JP2021502806A - 免疫細胞、特に非古典的単球の同定のためのエピジェネティックマーカーとしての単位複製配列領域 - Google Patents
免疫細胞、特に非古典的単球の同定のためのエピジェネティックマーカーとしての単位複製配列領域 Download PDFInfo
- Publication number
- JP2021502806A JP2021502806A JP2020523795A JP2020523795A JP2021502806A JP 2021502806 A JP2021502806 A JP 2021502806A JP 2020523795 A JP2020523795 A JP 2020523795A JP 2020523795 A JP2020523795 A JP 2020523795A JP 2021502806 A JP2021502806 A JP 2021502806A
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- JP
- Japan
- Prior art keywords
- seq
- monocytes
- cells
- methylation
- region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/154—Methylation markers
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102017125335.1A DE102017125335B4 (de) | 2017-10-27 | 2017-10-27 | Amplikon-Region als epigenetischer Marker zur Identifizierung von Immunzellen, insbesondere nicht-klassischer Monozyten |
| DE102017125335.1 | 2017-10-27 | ||
| PCT/EP2018/079406 WO2019081707A1 (en) | 2017-10-27 | 2018-10-26 | AMPLICON REGION AS AN EPIGENETIC MARKER FOR THE IDENTIFICATION OF NON-CLASSIC MONOCYTES |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021502806A true JP2021502806A (ja) | 2021-02-04 |
| JP2021502806A5 JP2021502806A5 (enExample) | 2021-11-25 |
Family
ID=64024040
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020523795A Pending JP2021502806A (ja) | 2017-10-27 | 2018-10-26 | 免疫細胞、特に非古典的単球の同定のためのエピジェネティックマーカーとしての単位複製配列領域 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US11680294B2 (enExample) |
| EP (1) | EP3669001B1 (enExample) |
| JP (1) | JP2021502806A (enExample) |
| CN (1) | CN111247253A (enExample) |
| AU (1) | AU2018356572A1 (enExample) |
| CA (1) | CA3079477A1 (enExample) |
| DE (1) | DE102017125335B4 (enExample) |
| WO (1) | WO2019081707A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022191293A1 (ja) * | 2021-03-12 | 2022-09-15 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 全単球及びcd16陽性単球の割合の測定方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016515397A (ja) * | 2013-04-19 | 2016-05-30 | エピオンティス ゲーエムベーハー | 生体サンプルにおける定量的細胞組成を特定する方法 |
| JP2016522830A (ja) * | 2013-05-22 | 2016-08-04 | イエダ リサーチ アンド ディベロップメント カンパニー リミテッド | 眼疾患および眼障害の治療のためのヒト単球亜集団 |
| WO2017050925A1 (en) * | 2015-09-25 | 2017-03-30 | Epiontis Gmbh | Park2 as epigenetic marker for the identification of immune cells, in particular monocytes |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2714933A4 (en) | 2011-05-25 | 2014-12-31 | Univ Brown | METHODIZED METHOD FOR IDENTIFYING A CELL OR MIXING CELLS FOR THE PROGNOSIS AND DIAGNOSIS OF ILLNESSES AND FOR CELL HEALING THERAPIES |
-
2017
- 2017-10-27 DE DE102017125335.1A patent/DE102017125335B4/de active Active
-
2018
- 2018-10-26 WO PCT/EP2018/079406 patent/WO2019081707A1/en not_active Ceased
- 2018-10-26 CN CN201880068476.5A patent/CN111247253A/zh not_active Withdrawn
- 2018-10-26 CA CA3079477A patent/CA3079477A1/en active Pending
- 2018-10-26 JP JP2020523795A patent/JP2021502806A/ja active Pending
- 2018-10-26 EP EP18793655.4A patent/EP3669001B1/en active Active
- 2018-10-26 US US16/758,992 patent/US11680294B2/en active Active
- 2018-10-26 AU AU2018356572A patent/AU2018356572A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2016515397A (ja) * | 2013-04-19 | 2016-05-30 | エピオンティス ゲーエムベーハー | 生体サンプルにおける定量的細胞組成を特定する方法 |
| JP2016522830A (ja) * | 2013-05-22 | 2016-08-04 | イエダ リサーチ アンド ディベロップメント カンパニー リミテッド | 眼疾患および眼障害の治療のためのヒト単球亜集団 |
| WO2017050925A1 (en) * | 2015-09-25 | 2017-03-30 | Epiontis Gmbh | Park2 as epigenetic marker for the identification of immune cells, in particular monocytes |
Non-Patent Citations (1)
| Title |
|---|
| ZAWADA A. M. ET AL.: "DNA methylation profiling reveals differences in the 3 human monocyte subsets and identifies uremia", EPIGENETICS, vol. 11, no. 4, JPN7022004257, 2016, pages 259 - 272, XP055965308, ISSN: 0004865914, DOI: 10.1080/15592294.2016.1158363 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022191293A1 (ja) * | 2021-03-12 | 2022-09-15 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 全単球及びcd16陽性単球の割合の測定方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA3079477A1 (en) | 2019-05-02 |
| US20200340053A1 (en) | 2020-10-29 |
| AU2018356572A1 (en) | 2020-04-23 |
| CN111247253A (zh) | 2020-06-05 |
| EP3669001B1 (en) | 2024-07-17 |
| US11680294B2 (en) | 2023-06-20 |
| DE102017125335B4 (de) | 2019-10-17 |
| DE102017125335A1 (de) | 2019-05-02 |
| WO2019081707A1 (en) | 2019-05-02 |
| EP3669001A1 (en) | 2020-06-24 |
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