JP2021503952A5 - - Google Patents

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Publication number
JP2021503952A5
JP2021503952A5 JP2020545859A JP2020545859A JP2021503952A5 JP 2021503952 A5 JP2021503952 A5 JP 2021503952A5 JP 2020545859 A JP2020545859 A JP 2020545859A JP 2020545859 A JP2020545859 A JP 2020545859A JP 2021503952 A5 JP2021503952 A5 JP 2021503952A5
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JP
Japan
Prior art keywords
cells
1rap
cell
car
region
Prior art date
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Application number
JP2020545859A
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English (en)
Japanese (ja)
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JP2021503952A (ja
JP7307083B2 (ja
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Priority claimed from EP17306630.9A external-priority patent/EP3489259A1/en
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Publication of JP2021503952A publication Critical patent/JP2021503952A/ja
Publication of JP2021503952A5 publication Critical patent/JP2021503952A5/ja
Priority to JP2023106930A priority Critical patent/JP7628155B2/ja
Application granted granted Critical
Publication of JP7307083B2 publication Critical patent/JP7307083B2/ja
Active legal-status Critical Current
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JP2020545859A 2017-11-23 2018-11-14 Il-1rapを標的とするcar-t細胞及びその使用 Active JP7307083B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023106930A JP7628155B2 (ja) 2017-11-23 2023-06-29 Il-1rapを標的とするcar-t細胞及びその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17306630.9 2017-11-23
EP17306630.9A EP3489259A1 (en) 2017-11-23 2017-11-23 Anti-il-1rap-car-t cells and their use
PCT/EP2018/081273 WO2019101604A1 (en) 2017-11-23 2018-11-14 Car-t cells targeting il-1rap and their use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023106930A Division JP7628155B2 (ja) 2017-11-23 2023-06-29 Il-1rapを標的とするcar-t細胞及びその使用

Publications (3)

Publication Number Publication Date
JP2021503952A JP2021503952A (ja) 2021-02-15
JP2021503952A5 true JP2021503952A5 (https=) 2021-03-25
JP7307083B2 JP7307083B2 (ja) 2023-07-11

Family

ID=60654888

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2020545859A Active JP7307083B2 (ja) 2017-11-23 2018-11-14 Il-1rapを標的とするcar-t細胞及びその使用
JP2023106930A Active JP7628155B2 (ja) 2017-11-23 2023-06-29 Il-1rapを標的とするcar-t細胞及びその使用

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023106930A Active JP7628155B2 (ja) 2017-11-23 2023-06-29 Il-1rapを標的とするcar-t細胞及びその使用

Country Status (8)

Country Link
US (2) US11839630B2 (https=)
EP (2) EP3489259A1 (https=)
JP (2) JP7307083B2 (https=)
KR (1) KR102730900B1 (https=)
CN (1) CN111712517B (https=)
AU (1) AU2018371071B2 (https=)
CA (1) CA3080451A1 (https=)
WO (1) WO2019101604A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3066918A1 (en) 2017-06-12 2018-12-20 Bluefin Biomedicine, Inc. Anti-il1rap antibodies and antibody drug conjugates
EP3489259A1 (en) * 2017-11-23 2019-05-29 Etablissement Français du Sang Anti-il-1rap-car-t cells and their use
EP3744400A1 (en) * 2019-05-28 2020-12-02 Etablissement Français du Sang Car-t cells targeting il-1rap and their use in acute myeloid leukemia (aml)
WO2021207709A1 (en) * 2020-04-10 2021-10-14 Seattle Children's Hospital (dba Seattle Children's Research Institute) Binders and chimeric antigen receptors specific for interleukin-1 receptor accessory protein
WO2024150177A1 (en) 2023-01-11 2024-07-18 Advesya Treatment methods for solid tumors
WO2025104669A1 (en) 2023-11-15 2025-05-22 Advesya Anti-il-1rap car-t cells for the treatment of acute myeloid leukemia

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB201403875D0 (en) * 2014-03-05 2014-04-16 Cantargia Ab Novel antibodies and uses thereof
WO2015158671A1 (en) 2014-04-14 2015-10-22 Cellectis Bcma (cd269) specific chimeric antigen receptors for cancer immunotherapy
GB201413913D0 (en) 2014-08-06 2014-09-17 Cantargia Ab Novel antibodies and uses thereof
AU2016350705A1 (en) * 2015-11-02 2018-05-17 Janssen Pharmaceutica Nv Anti-IL1RAP antibodies, bispecific antigen binding molecules that bind IL1RAP and CD3, and uses thereof
CN106831998B (zh) * 2016-06-22 2020-09-15 徐州医科大学 一种人il1rap特异性car及其应用
EP3489259A1 (en) * 2017-11-23 2019-05-29 Etablissement Français du Sang Anti-il-1rap-car-t cells and their use
EP3744400A1 (en) * 2019-05-28 2020-12-02 Etablissement Français du Sang Car-t cells targeting il-1rap and their use in acute myeloid leukemia (aml)

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