JP2021503960A5 - - Google Patents
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- Publication number
- JP2021503960A5 JP2021503960A5 JP2020546302A JP2020546302A JP2021503960A5 JP 2021503960 A5 JP2021503960 A5 JP 2021503960A5 JP 2020546302 A JP2020546302 A JP 2020546302A JP 2020546302 A JP2020546302 A JP 2020546302A JP 2021503960 A5 JP2021503960 A5 JP 2021503960A5
- Authority
- JP
- Japan
- Prior art keywords
- receptor
- pharmaceutical composition
- vector
- engineered
- engineered receptor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024105712A JP2024160218A (ja) | 2017-11-27 | 2024-06-28 | 神経疾患のための組成物および方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762590911P | 2017-11-27 | 2017-11-27 | |
| US62/590,911 | 2017-11-27 | ||
| US201862659911P | 2018-04-19 | 2018-04-19 | |
| US62/659,911 | 2018-04-19 | ||
| PCT/US2018/062575 WO2019104307A1 (en) | 2017-11-27 | 2018-11-27 | Compositions and methods for neurological diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024105712A Division JP2024160218A (ja) | 2017-11-27 | 2024-06-28 | 神経疾患のための組成物および方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021503960A JP2021503960A (ja) | 2021-02-15 |
| JP2021503960A5 true JP2021503960A5 (https=) | 2022-01-04 |
Family
ID=66632192
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020546302A Pending JP2021503960A (ja) | 2017-11-27 | 2018-11-27 | 神経疾患のための組成物および方法 |
| JP2024105712A Pending JP2024160218A (ja) | 2017-11-27 | 2024-06-28 | 神経疾患のための組成物および方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024105712A Pending JP2024160218A (ja) | 2017-11-27 | 2024-06-28 | 神経疾患のための組成物および方法 |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10538571B2 (https=) |
| EP (1) | EP3716990A4 (https=) |
| JP (2) | JP2021503960A (https=) |
| KR (2) | KR20200112811A (https=) |
| CN (1) | CN111741760A (https=) |
| AU (2) | AU2018373279B2 (https=) |
| CA (1) | CA3082907A1 (https=) |
| IL (2) | IL274702B2 (https=) |
| MX (2) | MX2020005470A (https=) |
| SG (1) | SG11202004488TA (https=) |
| WO (1) | WO2019104307A1 (https=) |
| ZA (1) | ZA202408862B (https=) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020167624A1 (en) | 2019-02-13 | 2020-08-20 | Ptc Therapeutics, Inc. | Pyrrolo[2,3-d]pyrimidine compounds for treating familial dysautonomia |
| SG11202108519TA (en) | 2019-02-13 | 2021-09-29 | Ptc Therapeutics Inc | Thioeno[3,2-b] pyridin-7-amine compounds for treating familial dysautonomia |
| AU2020334147A1 (en) * | 2019-08-21 | 2022-03-31 | Trames Bio, Inc. | Compositions and methods for neurological diseases |
| WO2021168110A1 (en) * | 2020-02-20 | 2021-08-26 | The Regents Of The University Of California | Therapies for the treatment of diseases and disorders associated with abnormal expression of a neural-associated gene |
| IL300816A (en) * | 2020-08-21 | 2023-04-01 | Trames Bio Inc | Preparations and methods for neurological diseases |
| WO2022067044A1 (en) * | 2020-09-25 | 2022-03-31 | The Regents Of The University Of California | Compositions and methods for ameliorating medical conditions |
| MX2023008738A (es) * | 2021-01-25 | 2023-09-12 | Trames Bio Inc | Cápsides de virus adenoasociados y canales iónicos controlados por ligandos diseñados para el tratamiento contra epilepsia focal y dolor neuropático. |
| US11969400B2 (en) * | 2021-03-23 | 2024-04-30 | Kumara V. Nibhanipudi | Ibuprofen for symptomatic treatment of diarrheas in HIV patients |
| WO2023278295A1 (en) | 2021-06-29 | 2023-01-05 | The Broad Institute, Inc. | Compositions and methods for ameliorating anterodorsal thalamus hyperexcitability |
| CN113730809B (zh) * | 2021-10-09 | 2024-08-16 | 科悦医疗(苏州)有限公司 | 一种非侵入式迷走神经联合骶神经刺激装置 |
| EP4473002A4 (en) * | 2022-01-31 | 2026-04-08 | Hughes Howard Med Inst | Modified ion channels sensitive to a ligand and methods of use |
| CN119137144A (zh) * | 2022-02-18 | 2024-12-13 | 特拉梅斯生物股份有限公司 | 用于神经系统疾病的组合物和方法 |
| KR20240161957A (ko) * | 2022-02-18 | 2024-11-13 | 트라메스 바이오 인코포레이티드 | 리간드 개폐 이온 통로 및 사용 방법 |
| WO2025015092A1 (en) * | 2023-07-10 | 2025-01-16 | Kriya Therapeutics, Inc. | Novel cam-kinase promoter and uses thereof for treating nervous system disorders |
| CN121866054A (zh) * | 2023-08-16 | 2026-04-14 | 拜尔吉生物股份有限公司 | 用于治疗癫痫发作的方法 |
| GB202401492D0 (en) | 2024-02-05 | 2024-03-20 | Ucl Business Ltd | Chloride channels and uses thereof |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69434067T2 (de) * | 1993-03-08 | 2006-03-02 | Merck & Co., Inc. | Menschliche neuronale nikotin-acetylcholin-rezeptor-verbindungen und methoden ihres einsatzes |
| WO1995013365A1 (en) | 1993-11-09 | 1995-05-18 | Targeted Genetics Corporation | Generation of high titers of recombinant aav vectors |
| EP0893950A4 (en) | 1996-03-26 | 2002-02-27 | Univ California | SELECTIVE TARGET CELL ACTIVATION BY EXPRESSION OF A RECEPTOR SPECIFICALLY ACTIVATED BY SYNTHETIC LIGANDS |
| FR2756297B1 (fr) | 1996-11-22 | 1999-01-08 | Centre Nat Rech Scient | Procede de production de virus recombinants |
| AU8672198A (en) | 1997-07-31 | 1999-02-22 | Chiron Corporation | Method enabling readministration of aav vector via immunosuppression of host |
| US6566118B1 (en) | 1997-09-05 | 2003-05-20 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| DK1009808T3 (da) | 1997-09-05 | 2013-01-21 | Genzyme Corp | Fremgangsmåder til generering af hjælper-frie præparater af rekombinante aav-vektorer med høj titer |
| US6989264B2 (en) | 1997-09-05 | 2006-01-24 | Targeted Genetics Corporation | Methods for generating high titer helper-free preparations of released recombinant AAV vectors |
| AU780231B2 (en) | 1998-11-10 | 2005-03-10 | University Of North Carolina At Chapel Hill, The | Virus vectors and methods of making and administering the same |
| AU4980200A (en) | 1999-05-27 | 2000-12-18 | Pharmacia & Upjohn Company | Methods and compositions for measuring ion channel conductance |
| US6498244B1 (en) | 1999-05-28 | 2002-12-24 | Cell Genesys, Inc. | Adeno-associated virus capsid immunologic determinants |
| JP2003523320A (ja) | 1999-09-29 | 2003-08-05 | ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア | ウイルスベクターの迅速なｐｅｇ改変方法、高められた遺伝子形質導入のための組成物、高められた物理的安定性を伴う組成物、およびそのための用途 |
| EP1280902A2 (en) | 2000-04-29 | 2003-02-05 | Millennium Pharmaceuticals, Inc. | 23949 and 32391, human ion channels and uses thereof |
| EP1532452A4 (en) | 2002-05-31 | 2006-11-29 | Sloan Kettering Inst Cancer | HETEROLOGY STIMULUS-CONTROLLED ION CHANNELS AND METHOD FOR USE THEREOF |
| SI1633772T1 (sl) | 2003-06-19 | 2016-06-30 | Genzyme Corporation | AAV virioni z zmanjšano imunoreaktivnostjo in uporaba za ta namen |
| US9441244B2 (en) | 2003-06-30 | 2016-09-13 | The Regents Of The University Of California | Mutant adeno-associated virus virions and methods of use thereof |
| US20060166363A1 (en) | 2004-01-27 | 2006-07-27 | Sergei Zolotukhin | Modified baculovirus expression system for production of pseudotyped rAAV vector |
| WO2008143875A1 (en) | 2007-05-14 | 2008-11-27 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Targeted delivery of glycine receptors to excitable cells |
| EP2344636B1 (en) * | 2008-10-09 | 2017-12-06 | Howard Hughes Medical Institute | Novel chimeric ligand-gated ion channels and methods of use thereof |
| WO2014093251A1 (en) * | 2012-12-10 | 2014-06-19 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Engineered receptors and their use |
| GB201404470D0 (en) | 2014-03-13 | 2014-04-30 | Ucl Business Plc | Therapeutic methods and materials |
| US10682424B2 (en) | 2015-03-31 | 2020-06-16 | New York University | Compositions and method for reducing seizures |
| AU2016324317A1 (en) | 2015-09-17 | 2018-03-08 | Coda Biotherapeutics, Inc. | Compositions and methods for treating neurological disorders |
| IL304040B2 (en) | 2016-07-07 | 2024-09-01 | Hughes Howard Med Inst | Modified ligand-gated ion channels and methods of use |
| US11713470B2 (en) | 2017-03-20 | 2023-08-01 | University of Pittsburgh—of the Commonwealth System of Higher Education | Targeted gene therapies for pain and other neuro-related disorders |
-
2018
- 2018-11-27 US US16/201,142 patent/US10538571B2/en active Active
- 2018-11-27 EP EP18881318.2A patent/EP3716990A4/en active Pending
- 2018-11-27 KR KR1020207016109A patent/KR20200112811A/ko not_active Ceased
- 2018-11-27 AU AU2018373279A patent/AU2018373279B2/en active Active
- 2018-11-27 JP JP2020546302A patent/JP2021503960A/ja active Pending
- 2018-11-27 CA CA3082907A patent/CA3082907A1/en active Pending
- 2018-11-27 IL IL274702A patent/IL274702B2/en unknown
- 2018-11-27 SG SG11202004488TA patent/SG11202004488TA/en unknown
- 2018-11-27 WO PCT/US2018/062575 patent/WO2019104307A1/en not_active Ceased
- 2018-11-27 KR KR1020267002196A patent/KR20260030128A/ko active Pending
- 2018-11-27 MX MX2020005470A patent/MX2020005470A/es unknown
- 2018-11-27 CN CN201880085562.7A patent/CN111741760A/zh active Pending
-
2020
- 2020-07-09 US US16/925,174 patent/US20210061873A1/en active Pending
- 2020-07-13 MX MX2024014448A patent/MX2024014448A/es unknown
-
2024
- 2024-06-28 JP JP2024105712A patent/JP2024160218A/ja active Pending
- 2024-10-23 AU AU2024227560A patent/AU2024227560A1/en active Pending
- 2024-11-21 ZA ZA2024/08862A patent/ZA202408862B/en unknown
-
2025
- 2025-11-19 IL IL324810A patent/IL324810A/en unknown