JP2021502964A - ブラウティア(Blautia)株を使用して疾患を処置するための組成物及び方法 - Google Patents
ブラウティア(Blautia)株を使用して疾患を処置するための組成物及び方法 Download PDFInfo
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- JP2021502964A JP2021502964A JP2020526214A JP2020526214A JP2021502964A JP 2021502964 A JP2021502964 A JP 2021502964A JP 2020526214 A JP2020526214 A JP 2020526214A JP 2020526214 A JP2020526214 A JP 2020526214A JP 2021502964 A JP2021502964 A JP 2021502964A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/742—Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762585782P | 2017-11-14 | 2017-11-14 | |
| US62/585,782 | 2017-11-14 | ||
| PCT/US2018/060998 WO2019099482A1 (en) | 2017-11-14 | 2018-11-14 | Compositions and methods for treating disease using a blautia strain |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021502964A true JP2021502964A (ja) | 2021-02-04 |
| JP2021502964A5 JP2021502964A5 (enExample) | 2021-12-23 |
Family
ID=64746632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020526214A Pending JP2021502964A (ja) | 2017-11-14 | 2018-11-14 | ブラウティア(Blautia)株を使用して疾患を処置するための組成物及び方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10493113B2 (enExample) |
| EP (1) | EP3710023A1 (enExample) |
| JP (1) | JP2021502964A (enExample) |
| CN (1) | CN111601610A (enExample) |
| AR (1) | AR113881A1 (enExample) |
| TW (1) | TW201936203A (enExample) |
| WO (1) | WO2019099482A1 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022525394A (ja) * | 2019-05-10 | 2022-05-13 | フォーディー ファーマ リサーチ リミテッド | 細菌株を含む組成物 |
| WO2023176950A1 (ja) | 2022-03-18 | 2023-09-21 | 株式会社明治 | 腸管内での細菌の増殖制御用組成物及びその利用 |
| WO2025070283A1 (ja) * | 2023-09-25 | 2025-04-03 | オルト株式会社 | ブラウティア属細菌を用いた免疫賦活剤 |
| WO2025070280A1 (ja) * | 2023-09-25 | 2025-04-03 | オルト株式会社 | ブラウティア属細菌 |
| JP2025054170A (ja) * | 2023-09-25 | 2025-04-07 | オルト株式会社 | ブラウティア属細菌を用いた免疫賦活剤 |
| JP2025054169A (ja) * | 2023-09-25 | 2025-04-07 | オルト株式会社 | ブラウティア属細菌 |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL265109B2 (en) | 2016-09-13 | 2024-05-01 | Allergan Inc | Stabilized non-protein clostridial toxin compositions |
| CN116196425A (zh) | 2016-09-27 | 2023-06-02 | 得克萨斯系统大学评议会 | 通过调节微生物组来增强免疫检查点阻断疗法的方法 |
| US11241461B2 (en) * | 2017-08-29 | 2022-02-08 | Evelo Biosciences, Inc. | Treating cancer using a blautia strain |
| US10493113B2 (en) | 2017-11-14 | 2019-12-03 | Evelo Biosciences, Inc. | Compositions and methods for treating disease using a Blautia strain |
| EP3746121A1 (en) * | 2018-01-31 | 2020-12-09 | Evelo Biosciences, Inc. | Compositions and methods for treating immune disorders using lachnospiraceae bacteria |
| JP7340591B2 (ja) * | 2018-07-11 | 2023-09-07 | アクティム・セラピューティクス・インコーポレイテッド | 遺伝子操作された免疫刺激性細菌菌株およびその使用 |
| CA3120709A1 (en) | 2018-11-21 | 2020-05-28 | Board Of Regents, The University Of Texas System | Methods and compositions for treating cancer |
| US20220080001A1 (en) * | 2019-01-16 | 2022-03-17 | Board Of Regents, The University Of Texas System | Methods and compositions for treating immune checkpoint inhibitor associated colitis |
| WO2020252144A1 (en) * | 2019-06-11 | 2020-12-17 | Evelo Biosciences, Inc. | Secreted microbial extracellular vesicles |
| CN112442455B (zh) * | 2019-09-03 | 2022-04-01 | 北京量化健康科技有限公司 | 具有防治高血脂症功能的布劳特氏菌以及产品组合物及其制备方法和应用 |
| CN111304120B (zh) * | 2020-02-24 | 2021-07-23 | 浙江大学 | Blautia sp B2132菌在预防和/或治疗炎症性肠病中的应用 |
| AU2021280299B2 (en) | 2020-05-28 | 2025-08-21 | Trench Therapeutics, Inc. | Airway medicaments |
| AR122610A1 (es) * | 2020-06-11 | 2022-09-21 | Evelo Biosciences Inc | Composiciones y métodos para el tratamiento de enfermedades y trastornos usando vesículas extracelulares microbianas de oscillospiraceae |
| WO2021252861A1 (en) * | 2020-06-11 | 2021-12-16 | Evelo Biosciences, Inc. | Compositions and methods for treating diseases and disorders using megasphaera sp |
| CN115768448A (zh) * | 2020-06-11 | 2023-03-07 | 伊夫罗生物科学公司 | 使用马西里福涅拉氏菌治疗疾病和障碍的组合物和方法 |
| CN113842497B (zh) * | 2021-09-28 | 2022-05-17 | 太原理工大学 | 一种具有光控抗菌和自愈合功能的CuS@Cur杂化水凝胶敷料的制备方法 |
| CN114225024B (zh) * | 2021-12-29 | 2022-08-19 | 山东健袖生态科技有限公司 | 一种用于治疗疾病的益生菌药物 |
| WO2023192360A1 (en) * | 2022-03-31 | 2023-10-05 | Incelldx, Inc. | Methods of treating a subject for post-treatment lyme disease (ptld) and compositions for use in the same |
| US20250235433A1 (en) * | 2022-04-19 | 2025-07-24 | Cedars-Sinai Medical Center | Methods of treating and diagnosing fatty liver disease |
| CN114806979A (zh) * | 2022-06-29 | 2022-07-29 | 杭州师范大学附属医院(杭州市第二人民医院) | 一种治疗非酒精性脂肪性肝病的益生菌复合物及其应用 |
| CN116254198B (zh) * | 2023-01-05 | 2024-03-26 | 中国科学院微生物研究所 | 一种布劳特氏菌及其应用 |
| CN116549465B (zh) * | 2023-04-26 | 2025-02-11 | 复旦大学附属中山医院 | Aldh2小分子激动剂在制备治疗心血管疾病及其代谢性疾病的药物中的应用 |
| CN117617181B (zh) * | 2023-12-27 | 2025-10-28 | 中国医学科学院皮肤病医院(中国医学科学院皮肤病研究所) | 一种系统性红斑狼疮小鼠模型的构建方法和应用 |
| CN119709558B (zh) * | 2025-02-26 | 2025-05-30 | 昆明医科大学第一附属医院(云南省皮肤病医院) | 布劳特氏菌emf75-02b1b及其用途 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016203218A1 (en) * | 2015-06-15 | 2016-12-22 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| WO2017035188A1 (en) * | 2015-08-24 | 2017-03-02 | Nubyiota Llc | Systems and methods for treating a dysbiosis using fecal-derived bacterial populations |
| CN107083339A (zh) * | 2017-03-01 | 2017-08-22 | 华中农业大学 | 防治仔猪腹泻的复合益生菌制剂及其制备方法和应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6368586B1 (en) | 1996-01-26 | 2002-04-09 | Brown University Research Foundation | Methods and compositions for enhancing the bioadhesive properties of polymers |
| AU2014239883B2 (en) | 2013-03-14 | 2019-01-17 | Therabiome, Llc | Targeted gastrointestinal tract delivery of probiotic organisms and/or therapeutic agents |
| WO2014201037A2 (en) * | 2013-06-10 | 2014-12-18 | New York University | Methods for manipulating immune responses by altering microbiota |
| AU2015353465B2 (en) * | 2014-11-25 | 2021-07-29 | Memorial Sloan-Kettering Cancer Center | Intestinal microbiota and GVHD |
| MA41020A (fr) * | 2014-11-25 | 2017-10-03 | Evelo Biosciences Inc | Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome |
| US9492473B2 (en) * | 2015-01-26 | 2016-11-15 | Kaleido Biosciences, Inc. | Glycan therapeutics and related methods thereof |
| EP3964234A1 (en) * | 2015-04-23 | 2022-03-09 | Kaleido Biosciences, Inc. | Glycan therapeutics and methods of treatment |
| US10493113B2 (en) * | 2017-11-14 | 2019-12-03 | Evelo Biosciences, Inc. | Compositions and methods for treating disease using a Blautia strain |
-
2018
- 2018-11-14 US US16/190,735 patent/US10493113B2/en active Active
- 2018-11-14 TW TW107140449A patent/TW201936203A/zh unknown
- 2018-11-14 AR ARP180103328A patent/AR113881A1/es unknown
- 2018-11-14 CN CN201880073533.9A patent/CN111601610A/zh active Pending
- 2018-11-14 JP JP2020526214A patent/JP2021502964A/ja active Pending
- 2018-11-14 EP EP18822542.9A patent/EP3710023A1/en not_active Withdrawn
- 2018-11-14 WO PCT/US2018/060998 patent/WO2019099482A1/en not_active Ceased
-
2019
- 2019-10-07 US US16/595,085 patent/US10702561B2/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2016203218A1 (en) * | 2015-06-15 | 2016-12-22 | 4D Pharma Research Limited | Compositions comprising bacterial strains |
| WO2017035188A1 (en) * | 2015-08-24 | 2017-03-02 | Nubyiota Llc | Systems and methods for treating a dysbiosis using fecal-derived bacterial populations |
| CN107083339A (zh) * | 2017-03-01 | 2017-08-22 | 华中农业大学 | 防治仔猪腹泻的复合益生菌制剂及其制备方法和应用 |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022525394A (ja) * | 2019-05-10 | 2022-05-13 | フォーディー ファーマ リサーチ リミテッド | 細菌株を含む組成物 |
| JP7075159B2 (ja) | 2019-05-10 | 2022-05-25 | フォーディー ファーマ リサーチ リミテッド | 細菌株を含む組成物 |
| WO2023176950A1 (ja) | 2022-03-18 | 2023-09-21 | 株式会社明治 | 腸管内での細菌の増殖制御用組成物及びその利用 |
| WO2025070283A1 (ja) * | 2023-09-25 | 2025-04-03 | オルト株式会社 | ブラウティア属細菌を用いた免疫賦活剤 |
| WO2025070280A1 (ja) * | 2023-09-25 | 2025-04-03 | オルト株式会社 | ブラウティア属細菌 |
| JP2025054170A (ja) * | 2023-09-25 | 2025-04-07 | オルト株式会社 | ブラウティア属細菌を用いた免疫賦活剤 |
| JP2025054169A (ja) * | 2023-09-25 | 2025-04-07 | オルト株式会社 | ブラウティア属細菌 |
| JP7706190B2 (ja) | 2023-09-25 | 2025-07-11 | オルト株式会社 | ブラウティア属細菌 |
| JP7706191B2 (ja) | 2023-09-25 | 2025-07-11 | オルト株式会社 | ブラウティア属細菌を用いた免疫賦活剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| TW201936203A (zh) | 2019-09-16 |
| AR113881A1 (es) | 2020-06-24 |
| US20190216862A1 (en) | 2019-07-18 |
| EP3710023A1 (en) | 2020-09-23 |
| CN111601610A8 (zh) | 2023-07-21 |
| WO2019099482A1 (en) | 2019-05-23 |
| US10493113B2 (en) | 2019-12-03 |
| US10702561B2 (en) | 2020-07-07 |
| CN111601610A (zh) | 2020-08-28 |
| US20200030389A1 (en) | 2020-01-30 |
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