08-31 2021-04-26 주식회사 나이벡 다중의 질환 바이오마커의 기능 및 발현을 억제하는 펩타이드의 신규한 용도
KR20230112561A (ko) * 2022-01-20 2023-07-27 가톨릭대학교 산학협력단 간이식환자 장내균총 분석과 이를 통한 이식상태 모니터링과 면역조절 테라그노시스 조성물

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235871A (en) 1978-02-24 1980-11-25 Papahadjopoulos Demetrios P Method of encapsulating biologically active materials in lipid vesicles
US4501728A (en) 1983-01-06 1985-02-26 Technology Unlimited, Inc. Masking of liposomes from RES recognition
US4837028A (en) 1986-12-24 1989-06-06 Liposome Technology, Inc. Liposomes with enhanced circulation time
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
NZ540506A (en) * 2002-12-19 2008-09-26 Yitzchak Hillman Disease treatment via antimicrobial peptide inhibitors
AU2009209565B2 (en) 2008-02-01 2013-09-19 Ascendis Pharma As Prodrug comprising a self-cleavable linker
WO2009113065A1 (en) * 2008-03-13 2009-09-17 Hadasit Medical Research Services & Development Ltd. Immuno-modulating compositions for the treatment of immune-mediated disorders
SG172709A1 (en) 2008-07-18 2011-07-28 Novozymes Adenium Biotech As Treatment of inflammatory bowel diseases with mammal beta defensins
KR101722961B1 (ko) 2009-02-11 2017-04-04 알부메딕스 에이/에스 알부민 변이체 및 접합체
JP6219277B2 (ja) * 2011-07-08 2017-10-25 ディフェンシン セラピューティクス アンパルトセルスカブDefensin Therapeutics Aps 炎症性腸疾患の経口治療
WO2016086161A1 (en) * 2014-11-25 2016-06-02 Memorial Sloan-Kettering Cancer Center Intestinal microbiota and gvhd
CN104971343B (zh) * 2015-07-13 2018-02-02 韩源平 防御素在制备治疗代谢综合征药物方面的应用
BR112018015170A2 (pt) * 2016-01-26 2018-12-18 Defensin Therapeutics Aps métodos para tratamento de doenças, para promoção de crescimento magro, para tratamento ou normalização de uma microbiota disbiótica no intestino, para aumentar riqueza gênica da microbiota intestinal, para aumentar número de filos da microbiota intestinal, para aumentar produção de ácidos graxos de cadeia curta da microbiota intestinal/metaboloma, para aumentar número de bactérias, para diminuir número de bactérias, defensina a, defensina ss, ou um fragmento bioativo das mesmas, e, defensina a e/ou defensina ss e/ou um glp-1/análogo de glp-1.
MX2020004863A (es) * 2017-11-10 2020-10-14 Defensin Therapeutics Aps Maduracion de la defensa de la mucosa y/o funcion intestinal/pulmonar en el bebe prematuro.

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